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Items: 1 to 20 of 115

1.

Cyclic AMP regulates bicarbonate secretion in cholangiocytes through release of ATP into bile.

Minagawa N, Nagata J, Shibao K, Masyuk AI, Gomes DA, Rodrigues MA, Lesage G, Akiba Y, Kaunitz JD, Ehrlich BE, Larusso NF, Nathanson MH.

Gastroenterology. 2007 Nov;133(5):1592-602.

2.

Polarized expression and function of P2Y ATP receptors in rat bile duct epithelia.

Dranoff JA, Masyuk AI, Kruglov EA, LaRusso NF, Nathanson MH.

Am J Physiol Gastrointest Liver Physiol. 2001 Oct;281(4):G1059-67.

3.

The alpha2-adrenergic receptor agonist UK 14,304 inhibits secretin-stimulated ductal secretion by downregulation of the cAMP system in bile duct-ligated rats.

Francis H, LeSage G, DeMorrow S, Alvaro D, Ueno Y, Venter J, Glaser S, Mancino MG, Marucci L, Benedetti A, Alpini G.

Am J Physiol Cell Physiol. 2007 Oct;293(4):C1252-62.

4.

Alpha-1 adrenergic receptor agonists modulate ductal secretion of BDL rats via Ca(2+)- and PKC-dependent stimulation of cAMP.

LeSage GD, Alvaro D, Glaser S, Francis H, Marucci L, Roskams T, Phinizy JL, Marzioni M, Benedetti A, Taffetani S, Barbaro B, Fava G, Ueno Y, Alpini G.

Hepatology. 2004 Nov;40(5):1116-27.

PMID:
15486932
5.

Ursodeoxycholic acid stimulates cholangiocyte fluid secretion in mice via CFTR-dependent ATP secretion.

Fiorotto R, Spirlì C, Fabris L, Cadamuro M, Okolicsanyi L, Strazzabosco M.

Gastroenterology. 2007 Nov;133(5):1603-13.

PMID:
17983806
6.

Cholangiocyte cilia express TRPV4 and detect changes in luminal tonicity inducing bicarbonate secretion.

Gradilone SA, Masyuk AI, Splinter PL, Banales JM, Huang BQ, Tietz PS, Masyuk TV, Larusso NF.

Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):19138-43.

7.

Role and mechanisms of action of acetylcholine in the regulation of rat cholangiocyte secretory functions.

Alvaro D, Alpini G, Jezequel AM, Bassotti C, Francia C, Fraioli F, Romeo R, Marucci L, Le Sage G, Glaser SS, Benedetti A.

J Clin Invest. 1997 Sep 15;100(6):1349-62. Erratum in: J Clin Invest 1997 Oct 15;100(8):following 2139.

8.

Bile duct epithelia regulate biliary bicarbonate excretion in normal rat liver.

Hirata K, Nathanson MH.

Gastroenterology. 2001 Aug;121(2):396-406.

PMID:
11487549
9.

Correction of CFTR malfunction and stimulation of Ca-activated Cl channels restore HCO3- secretion in cystic fibrosis bile ductular cells.

Zsembery A, Jessner W, Sitter G, SpirlĂ­ C, Strazzabosco M, Graf J.

Hepatology. 2002 Jan;35(1):95-104.

PMID:
11786964
10.

Somatostatin stimulates ductal bile absorption and inhibits ductal bile secretion in mice via SSTR2 on cholangiocytes.

Gong AY, Tietz PS, Muff MA, Splinter PL, Huebert RC, Strowski MZ, Chen XM, LaRusso NF.

Am J Physiol Cell Physiol. 2003 May;284(5):C1205-14.

11.

Morphological, molecular, and functional heterogeneity of cholangiocytes from normal rat liver.

Alpini G, Roberts S, Kuntz SM, Ueno Y, Gubba S, Podila PV, LeSage G, LaRusso NF.

Gastroenterology. 1996 May;110(5):1636-43.

PMID:
8613073
12.

cAMP/protein kinase A activates cystic fibrosis transmembrane conductance regulator for ATP release from rat skeletal muscle during low pH or contractions.

Tu J, Lu L, Cai W, Ballard HJ.

PLoS One. 2012;7(11):e50157. doi: 10.1371/journal.pone.0050157. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/bca273e5-7448-4773-a4e4-fe538be554da.

13.

Loss of inositol 1,4,5-trisphosphate receptors from bile duct epithelia is a common event in cholestasis.

Shibao K, Hirata K, Robert ME, Nathanson MH.

Gastroenterology. 2003 Oct;125(4):1175-87.

14.

Large but not small intrahepatic bile ducts are involved in secretin-regulated ductal bile secretion.

Alpini G, Glaser S, Robertson W, Rodgers RE, Phinizy JL, Lasater J, LeSage GD.

Am J Physiol. 1997 May;272(5 Pt 1):G1064-74.

PMID:
9176215
15.

Endothelin-1 inhibits secretin-stimulated ductal secretion by interacting with ETA receptors on large cholangiocytes.

Caligiuri A, Glaser S, Rodgers RE, Phinizy JL, Robertson W, Papa E, Pinzani M, Alpini G.

Am J Physiol. 1998 Oct;275(4 Pt 1):G835-46.

16.

Thinking outside the cell: the role of extracellular adenosine triphosphate in bile formation.

Feranchak AP, Fitz JG.

Gastroenterology. 2007 Nov;133(5):1726-8. No abstract available.

PMID:
17983816
17.

Regulation of Ca(2+) signaling in rat bile duct epithelia by inositol 1,4,5-trisphosphate receptor isoforms.

Hirata K, Dufour JF, Shibao K, Knickelbein R, O'Neill AF, Bode HP, Cassio D, St-Pierre MV, Larusso NF, Leite MF, Nathanson MH.

Hepatology. 2002 Aug;36(2):284-96.

18.

Water movement across rat bile duct units is transcellular and channel-mediated.

Cova E, Gong A, Marinelli RA, LaRusso NF.

Hepatology. 2001 Sep;34(3):456-63.

PMID:
11526529
19.

Gastrin inhibits secretin-induced ductal secretion by interaction with specific receptors on rat cholangiocytes.

Glaser SS, Rodgers RE, Phinizy JL, Robertson WE, Lasater J, Caligiuri A, Tretjak Z, LeSage GD, Alpini G.

Am J Physiol. 1997 Nov;273(5 Pt 1):G1061-70.

20.

Dopaminergic inhibition of secretin-stimulated choleresis by increased PKC-gamma expression and decrease of PKA activity.

Glaser S, Alvaro D, Roskams T, Phinizy JL, Stoica G, Francis H, Ueno Y, Barbaro B, Marzioni M, Mauldin J, Rashid S, Mancino MG, LeSage G, Alpini G.

Am J Physiol Gastrointest Liver Physiol. 2003 Apr;284(4):G683-94.

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