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A randomised controlled trial examining the longer-term outcomes of standard versus new antiepileptic drugs. The SANAD trial.

Marson AG, Appleton R, Baker GA, Chadwick DW, Doughty J, Eaton B, Gamble C, Jacoby A, Shackley P, Smith DF, Tudur-Smith C, Vanoli A, Williamson PR.

Health Technol Assess. 2007 Oct;11(37):iii-iv, ix-x, 1-134.


Clinical effectiveness, tolerability and cost-effectiveness of newer drugs for epilepsy in adults: a systematic review and economic evaluation.

Wilby J, Kainth A, Hawkins N, Epstein D, McIntosh H, McDaid C, Mason A, Golder S, O'Meara S, Sculpher M, Drummond M, Forbes C.

Health Technol Assess. 2005 Apr;9(15):1-157, iii-iv. Review.


Prognostic factors for time to treatment failure and time to 12 months of remission for patients with focal epilepsy: post-hoc, subgroup analyses of data from the SANAD trial.

Bonnett L, Smith CT, Smith D, Williamson P, Chadwick D, Marson AG.

Lancet Neurol. 2012 Apr;11(4):331-40. doi: 10.1016/S1474-4422(12)70018-2. Epub 2012 Feb 28.


Topiramate versus carbamazepine monotherapy for epilepsy: an individual participant data review.

Nolan SJ, Sudell M, Tudur Smith C, Marson AG.

Cochrane Database Syst Rev. 2016 Dec 6;12:CD012065. doi: 10.1002/14651858.CD012065.pub2. Review.


Comparative Long-Term Effectiveness of a Monotherapy with Five Antiepileptic Drugs for Focal Epilepsy in Adult Patients: A Prospective Cohort Study.

Zeng QY, Fan TT, Zhu P, He RQ, Bao YX, Zheng RY, Xu HQ.

PLoS One. 2015 Jul 6;10(7):e0131566. doi: 10.1371/journal.pone.0131566. eCollection 2015.


Pregabalin monotherapy for epilepsy.

Zhou Q, Zheng J, Yu L, Jia X.

Cochrane Database Syst Rev. 2012 Oct 17;10:CD009429. doi: 10.1002/14651858.CD009429.pub2. Review.


Lamotrigine versus carbamazepine monotherapy for epilepsy: an individual participant data review.

Nolan SJ, Tudur Smith C, Weston J, Marson AG.

Cochrane Database Syst Rev. 2016 Nov 14;11:CD001031. Review.


The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial.

Marson AG, Al-Kharusi AM, Alwaidh M, Appleton R, Baker GA, Chadwick DW, Cramp C, Cockerell OC, Cooper PN, Doughty J, Eaton B, Gamble C, Goulding PJ, Howell SJ, Hughes A, Jackson M, Jacoby A, Kellett M, Lawson GR, Leach JP, Nicolaides P, Roberts R, Shackley P, Shen J, Smith DF, Smith PE, Smith CT, Vanoli A, Williamson PR; SANAD Study group.

Lancet. 2007 Mar 24;369(9566):1016-26.


KOMET: an unblinded, randomised, two parallel-group, stratified trial comparing the effectiveness of levetiracetam with controlled-release carbamazepine and extended-release sodium valproate as monotherapy in patients with newly diagnosed epilepsy.

Trinka E, Marson AG, Van Paesschen W, Kälviäinen R, Marovac J, Duncan B, Buyle S, Hallström Y, Hon P, Muscas GC, Newton M, Meencke HJ, Smith PE, Pohlmann-Eden B; KOMET Study Group.

J Neurol Neurosurg Psychiatry. 2013 Oct;84(10):1138-47. doi: 10.1136/jnnp-2011-300376. Epub 2012 Aug 29.


Long-term retention rates of lamotrigine, gabapentin, and topiramate in chronic epilepsy.

Lhatoo SD, Wong IC, Polizzi G, Sander JW.

