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Items: 1 to 20 of 60

1.

Compromised intestinal lipid absorption in mice with a liver-specific deficiency of liver receptor homolog 1.

Mataki C, Magnier BC, Houten SM, Annicotte JS, Argmann C, Thomas C, Overmars H, Kulik W, Metzger D, Auwerx J, Schoonjans K.

Mol Cell Biol. 2007 Dec;27(23):8330-9. Epub 2007 Oct 1.

2.

Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis.

Lee YK, Schmidt DR, Cummins CL, Choi M, Peng L, Zhang Y, Goodwin B, Hammer RE, Mangelsdorf DJ, Kliewer SA.

Mol Endocrinol. 2008 Jun;22(6):1345-56. doi: 10.1210/me.2007-0565. Epub 2008 Mar 6.

3.

Liver receptor homolog-1 is critical for adequate up-regulation of Cyp7a1 gene transcription and bile salt synthesis during bile salt sequestration.

Out C, Hageman J, Bloks VW, Gerrits H, Sollewijn Gelpke MD, Bos T, Havinga R, Smit MJ, Kuipers F, Groen AK.

Hepatology. 2011 Jun;53(6):2075-85. doi: 10.1002/hep.24286.

PMID:
21391220
4.

Studies on LXR- and FXR-mediated effects on cholesterol homeostasis in normal and cholic acid-depleted mice.

Wang J, Einarsson C, Murphy C, Parini P, Björkhem I, Gåfvels M, Eggertsen G.

J Lipid Res. 2006 Feb;47(2):421-30. Epub 2005 Nov 1.

5.

Muricholic bile acids are potent regulators of bile acid synthesis via a positive feedback mechanism.

Hu X, Bonde Y, Eggertsen G, Rudling M.

J Intern Med. 2014 Jan;275(1):27-38. doi: 10.1111/joim.12140. Epub 2013 Oct 11. Erratum in: J Intern Med. 2015 Jul;278(1):97.

6.

Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine.

Kim I, Ahn SH, Inagaki T, Choi M, Ito S, Guo GL, Kliewer SA, Gonzalez FJ.

J Lipid Res. 2007 Dec;48(12):2664-72. Epub 2007 Aug 24.

7.

Diverse effects of oats on cholesterol metabolism in C57BL/6 mice correlate with expression of hepatic bile acid-producing enzymes.

Andersson KE, Axling U, Xu J, Swärd K, Ahrné S, Molin G, Holm C, Hellstrand P.

Eur J Nutr. 2013 Oct;52(7):1755-69. doi: 10.1007/s00394-012-0479-1. Epub 2012 Dec 21.

PMID:
23262749
8.

Decreased bile-acid synthesis in livers of hepatocyte-conditional NADPH-cytochrome P450 reductase-null mice results in increased bile acids in serum.

Cheng X, Zhang Y, Klaassen CD.

J Pharmacol Exp Ther. 2014 Oct;351(1):105-13. doi: 10.1124/jpet.114.216796. Epub 2014 Jul 17.

9.

Differential hepatocellular zonation pattern of cholesterol 7alpha-hydroxylase (Cyp7a1) and sterol 12alpha-hydroxylase (Cyp8b1) in the mouse.

Wang J, Olin M, Rozell B, Björkhem I, Einarsson C, Eggertsen G, Gåfvels M.

Histochem Cell Biol. 2007 Mar;127(3):253-61. Epub 2007 Jan 20.

PMID:
17237956
10.

Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis.

Sanyal S, Båvner A, Haroniti A, Nilsson LM, Lundåsen T, Rehnmark S, Witt MR, Einarsson C, Talianidis I, Gustafsson JA, Treuter E.

Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15665-70. Epub 2007 Sep 25.

11.

Comparative regulation of major enzymes in the bile acid biosynthesis pathway by cholesterol, cholate and taurine in mice and rats.

Chen W, Suruga K, Nishimura N, Gouda T, Lam VN, Yokogoshi H.

Life Sci. 2005 Jul 1;77(7):746-57. Epub 2005 Mar 19.

PMID:
15936349
12.

Resistance of SHP-null mice to bile acid-induced liver damage.

Wang L, Han Y, Kim CS, Lee YK, Moore DD.

J Biol Chem. 2003 Nov 7;278(45):44475-81. Epub 2003 Aug 21.

13.

Species-specific mechanisms for cholesterol 7alpha-hydroxylase (CYP7A1) regulation by drugs and bile acids.

Handschin C, Gnerre C, Fraser DJ, Martinez-Jimenez C, Jover R, Meyer UA.

Arch Biochem Biophys. 2005 Feb 1;434(1):75-85.

PMID:
15629111
14.

Tumor suppressor p53 regulates bile acid homeostasis via small heterodimer partner.

Kim DH, Lee JW.

Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12266-70. doi: 10.1073/pnas.1019678108. Epub 2011 Jul 11.

15.

Regulation of cholesterol-7alpha-hydroxylase: BAREly missing a SHP.

Davis RA, Miyake JH, Hui TY, Spann NJ.

J Lipid Res. 2002 Apr;43(4):533-43. Review.

16.

Increased cholesterol 7alpha-hydroxylase expression and size of the bile acid pool in the lactating rat.

Wooton-Kee CR, Cohen DE, Vore M.

Am J Physiol Gastrointest Liver Physiol. 2008 Apr;294(4):G1009-16. doi: 10.1152/ajpgi.00017.2008. Epub 2008 Feb 21.

17.

Enterohepatic circulation of bile salts in farnesoid X receptor-deficient mice: efficient intestinal bile salt absorption in the absence of ileal bile acid-binding protein.

Kok T, Hulzebos CV, Wolters H, Havinga R, Agellon LB, Stellaard F, Shan B, Schwarz M, Kuipers F.

J Biol Chem. 2003 Oct 24;278(43):41930-7. Epub 2003 Aug 12.

18.

Cholic acid as key regulator of cholesterol synthesis, intestinal absorption and hepatic storage in mice.

Murphy C, Parini P, Wang J, Björkhem I, Eggertsen G, Gåfvels M.

Biochim Biophys Acta. 2005 Aug 15;1735(3):167-75.

PMID:
15994119
20.

Dexamethasone exposure of neonatal rats modulates biliary lipid secretion and hepatic expression of genes controlling bile acid metabolism in adulthood without interfering with primary bile acid kinetics.

Liu Y, Havinga R, VAN DER Leij FR, Boverhof R, Sauer PJ, Kuipers F, Stellaard F.

Pediatr Res. 2008 Apr;63(4):375-81. doi: 10.1203/PDR.0b013e318165b8af.

PMID:
18356742

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