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Items: 1 to 20 of 119

1.

BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module.

Park D, Tosello-Trampont AC, Elliott MR, Lu M, Haney LB, Ma Z, Klibanov AL, Mandell JW, Ravichandran KS.

Nature. 2007 Nov 15;450(7168):430-4.

PMID:
17960134
2.

Phagocytosis of apoptotic cells is regulated by a UNC-73/TRIO-MIG-2/RhoG signaling module and armadillo repeats of CED-12/ELMO.

deBakker CD, Haney LB, Kinchen JM, Grimsley C, Lu M, Klingele D, Hsu PK, Chou BK, Cheng LC, Blangy A, Sondek J, Hengartner MO, Wu YC, Ravichandran KS.

Curr Biol. 2004 Dec 29;14(24):2208-16.

3.

Identification of two signaling submodules within the CrkII/ELMO/Dock180 pathway regulating engulfment of apoptotic cells.

Tosello-Trampont AC, Kinchen JM, Brugnera E, Haney LB, Hengartner MO, Ravichandran KS.

Cell Death Differ. 2007 May;14(5):963-72. Epub 2007 Feb 16.

4.

Dock180-ELMO cooperation in Rac activation.

Lu M, Ravichandran KS.

Methods Enzymol. 2006;406:388-402.

PMID:
16472672
5.

C-terminal SH3 domain of CrkII regulates the assembly and function of the DOCK180/ELMO Rac-GEF.

Akakura S, Kar B, Singh S, Cho L, Tibrewal N, Sanokawa-Akakura R, Reichman C, Ravichandran KS, Birge RB.

J Cell Physiol. 2005 Jul;204(1):344-51.

PMID:
15700267
6.

Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex.

Brugnera E, Haney L, Grimsley C, Lu M, Walk SF, Tosello-Trampont AC, Macara IG, Madhani H, Fink GR, Ravichandran KS.

Nat Cell Biol. 2002 Aug;4(8):574-82.

PMID:
12134158
7.

Emerging roles of brain-specific angiogenesis inhibitor 1.

Park D, Ravichandran KS.

Adv Exp Med Biol. 2010;706:167-78. Review.

PMID:
21618836
8.

The adhesion-GPCR BAI1 regulates synaptogenesis by controlling the recruitment of the Par3/Tiam1 polarity complex to synaptic sites.

Duman JG, Tzeng CP, Tu YK, Munjal T, Schwechter B, Ho TS, Tolias KF.

J Neurosci. 2013 Apr 17;33(16):6964-78. doi: 10.1523/JNEUROSCI.3978-12.2013.

9.

Cross talk between engulfment receptors stabilin-2 and integrin αvβ5 orchestrates engulfment of phosphatidylserine-exposed erythrocytes.

Kim S, Park SY, Kim SY, Bae DJ, Pyo JH, Hong M, Kim IS.

Mol Cell Biol. 2012 Jul;32(14):2698-708. doi: 10.1128/MCB.06743-11. Epub 2012 May 7.

10.

Phosphatidylserine receptor BAI1 and apoptotic cells as new promoters of myoblast fusion.

Hochreiter-Hufford AE, Lee CS, Kinchen JM, Sokolowski JD, Arandjelovic S, Call JA, Klibanov AL, Yan Z, Mandell JW, Ravichandran KS.

Nature. 2013 May 9;497(7448):263-7. doi: 10.1038/nature12135. Epub 2013 Apr 24.

11.

PH domain of ELMO functions in trans to regulate Rac activation via Dock180.

Lu M, Kinchen JM, Rossman KL, Grimsley C, deBakker C, Brugnera E, Tosello-Trampont AC, Haney LB, Klingele D, Sondek J, Hengartner MO, Ravichandran KS.

Nat Struct Mol Biol. 2004 Aug;11(8):756-62. Epub 2004 Jul 11.

PMID:
15247908
12.

Engulfment of apoptotic cells in C. elegans is mediated by integrin alpha/SRC signaling.

Hsu TY, Wu YC.

Curr Biol. 2010 Mar 23;20(6):477-86. doi: 10.1016/j.cub.2010.01.062. Epub 2010 Mar 11.

13.

Nuclear localization of the DOCK180/ELMO complex.

Yin J, Haney L, Walk S, Zhou S, Ravichandran KS, Wang W.

Arch Biochem Biophys. 2004 Sep 1;429(1):23-9.

PMID:
15288806
14.

Unexpected requirement for ELMO1 in clearance of apoptotic germ cells in vivo.

Elliott MR, Zheng S, Park D, Woodson RI, Reardon MA, Juncadella IJ, Kinchen JM, Zhang J, Lysiak JJ, Ravichandran KS.

Nature. 2010 Sep 16;467(7313):333-7. doi: 10.1038/nature09356.

15.

The phosphatidylserine receptor TIM-4 does not mediate direct signaling.

Park D, Hochreiter-Hufford A, Ravichandran KS.

Curr Biol. 2009 Feb 24;19(4):346-51. doi: 10.1016/j.cub.2009.01.042. Epub 2009 Feb 12.

16.

Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12.

Wang X, Wu YC, Fadok VA, Lee MC, Gengyo-Ando K, Cheng LC, Ledwich D, Hsu PK, Chen JY, Chou BK, Henson P, Mitani S, Xue D.

Science. 2003 Nov 28;302(5650):1563-6.

17.

A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs.

Lu M, Kinchen JM, Rossman KL, Grimsley C, Hall M, Sondek J, Hengartner MO, Yajnik V, Ravichandran KS.

Curr Biol. 2005 Feb 22;15(4):371-7.

18.

Evidence for a conserved role for CRKII and Rac in engulfment of apoptotic cells.

Tosello-Trampont AC, Brugnera E, Ravichandran KS.

J Biol Chem. 2001 Apr 27;276(17):13797-802. Epub 2001 Jan 31.

19.

Brain angiogenesis inhibitor 1 (BAI1) is a pattern recognition receptor that mediates macrophage binding and engulfment of Gram-negative bacteria.

Das S, Owen KA, Ly KT, Park D, Black SG, Wilson JM, Sifri CD, Ravichandran KS, Ernst PB, Casanova JE.

Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):2136-41. doi: 10.1073/pnas.1014775108. Epub 2011 Jan 18.

20.

CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.

Gumienny TL, Brugnera E, Tosello-Trampont AC, Kinchen JM, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van Aelst L, Hengartner MO, Ravichandran KS.

Cell. 2001 Oct 5;107(1):27-41.

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