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Items: 1 to 20 of 207

1.

Mechanisms of seizure-induced 'transcriptional channelopathy' of hyperpolarization-activated cyclic nucleotide gated (HCN) channels.

Richichi C, Brewster AL, Bender RA, Simeone TA, Zha Q, Yin HZ, Weiss JH, Baram TZ.

Neurobiol Dis. 2008 Feb;29(2):297-305. Epub 2007 Sep 22.

2.

Decreases in HCN mRNA expression in the hippocampus after kindling and status epilepticus in adult rats.

Powell KL, Ng C, O'Brien TJ, Xu SH, Williams DA, Foote SJ, Reid CA.

Epilepsia. 2008 Oct;49(10):1686-95. doi: 10.1111/j.1528-1167.2008.01593.x. Epub 2008 Apr 7.

3.

Activity-dependent heteromerization of the hyperpolarization-activated, cyclic-nucleotide gated (HCN) channels: role of N-linked glycosylation.

Zha Q, Brewster AL, Richichi C, Bender RA, Baram TZ.

J Neurochem. 2008 Apr;105(1):68-77. Epub 2007 Nov 5.

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Direct evidence for calcium conductance of hyperpolarization-activated cyclic nucleotide-gated channels and human native If at physiological calcium concentrations.

Michels G, Brandt MC, Zagidullin N, Khan IF, Larbig R, van Aaken S, Wippermann J, Hoppe UC.

Cardiovasc Res. 2008 Jun 1;78(3):466-75. doi: 10.1093/cvr/cvn032. Epub 2008 Feb 5. Erratum in: Cardiovasc Res. 2012 Sep 1;95(4):527.

PMID:
18252758
8.
9.

Neuron-restrictive silencer factor-mediated hyperpolarization-activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy.

McClelland S, Flynn C, Dubé C, Richichi C, Zha Q, Ghestem A, Esclapez M, Bernard C, Baram TZ.

Ann Neurol. 2011 Sep;70(3):454-64. doi: 10.1002/ana.22479.

10.

Trafficking and surface expression of hyperpolarization-activated cyclic nucleotide-gated channels in hippocampal neurons.

Noam Y, Zha Q, Phan L, Wu RL, Chetkovich DM, Wadman WJ, Baram TZ.

J Biol Chem. 2010 May 7;285(19):14724-36. doi: 10.1074/jbc.M109.070391. Epub 2010 Mar 9.

11.

HCN channelopathies: pathophysiology in genetic epilepsy and therapeutic implications.

Reid CA, Phillips AM, Petrou S.

Br J Pharmacol. 2012 Jan;165(1):49-56. doi: 10.1111/j.1476-5381.2011.01507.x. Review.

12.

In vitro characterization of HCN channel kinetics and frequency dependence in myocytes predicts biological pacemaker functionality.

Zhao X, Bucchi A, Oren RV, Kryukova Y, Dun W, Clancy CE, Robinson RB.

J Physiol. 2009 Apr 1;587(Pt 7):1513-25. doi: 10.1113/jphysiol.2008.163444. Epub 2009 Jan 26.

13.

Activity-dependent regulation of h channel distribution in hippocampal CA1 pyramidal neurons.

Shin M, Chetkovich DM.

J Biol Chem. 2007 Nov 9;282(45):33168-80. Epub 2007 Sep 11.

14.

Deletion of the hyperpolarization-activated cyclic nucleotide-gated channel auxiliary subunit TRIP8b impairs hippocampal Ih localization and function and promotes antidepressant behavior in mice.

Lewis AS, Vaidya SP, Blaiss CA, Liu Z, Stoub TR, Brager DH, Chen X, Bender RA, Estep CM, Popov AB, Kang CE, Van Veldhoven PP, Bayliss DA, Nicholson DA, Powell CM, Johnston D, Chetkovich DM.

J Neurosci. 2011 May 18;31(20):7424-40. doi: 10.1523/JNEUROSCI.0936-11.2011.

15.

Rapid loss of dendritic HCN channel expression in hippocampal pyramidal neurons following status epilepticus.

Jung S, Warner LN, Pitsch J, Becker AJ, Poolos NP.

J Neurosci. 2011 Oct 5;31(40):14291-5. doi: 10.1523/JNEUROSCI.1148-11.2011.

16.

Single channel properties of hyperpolarization-activated cation currents in acutely dissociated rat hippocampal neurones.

Simeone TA, Rho JM, Baram TZ.

J Physiol. 2005 Oct 15;568(Pt 2):371-80. Epub 2005 Aug 25.

18.

Excitotoxic-mediated transcriptional decreases in HCN2 channel function increase network excitability in CA1.

Adams BE, Reid CA, Myers D, Ng C, Powell K, Phillips AM, Zheng T, O'Brien TJ, Williams DA.

Exp Neurol. 2009 Sep;219(1):249-57. doi: 10.1016/j.expneurol.2009.05.030. Epub 2009 Jun 3.

PMID:
19500574
19.

Differential expression of HCN subunits alters voltage-dependent gating of h-channels in CA1 pyramidal neurons from dorsal and ventral hippocampus.

Dougherty KA, Nicholson DA, Diaz L, Buss EW, Neuman KM, Chetkovich DM, Johnston D.

J Neurophysiol. 2013 Apr;109(7):1940-53. doi: 10.1152/jn.00010.2013. Epub 2013 Jan 16.

20.

Associated changes in HCN2 and HCN4 transcripts and I(f) pacemaker current in myocytes.

Zhang Q, Huang A, Lin YC, Yu HG.

Biochim Biophys Acta. 2009 May;1788(5):1138-47. doi: 10.1016/j.bbamem.2009.02.011. Epub 2009 Feb 21.

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