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Items: 1 to 20 of 119

1.

KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell cell junctions.

Glading A, Han J, Stockton RA, Ginsberg MH.

J Cell Biol. 2007 Oct 22;179(2):247-54.

2.

A mechanism of Rap1-induced stabilization of endothelial cell--cell junctions.

Liu JJ, Stockton RA, Gingras AR, Ablooglu AJ, Han J, Bobkov AA, Ginsberg MH.

Mol Biol Cell. 2011 Jul 15;22(14):2509-19. doi: 10.1091/mbc.E11-02-0157. Epub 2011 Jun 1.

3.

The structure of the ternary complex of Krev interaction trapped 1 (KRIT1) bound to both the Rap1 GTPase and the heart of glass (HEG1) cytoplasmic tail.

Gingras AR, Puzon-McLaughlin W, Ginsberg MH.

J Biol Chem. 2013 Aug 16;288(33):23639-49. doi: 10.1074/jbc.M113.462911. Epub 2013 Jun 27.

4.

Krit 1 interactions with microtubules and membranes are regulated by Rap1 and integrin cytoplasmic domain associated protein-1.

Béraud-Dufour S, Gautier R, Albiges-Rizo C, Chardin P, Faurobert E.

FEBS J. 2007 Nov;274(21):5518-32. Epub 2007 Oct 3.

5.

CCM1 regulates vascular-lumen organization by inducing endothelial polarity.

Lampugnani MG, Orsenigo F, Rudini N, Maddaluno L, Boulday G, Chapon F, Dejana E.

J Cell Sci. 2010 Apr 1;123(Pt 7):1073-80. doi: 10.1242/jcs.059329.

6.

Rap1 and its effector KRIT1/CCM1 regulate beta-catenin signaling.

Glading AJ, Ginsberg MH.

Dis Model Mech. 2010 Jan-Feb;3(1-2):73-83. doi: 10.1242/dmm.003293. Epub 2009 Dec 9.

7.

Structural basis for small G protein effector interaction of Ras-related protein 1 (Rap1) and adaptor protein Krev interaction trapped 1 (KRIT1).

Li X, Zhang R, Draheim KM, Liu W, Calderwood DA, Boggon TJ.

J Biol Chem. 2012 Jun 22;287(26):22317-27. doi: 10.1074/jbc.M112.361295. Epub 2012 May 10.

8.

Structural basis of the junctional anchorage of the cerebral cavernous malformations complex.

Gingras AR, Liu JJ, Ginsberg MH.

J Cell Biol. 2012 Oct 1;199(1):39-48. doi: 10.1083/jcb.201205109. Epub 2012 Sep 24.

10.

Role of afadin in vascular endothelial growth factor- and sphingosine 1-phosphate-induced angiogenesis.

Tawa H, Rikitake Y, Takahashi M, Amano H, Miyata M, Satomi-Kobayashi S, Kinugasa M, Nagamatsu Y, Majima T, Ogita H, Miyoshi J, Hirata K, Takai Y.

Circ Res. 2010 Jun 11;106(11):1731-42. doi: 10.1161/CIRCRESAHA.110.216747. Epub 2010 Apr 22.

11.

Cell-cell junction formation: the role of Rap1 and Rap1 guanine nucleotide exchange factors.

Pannekoek WJ, Kooistra MR, Zwartkruis FJ, Bos JL.

Biochim Biophys Acta. 2009 Apr;1788(4):790-6. doi: 10.1016/j.bbamem.2008.12.010. Epub 2008 Dec 29. Review.

12.

Epac1 regulates integrity of endothelial cell junctions through VE-cadherin.

Kooistra MR, Corada M, Dejana E, Bos JL.

FEBS Lett. 2005 Sep 12;579(22):4966-72.

13.

Endothelial barrier stabilization by a cyclic tandem peptide targeting VE-cadherin transinteraction in vitro and in vivo.

Heupel WM, Efthymiadis A, Schlegel N, Müller T, Baumer Y, Baumgartner W, Drenckhahn D, Waschke J.

J Cell Sci. 2009 May 15;122(Pt 10):1616-25. doi: 10.1242/jcs.040212.

14.

Cytoskeleton assembly at endothelial cell-cell contacts is regulated by alphaII-spectrin-VASP complexes.

Benz PM, Blume C, Moebius J, Oschatz C, Schuh K, Sickmann A, Walter U, Feller SM, Renné T.

J Cell Biol. 2008 Jan 14;180(1):205-19. doi: 10.1083/jcb.200709181.

15.

Neisseria meningitidis infection of human endothelial cells interferes with leukocyte transmigration by preventing the formation of endothelial docking structures.

Doulet N, Donnadieu E, Laran-Chich MP, Niedergang F, Nassif X, Couraud PO, Bourdoulous S.

J Cell Biol. 2006 May 22;173(4):627-37.

16.

Regulation of endothelial junctional permeability.

Vandenbroucke E, Mehta D, Minshall R, Malik AB.

Ann N Y Acad Sci. 2008 Mar;1123:134-45. doi: 10.1196/annals.1420.016. Review.

PMID:
18375586
17.

Functional analyses of human and zebrafish 18-amino acid in-frame deletion pave the way for domain mapping of the cerebral cavernous malformation 3 protein.

Voss K, Stahl S, Hogan BM, Reinders J, Schleider E, Schulte-Merker S, Felbor U.

Hum Mutat. 2009 Jun;30(6):1003-11. doi: 10.1002/humu.20996.

PMID:
19370760
18.

Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion.

Katagiri K, Imamura M, Kinashi T.

Nat Immunol. 2006 Sep;7(9):919-28. Epub 2006 Aug 6.

PMID:
16892067
19.

The role of VASP in regulation of cAMP- and Rac 1-mediated endothelial barrier stabilization.

Schlegel N, Burger S, Golenhofen N, Walter U, Drenckhahn D, Waschke J.

Am J Physiol Cell Physiol. 2008 Jan;294(1):C178-88. Epub 2007 Nov 7.

20.

Characterization of interactions of adapter protein RAPL/Nore1B with RAP GTPases and their role in T cell migration.

Miertzschke M, Stanley P, Bunney TD, Rodrigues-Lima F, Hogg N, Katan M.

J Biol Chem. 2007 Oct 19;282(42):30629-42. Epub 2007 Aug 23.

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