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Items: 1 to 20 of 82

1.

Cutting edge: identification of a pre-ligand assembly domain (PLAD) and ligand binding site in the IL-17 receptor.

Kramer JM, Hanel W, Shen F, Isik N, Malone JP, Maitra A, Sigurdson W, Swart D, Tocker J, Jin T, Gaffen SL.

J Immunol. 2007 Nov 15;179(10):6379-83.

2.

Structure of the unique SEFIR domain from human interleukin 17 receptor A reveals a composite ligand-binding site containing a conserved α-helix for Act1 binding and IL-17 signaling.

Zhang B, Liu C, Qian W, Han Y, Li X, Deng J.

Acta Crystallogr D Biol Crystallogr. 2014 May;70(Pt 5):1476-83. doi: 10.1107/S1399004714005227. Epub 2014 Apr 30.

3.

Structural basis of receptor sharing by interleukin 17 cytokines.

Ely LK, Fischer S, Garcia KC.

Nat Immunol. 2009 Dec;10(12):1245-51. doi: 10.1038/ni.1813. Epub 2009 Oct 18.

4.

A CC' loop decoy peptide blocks the interaction between Act1 and IL-17RA to attenuate IL-17- and IL-25-induced inflammation.

Liu C, Swaidani S, Qian W, Kang Z, Sun P, Han Y, Wang C, Gulen MF, Yin W, Zhang C, Fox PL, Aronica M, Hamilton TA, Misra S, Deng J, Li X.

Sci Signal. 2011 Nov 1;4(197):ra72. doi: 10.1126/scisignal.2001843.

5.

Evidence for ligand-independent multimerization of the IL-17 receptor.

Kramer JM, Yi L, Shen F, Maitra A, Jiao X, Jin T, Gaffen SL.

J Immunol. 2006 Jan 15;176(2):711-5. Erratum in: J Immunol. 2007 Dec 15;179(12):8569.

6.

An Overview of Interleukin-17A and Interleukin-17 Receptor A Structure, Interaction and Signaling.

Krstic J, Obradovic H, Kukolj T, Mojsilovic S, Okic-Dordevic I, Bugarski D, Santibanez JF.

Protein Pept Lett. 2015;22(7):570-8. Review.

PMID:
25990083
7.

Lentivirus mediated IL-17R blockade improves diastolic cardiac function in spontaneously hypertensive rats.

Liu W, Wang X, Feng W, Li S, Tian W, Xu T, Song Y, Zhang Z.

Exp Mol Pathol. 2011 Aug;91(1):362-7. doi: 10.1016/j.yexmp.2011.04.003. Epub 2011 Apr 21.

PMID:
21530504
8.

Importance of the membrane-proximal extracellular domains for activation of the signal transducer glycoprotein 130.

Kurth I, Horsten U, Pflanz S, Timmermann A, Küster A, Dahmen H, Tacken I, Heinrich PC, Müller-Newen G.

J Immunol. 2000 Jan 1;164(1):273-82.

9.

Identification of the domain in the human interleukin-11 receptor that mediates ligand binding.

Schleinkofer K, Dingley A, Tacken I, Federwisch M, Müller-Newen G, Heinrich PC, Vusio P, Jacques Y, Grötzinger J.

J Mol Biol. 2001 Feb 16;306(2):263-74.

PMID:
11237599
10.

Structure and signalling in the IL-17 receptor family.

Gaffen SL.

Nat Rev Immunol. 2009 Aug;9(8):556-67. doi: 10.1038/nri2586. Epub 2009 Jul 3. Review. Erratum in: Nat Rev Immunol. 2009 Oct;9(10):747.

11.

Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expression.

Maitra A, Shen F, Hanel W, Mossman K, Tocker J, Swart D, Gaffen SL.

Proc Natl Acad Sci U S A. 2007 May 1;104(18):7506-11. Epub 2007 Apr 24.

12.
13.

Mapping of binding site III in the leptin receptor and modeling of a hexameric leptin.leptin receptor complex.

Peelman F, Iserentant H, De Smet AS, Vandekerckhove J, Zabeau L, Tavernier J.

J Biol Chem. 2006 Jun 2;281(22):15496-504. Epub 2006 Mar 15.

14.

Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F.

Kuestner RE, Taft DW, Haran A, Brandt CS, Brender T, Lum K, Harder B, Okada S, Ostrander CD, Kreindler JL, Aujla SJ, Reardon B, Moore M, Shea P, Schreckhise R, Bukowski TR, Presnell S, Guerra-Lewis P, Parrish-Novak J, Ellsworth JL, Jaspers S, Lewis KE, Appleby M, Kolls JK, Rixon M, West JW, Gao Z, Levin SD.

J Immunol. 2007 Oct 15;179(8):5462-73.

15.

Conformational dynamics and ligand binding in the multi-domain protein PDC109.

Kim HJ, Choi MY, Kim HJ, Llinás M.

PLoS One. 2010 Feb 18;5(2):e9180. doi: 10.1371/journal.pone.0009180.

16.

Critical role of IL-17RA in immunopathology of influenza infection.

Crowe CR, Chen K, Pociask DA, Alcorn JF, Krivich C, Enelow RI, Ross TM, Witztum JL, Kolls JK.

J Immunol. 2009 Oct 15;183(8):5301-10. doi: 10.4049/jimmunol.0900995. Epub 2009 Sep 25.

17.

Ligand selectivity and affinity of chemokine receptor CXCR1. Role of N-terminal domain.

Rajagopalan L, Rajarathnam K.

J Biol Chem. 2004 Jul 16;279(29):30000-8. Epub 2004 May 7.

18.

Structures of the EphA2 Receptor at the Membrane: Role of Lipid Interactions.

Chavent M, Seiradake E, Jones EY, Sansom MS.

Structure. 2016 Feb 2;24(2):337-47. doi: 10.1016/j.str.2015.11.008. Epub 2015 Dec 24.

19.

IL-2 induces conformational changes in its preassembled receptor core, which then migrates in lipid raft and binds to the cytoskeleton meshwork.

Pillet AH, Lavergne V, Pasquier V, Gesbert F, Thèze J, Rose T.

J Mol Biol. 2010 Nov 12;403(5):671-92. doi: 10.1016/j.jmb.2010.08.056. Epub 2010 Sep 21.

PMID:
20816854
20.

Targeting pre-ligand assembly domain of TNFR1 ameliorates autoimmune diseases - an unrevealed role in downregulation of Th17 cells.

Wang YL, Chou FC, Chen SJ, Lin SH, Chang DM, Sytwu HK.

J Autoimmun. 2011 Nov;37(3):160-70. doi: 10.1016/j.jaut.2011.05.013. Epub 2011 Jul 1.

PMID:
21689905

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