Epilepsia. 2000 Dec;41(12):1592-6.


New onset geriatric epilepsy: a randomized study of gabapentin, lamotrigine, and carbamazepine.

Rowan AJ, Ramsay RE, Collins JF, Pryor F, Boardman KD, Uthman BM, Spitz M, Frederick T, Towne A, Carter GS, Marks W, Felicetta J, Tomyanovich ML; VA Cooperative Study 428 Group.

Neurology. 2005 Jun 14;64(11):1868-73.


Novel anticonvulsant drugs.

Stefan H, Feuerstein TJ.

Pharmacol Ther. 2007 Jan;113(1):165-83. Epub 2006 Oct 9. Review.


Cross-reactivity of skin rashes with current antiepileptic drugs in Chinese population.

Wang XQ, Lang SY, Shi XB, Tian HJ, Wang RF, Yang F.

Seizure. 2010 Nov;19(9):562-6. doi: 10.1016/j.seizure.2010.09.003.


Long-term Effectiveness of Antiepileptic Drug Monotherapy in Partial Epileptic Patients: A 7-year Study in an Epilepsy Center in China.

Zhu F, Lang SY, Wang XQ, Shi XB, Ma YF, Zhang X, Chen YN, Zhang JT.

Chin Med J (Engl). 2015 Nov 20;128(22):3015-22. doi: 10.4103/0366-6999.168968.


The new antiepileptic drugs: a systematic review of their efficacy and tolerability.

Marson AG, Kadir ZA, Hutton JL, Chadwick DW.

Epilepsia. 1997 Aug;38(8):859-80.


The longer-term cognitive effects of adjunctive antiepileptic treatment with lacosamide in comparison with lamotrigine and topiramate in a naturalistic outpatient setting.

Helmstaedter C, Witt JA.

Epilepsy Behav. 2013 Feb;26(2):182-7. doi: 10.1016/j.yebeh.2012.11.052. Epub 2013 Jan 11.


Immediate-release versus controlled-release carbamazepine in the treatment of epilepsy.

Powell G, Saunders M, Marson AG.

Cochrane Database Syst Rev. 2010 Jan 20;(1):CD007124. doi: 10.1002/14651858.CD007124.pub2. Review. Update in: Cochrane Database Syst Rev. 2014;2:CD007124.


The LaLiMo Trial: lamotrigine compared with levetiracetam in the initial 26 weeks of monotherapy for focal and generalised epilepsy--an open-label, prospective, randomised controlled multicenter study.

Rosenow F, Schade-Brittinger C, Burchardi N, Bauer S, Klein KM, Weber Y, Lerche H, Evers S, Kovac S, Hallmeyer-Elgner S, Winkler G, Springub J, Niedhammer M, Roth E, Eisensehr I, Berrouschot J, Arnold S, Schröder M, Beige A, Oertel WH, Strzelczyk A, Haag A, Reif PS, Hamer HM; LaLiMo Study Group.

J Neurol Neurosurg Psychiatry. 2012 Nov;83(11):1093-8. doi: 10.1136/jnnp-2011-301999. Epub 2012 May 17.


Carbamazepine versus phenobarbitone monotherapy for epilepsy: an individual participant data review.

Nolan SJ, Marson AG, Weston J, Tudur Smith C.

Cochrane Database Syst Rev. 2015 Jul 23;(7):CD001904. doi: 10.1002/14651858.CD001904.pub2. Review. Update in: Cochrane Database Syst Rev. 2016 Dec 15;12 :CD001904.


Conversion from carbamazepine or oxcarbazepine to topiramate in adolescents and adults with epilepsy.

Kowalik A, Rimpau W, Adam H, Kühn F, van Oene J, Schreiner A, Bogdanow M, Schauble B; TOPMAT-EPY-405 investigators.

Acta Neurol Scand. 2008 Mar;117(3):159-66. doi: 10.1111/j.1600-0404.2007.00977.x. Epub 2008 Jan 23.


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