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Items: 1 to 20 of 95

1.

Notch ligand Delta-like 4 regulates disease pathogenesis during respiratory viral infections by modulating Th2 cytokines.

Schaller MA, Neupane R, Rudd BD, Kunkel SL, Kallal LE, Lincoln P, Lowe JB, Man Y, Lukacs NW.

J Exp Med. 2007 Nov 26;204(12):2925-34. Epub 2007 Nov 6.

2.

Notch ligand delta-like 4 regulates development and pathogenesis of allergic airway responses by modulating IL-2 production and Th2 immunity.

Jang S, Schaller M, Berlin AA, Lukacs NW.

J Immunol. 2010 Nov 15;185(10):5835-44. doi: 10.4049/jimmunol.1000175. Epub 2010 Oct 13.

3.

MyD88-mediated instructive signals in dendritic cells regulate pulmonary immune responses during respiratory virus infection.

Rudd BD, Schaller MA, Smit JJ, Kunkel SL, Neupane R, Kelley L, Berlin AA, Lukacs NW.

J Immunol. 2007 May 1;178(9):5820-7.

4.

STAT5-induced lunatic fringe during Th2 development alters delta-like 4-mediated Th2 cytokine production in respiratory syncytial virus-exacerbated airway allergic disease.

Mukherjee S, Rasky AJ, Lundy PA, Kittan NA, Kunkel SL, Maillard IP, Kowalski PE, Kousis PC, Guidos CJ, Lukacs NW.

J Immunol. 2014 Feb 1;192(3):996-1003. doi: 10.4049/jimmunol.1301991. Epub 2013 Dec 23.

5.

T helper 1/T helper 2 cytokine imbalance in respiratory syncytial virus infection is associated with increased endogenous plasma cortisol.

Pinto RA, Arredondo SM, Bono MR, Gaggero AA, Díaz PV.

Pediatrics. 2006 May;117(5):e878-86. Epub 2006 Apr 17.

PMID:
16618789
6.

STAT4 deficiency fails to induce lung Th2 or Th17 immunity following primary or secondary respiratory syncytial virus (RSV) challenge but enhances the lung RSV-specific CD8+ T cell immune response to secondary challenge.

Dulek DE, Newcomb DC, Toki S, Goliniewska K, Cephus J, Reiss S, Bates JT, Crowe JE Jr, Boyd KL, Moore ML, Zhou W, Peebles RS Jr.

J Virol. 2014 Sep 1;88(17):9655-72. doi: 10.1128/JVI.03299-13. Epub 2014 Jun 11.

7.

Prophylaxis with a respiratory syncytial virus (RSV) anti-G protein monoclonal antibody shifts the adaptive immune response to RSV rA2-line19F infection from Th2 to Th1 in BALB/c mice.

Boyoglu-Barnum S, Chirkova T, Todd SO, Barnum TR, Gaston KA, Jorquera P, Haynes LM, Tripp RA, Moore ML, Anderson LJ.

J Virol. 2014 Sep;88(18):10569-83. doi: 10.1128/JVI.01503-14. Epub 2014 Jul 2.

8.

Virus-Like Particle Vaccine Containing the F Protein of Respiratory Syncytial Virus Confers Protection without Pulmonary Disease by Modulating Specific Subsets of Dendritic Cells and Effector T Cells.

Kim KH, Lee YT, Hwang HS, Kwon YM, Kim MC, Ko EJ, Lee JS, Lee Y, Kang SM.

J Virol. 2015 Nov;89(22):11692-705. doi: 10.1128/JVI.02018-15. Epub 2015 Sep 9.

9.

IL-12p40 and IL-18 modulate inflammatory and immune responses to respiratory syncytial virus infection.

Wang SZ, Bao YX, Rosenberger CL, Tesfaigzi Y, Stark JM, Harrod KS.

J Immunol. 2004 Sep 15;173(6):4040-9.

10.
11.

IL-17-induced pulmonary pathogenesis during respiratory viral infection and exacerbation of allergic disease.

Mukherjee S, Lindell DM, Berlin AA, Morris SB, Shanley TP, Hershenson MB, Lukacs NW.

Am J Pathol. 2011 Jul;179(1):248-58. doi: 10.1016/j.ajpath.2011.03.003. Epub 2011 May 3.

12.

RSV-Induced H3K4 Demethylase KDM5B Leads to Regulation of Dendritic Cell-Derived Innate Cytokines and Exacerbates Pathogenesis In Vivo.

Ptaschinski C, Mukherjee S, Moore ML, Albert M, Helin K, Kunkel SL, Lukacs NW.

PLoS Pathog. 2015 Jun 17;11(6):e1004978. doi: 10.1371/journal.ppat.1004978. eCollection 2015 Jun.

13.

Limited type I interferons and plasmacytoid dendritic cells during neonatal respiratory syncytial virus infection permit immunopathogenesis upon reinfection.

Cormier SA, Shrestha B, Saravia J, Lee GI, Shen L, DeVincenzo JP, Kim YI, You D.

J Virol. 2014 Aug;88(16):9350-60. doi: 10.1128/JVI.00818-14. Epub 2014 Jun 11.

14.

NK cell deficiency predisposes to viral-induced Th2-type allergic inflammation via epithelial-derived IL-25.

Kaiko GE, Phipps S, Angkasekwinai P, Dong C, Foster PS.

J Immunol. 2010 Oct 15;185(8):4681-90. doi: 10.4049/jimmunol.1001758. Epub 2010 Sep 20.

16.

Regulation of mite allergen-pulsed murine dendritic cells by respiratory syncytial virus.

Kondo Y, Matsuse H, Machida I, Kawano T, Saeki S, Tomari S, Obase Y, Fukushima C, Kohno S.

Am J Respir Crit Care Med. 2004 Feb 15;169(4):494-8. Epub 2003 Dec 4.

PMID:
14656751
17.

Efficient lung recruitment of respiratory syncytial virus-specific Th1 cells induced by recombinant bacillus Calmette-Guérin promotes virus clearance and protects from infection.

Cautivo KM, Bueno SM, Cortes CM, Wozniak A, Riedel CA, Kalergis AM.

J Immunol. 2010 Dec 15;185(12):7633-45. doi: 10.4049/jimmunol.0903452. Epub 2010 Nov 17.

18.

TLR9 regulates the mycobacteria-elicited pulmonary granulomatous immune response in mice through DC-derived Notch ligand delta-like 4.

Ito T, Schaller M, Hogaboam CM, Standiford TJ, Sandor M, Lukacs NW, Chensue SW, Kunkel SL.

J Clin Invest. 2009 Jan;119(1):33-46. doi: 10.1172/JCI35647. Epub 2008 Dec 15.

19.

Immunomodulation with IL-4R alpha antisense oligonucleotide prevents respiratory syncytial virus-mediated pulmonary disease.

Ripple MJ, You D, Honnegowda S, Giaimo JD, Sewell AB, Becnel DM, Cormier SA.

J Immunol. 2010 Oct 15;185(8):4804-11. doi: 10.4049/jimmunol.1000484. Epub 2010 Sep 22.

20.

Inhibition of STAT6 during vaccination with formalin-inactivated RSV prevents induction of Th2-cell-biased airway disease.

Srinivasa BT, Fixman ED, Ward BJ.

Eur J Immunol. 2014 Aug;44(8):2349-59. doi: 10.1002/eji.201344206. Epub 2014 Jun 5.

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