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Items: 1 to 20 of 93


Pollen proteolytic enzymes degrade tight junctions.

Runswick S, Mitchell T, Davies P, Robinson C, Garrod DR.

Respirology. 2007 Nov;12(6):834-42.


Mass spectrometric analysis of electrophoretically separated allergens and proteases in grass pollen diffusates.

Raftery MJ, Saldanha RG, Geczy CL, Kumar RK.

Respir Res. 2003;4:10. Epub 2003 Sep 20.


Pollen proteases compromise the airway epithelial barrier through degradation of transmembrane adhesion proteins and lung bioactive peptides.

Vinhas R, Cortes L, Cardoso I, Mendes VM, Manadas B, Todo-Bom A, Pires E, Veríssimo P.

Allergy. 2011 Aug;66(8):1088-98. doi: 10.1111/j.1398-9995.2011.02598.x. Epub 2011 Apr 11.


The transmembrane protein occludin of epithelial tight junctions is a functional target for serine peptidases from faecal pellets of Dermatophagoides pteronyssinus.

Wan H, Winton HL, Soeller C, Taylor GW, Gruenert DC, Thompson PJ, Cannell MB, Stewart GA, Garrod DR, Robinson C.

Clin Exp Allergy. 2001 Feb;31(2):279-94.


Quantitative structural and biochemical analyses of tight junction dynamics following exposure of epithelial cells to house dust mite allergen Der p 1.

Wan H, Winton HL, Soeller C, Gruenert DC, Thompson PJ, Cannell MB, Stewart GA, Garrod DR, Robinson C.

Clin Exp Allergy. 2000 May;30(5):685-98.


Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions.

Wan H, Winton HL, Soeller C, Tovey ER, Gruenert DC, Thompson PJ, Stewart GA, Taylor GW, Garrod DR, Cannell MB, Robinson C.

J Clin Invest. 1999 Jul;104(1):123-33.


Injury to murine airway epithelial cells by pollen enzymes.

Hassim Z, Maronese SE, Kumar RK.

Thorax. 1998 May;53(5):368-71.


Zonula occludens-1 function in the assembly of tight junctions in Madin-Darby canine kidney epithelial cells.

McNeil E, Capaldo CT, Macara IG.

Mol Biol Cell. 2006 Apr;17(4):1922-32. Epub 2006 Jan 25.


Occludin is a functional component of the tight junction.

McCarthy KM, Skare IB, Stankewich MC, Furuse M, Tsukita S, Rogers RA, Lynch RD, Schneeberger EE.

J Cell Sci. 1996 Sep;109 ( Pt 9):2287-98.


Substrate preference profiles of proteases released by allergenic pollens.

Widmer F, Hayes PJ, Whittaker RG, Kumar RK.

Clin Exp Allergy. 2000 Apr;30(4):571-6.


Protein kinase Cζ phosphorylates occludin and promotes assembly of epithelial tight junctions.

Jain S, Suzuki T, Seth A, Samak G, Rao R.

Biochem J. 2011 Jul 15;437(2):289-99. doi: 10.1042/BJ20110587.


Meprin A impairs epithelial barrier function, enhances monocyte migration, and cleaves the tight junction protein occludin.

Bao J, Yura RE, Matters GL, Bradley SG, Shi P, Tian F, Bond JS.

Am J Physiol Renal Physiol. 2013 Sep 1;305(5):F714-26. doi: 10.1152/ajprenal.00179.2012. Epub 2013 Jun 26.


Characterization of Porphyromonas gingivalis-induced degradation of epithelial cell junctional complexes.

Katz J, Sambandam V, Wu JH, Michalek SM, Balkovetz DF.

Infect Immun. 2000 Mar;68(3):1441-9.


Matrix metalloproteinase-2 and -9 secreted by leukemic cells increase the permeability of blood-brain barrier by disrupting tight junction proteins.

Feng S, Cen J, Huang Y, Shen H, Yao L, Wang Y, Chen Z.

PLoS One. 2011;6(8):e20599. doi: 10.1371/journal.pone.0020599. Epub 2011 Aug 17. Erratum in: PLoS One. 2011;6(8). doi: 10.1371/annotation/716c0fb2-dbdd-4da5-ad8a-d2b1cdac4ec6.


Specific modulation of airway epithelial tight junctions by apical application of an occludin peptide.

Everett RS, Vanhook MK, Barozzi N, Toth I, Johnson LG.

Mol Pharmacol. 2006 Feb;69(2):492-500. Epub 2005 Nov 15.


House dust mite allergen Der p 1 effects on sinonasal epithelial tight junctions.

Henriquez OA, Den Beste K, Hoddeson EK, Parkos CA, Nusrat A, Wise SK.

Int Forum Allergy Rhinol. 2013 Aug;3(8):630-5. doi: 10.1002/alr.21168. Epub 2013 Apr 16.


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