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Items: 1 to 20 of 110

1.

Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1.

Reid SP, Valmas C, Martinez O, Sanchez FM, Basler CF.

J Virol. 2007 Dec;81(24):13469-77. Epub 2007 Oct 10.

2.

Ebola virus VP24 binds karyopherin alpha1 and blocks STAT1 nuclear accumulation.

Reid SP, Leung LW, Hartman AL, Martinez O, Shaw ML, Carbonnelle C, Volchkov VE, Nichol ST, Basler CF.

J Virol. 2006 Jun;80(11):5156-67.

3.

Ebolavirus VP24 binding to karyopherins is required for inhibition of interferon signaling.

Mateo M, Reid SP, Leung LW, Basler CF, Volchkov VE.

J Virol. 2010 Jan;84(2):1169-75. doi: 10.1128/JVI.01372-09. Epub 2009 Nov 4.

4.

VP24-Karyopherin Alpha Binding Affinities Differ between Ebolavirus Species, Influencing Interferon Inhibition and VP24 Stability.

Schwarz TM, Edwards MR, Diederichs A, Alinger JB, Leung DW, Amarasinghe GK, Basler CF.

J Virol. 2017 Jan 31;91(4). pii: e01715-16. doi: 10.1128/JVI.01715-16. Print 2017 Feb 15.

5.

The Ebola virus VP24 protein prevents hnRNP C1/C2 binding to karyopherin α1 and partially alters its nuclear import.

Shabman RS, Gulcicek EE, Stone KL, Basler CF.

J Infect Dis. 2011 Nov;204 Suppl 3:S904-10. doi: 10.1093/infdis/jir323.

6.

Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1.

Xu W, Edwards MR, Borek DM, Feagins AR, Mittal A, Alinger JB, Berry KN, Yen B, Hamilton J, Brett TJ, Pappu RV, Leung DW, Basler CF, Amarasinghe GK.

Cell Host Microbe. 2014 Aug 13;16(2):187-200. doi: 10.1016/j.chom.2014.07.008.

7.

The ebola virus interferon antagonist VP24 directly binds STAT1 and has a novel, pyramidal fold.

Zhang AP, Bornholdt ZA, Liu T, Abelson DM, Lee DE, Li S, Woods VL Jr, Saphire EO.

PLoS Pathog. 2012 Feb;8(2):e1002550. doi: 10.1371/journal.ppat.1002550. Epub 2012 Feb 23. Erratum in: PLoS Pathog. 2013 Dec;9(12). doi:10.1371/annotation/360ddc68-0313-4eae-af24-043cc040c52d.

8.

Lloviu virus VP24 and VP35 proteins function as innate immune antagonists in human and bat cells.

Feagins AR, Basler CF.

Virology. 2015 Nov;485:145-52. doi: 10.1016/j.virol.2015.07.010. Epub 2015 Aug 6.

9.

Evasion of interferon responses by Ebola and Marburg viruses.

Basler CF, Amarasinghe GK.

J Interferon Cytokine Res. 2009 Sep;29(9):511-20. doi: 10.1089/jir.2009.0076. Review.

10.

An all-atom molecular dynamics study of the anti-interferon signaling of Ebola virus: interaction mechanisms of EBOV VP24 binding to Karyopherin alpha5.

Ding JN, Zhang YJ, Zhong H, Ao CC, Li J, Han JG.

Mol Biosyst. 2017 May 2;13(5):1031-1045. doi: 10.1039/c7mb00136c.

PMID:
28418440
11.

Conserved differences in protein sequence determine the human pathogenicity of Ebolaviruses.

Pappalardo M, Juliá M, Howard MJ, Rossman JS, Michaelis M, Wass MN.

Sci Rep. 2016 Mar 24;6:23743. doi: 10.1038/srep23743.

12.

Investigating Ebola virus pathogenicity using molecular dynamics.

Pappalardo M, Collu F, Macpherson J, Michaelis M, Fraternali F, Wass MN.

BMC Genomics. 2017 Aug 11;18(Suppl 5):566. doi: 10.1186/s12864-017-3912-2.

13.

Changes associated with Ebola virus adaptation to novel species.

Pappalardo M, Reddin IG, Cantoni D, Rossman JS, Michaelis M, Wass MN.

Bioinformatics. 2017 Jul 1;33(13):1911-1915. doi: 10.1093/bioinformatics/btx065.

PMID:
28200119
14.

Macrocyclic peptide inhibitors for the protein-protein interaction of Zaire Ebola virus protein 24 and karyopherin alpha 5.

Song X, Lu LY, Passioura T, Suga H.

Org Biomol Chem. 2017 Jun 21;15(24):5155-5160. doi: 10.1039/c7ob00012j.

PMID:
28574091
15.

Fold prediction of VP24 protein of Ebola and Marburg viruses using de novo fragment assembly.

Lee MS, Lebeda FJ, Olson MA.

J Struct Biol. 2009 Aug;167(2):136-44. doi: 10.1016/j.jsb.2009.05.001. Epub 2009 May 15.

PMID:
19447180
16.

Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane.

Frieman M, Yount B, Heise M, Kopecky-Bromberg SA, Palese P, Baric RS.

J Virol. 2007 Sep;81(18):9812-24. Epub 2007 Jun 27.

17.

In Silico Study of Plant Polyphenols' Interactions with VP24-Ebola Virus Membrane-associated Protein.

Pleško S, Volk H, Lukšič M, Podlipnik Č.

Acta Chim Slov. 2015;62(3):555-64.

PMID:
26454589
18.

3Cpro of foot-and-mouth disease virus antagonizes the interferon signaling pathway by blocking STAT1/STAT2 nuclear translocation.

Du Y, Bi J, Liu J, Liu X, Wu X, Jiang P, Yoo D, Zhang Y, Wu J, Wan R, Zhao X, Guo L, Sun W, Cong X, Chen L, Wang J.

J Virol. 2014 May;88(9):4908-20. doi: 10.1128/JVI.03668-13. Epub 2014 Feb 19.

19.

Importin-α7 Is Involved in the Formation of Ebola Virus Inclusion Bodies but Is Not Essential for Pathogenicity in Mice.

Gabriel G, Feldmann F, Reimer R, Thiele S, Fischer M, Hartmann E, Bader M, Ebihara H, Hoenen T, Feldmann H.

J Infect Dis. 2015 Oct 1;212 Suppl 2:S316-21. doi: 10.1093/infdis/jiv240. Epub 2015 Jul 16.

20.

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