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Items: 1 to 20 of 97

1.

Foxa2 controls vesicle docking and insulin secretion in mature Beta cells.

Gao N, White P, Doliba N, Golson ML, Matschinsky FM, Kaestner KH.

Cell Metab. 2007 Oct;6(4):267-79.

2.

Conditional Tissue-Specific Foxa2 Ablation in Mouse Pancreas Causes Hyperinsulinemic Hypoglycemia.

Wu Z, Fei A, Liu Y, Pan S.

Am J Ther. 2016 Nov/Dec;23(6):e1442-e1448.

PMID:
26882312
3.

Foxa2 (HNF3beta ) controls multiple genes implicated in metabolism-secretion coupling of glucose-induced insulin release.

Wang H, Gauthier BR, Hagenfeldt-Johansson KA, Iezzi M, Wollheim CB.

J Biol Chem. 2002 May 17;277(20):17564-70. Epub 2002 Mar 1.

4.

MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines.

Baroukh N, Ravier MA, Loder MK, Hill EV, Bounacer A, Scharfmann R, Rutter GA, Van Obberghen E.

J Biol Chem. 2007 Jul 6;282(27):19575-88. Epub 2007 Apr 26.

6.

Foxa2 is required for the differentiation of pancreatic alpha-cells.

Lee CS, Sund NJ, Behr R, Herrera PL, Kaestner KH.

Dev Biol. 2005 Feb 15;278(2):484-95.

7.

Beta-cell PDE3B regulates Ca2+-stimulated exocytosis of insulin.

Walz HA, Wierup N, Vikman J, Manganiello VC, Degerman E, Eliasson L, Holst LS.

Cell Signal. 2007 Jul;19(7):1505-13. Epub 2007 Feb 12.

PMID:
17368848
8.

Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cell.

Gao N, Le Lay J, Qin W, Doliba N, Schug J, Fox AJ, Smirnova O, Matschinsky FM, Kaestner KH.

Mol Endocrinol. 2010 Aug;24(8):1594-604. doi: 10.1210/me.2009-0513. Epub 2010 Jun 9.

9.

Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.

Gao N, LeLay J, Vatamaniuk MZ, Rieck S, Friedman JR, Kaestner KH.

Genes Dev. 2008 Dec 15;22(24):3435-48. doi: 10.1101/gad.1752608.

10.

Glucose-induced cyclic AMP oscillations regulate pulsatile insulin secretion.

Dyachok O, Idevall-Hagren O, Sågetorp J, Tian G, Wuttke A, Arrieumerlou C, Akusjärvi G, Gylfe E, Tengholm A.

Cell Metab. 2008 Jul;8(1):26-37. doi: 10.1016/j.cmet.2008.06.003.

11.

Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice.

Gustavsson N, Lao Y, Maximov A, Chuang JC, Kostromina E, Repa JJ, Li C, Radda GK, Südhof TC, Han W.

Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3992-7. doi: 10.1073/pnas.0711700105. Epub 2008 Feb 28.

12.

Tissue-specific deletion of Foxa2 in pancreatic beta cells results in hyperinsulinemic hypoglycemia.

Sund NJ, Vatamaniuk MZ, Casey M, Ang SL, Magnuson MA, Stoffers DA, Matschinsky FM, Kaestner KH.

Genes Dev. 2001 Jul 1;15(13):1706-15.

13.

TRPM4 controls insulin secretion in pancreatic beta-cells.

Cheng H, Beck A, Launay P, Gross SA, Stokes AJ, Kinet JP, Fleig A, Penner R.

Cell Calcium. 2007 Jan;41(1):51-61. Epub 2006 Jun 27.

PMID:
16806463
14.

Exocytotic properties of human pancreatic beta-cells.

Braun M, Ramracheya R, Johnson PR, Rorsman P.

Ann N Y Acad Sci. 2009 Jan;1152:187-93. doi: 10.1111/j.1749-6632.2008.03992.x.

PMID:
19161389
15.

INGAP-PP up-regulates the expression of genes and proteins related to K+ ATP channels and ameliorates Ca2+ handling in cultured adult rat islets.

Silva KE, Barbosa HC, Rafacho A, Bosqueiro JR, Stoppiglia LF, Carneiro EM, Borelli MI, Del Zotto H, Gagliardino JJ, Boschero AC.

Regul Pept. 2008 Jun 5;148(1-3):39-45. doi: 10.1016/j.regpep.2008.02.008. Epub 2008 Mar 4.

PMID:
18378016
16.

Insulin secretion in islets from mice with a double knockout for the dense core vesicle proteins islet antigen-2 (IA-2) and IA-2beta.

Henquin JC, Nenquin M, Szollosi A, Kubosaki A, Notkins AL.

J Endocrinol. 2008 Mar;196(3):573-81. doi: 10.1677/JOE-07-0496.

17.

CAPS1 and CAPS2 regulate stability and recruitment of insulin granules in mouse pancreatic beta cells.

Speidel D, Salehi A, Obermueller S, Lundquist I, Brose N, Renström E, Rorsman P.

Cell Metab. 2008 Jan;7(1):57-67. doi: 10.1016/j.cmet.2007.11.009.

18.

A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis.

Fex M, Haemmerle G, Wierup N, Dekker-Nitert M, Rehn M, Ristow M, Zechner R, Sundler F, Holm C, Eliasson L, Mulder H.

Diabetologia. 2009 Feb;52(2):271-80. doi: 10.1007/s00125-008-1191-9. Epub 2008 Nov 21.

PMID:
19023560
19.

Mutated ATP synthase induces oxidative stress and impaired insulin secretion in beta-cells of female BHE/cdb rats.

Saleh MC, Fatehi-Hassanabad Z, Wang R, Nino-Fong R, Wadowska DW, Wright GM, Harper ME, Chan CB.

Diabetes Metab Res Rev. 2008 Jul-Aug;24(5):392-403. doi: 10.1002/dmrr.819.

PMID:
18273840
20.

A mouse line expressing Foxa2-driven Cre recombinase in node, notochord, floorplate, and endoderm.

Uetzmann L, Burtscher I, Lickert H.

Genesis. 2008 Oct;46(10):515-22. doi: 10.1002/dvg.20410.

PMID:
18798232

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