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Items: 1 to 20 of 113

1.

Alterations in cGMP, soluble guanylate cyclase, phosphodiesterase 5, and B-type natriuretic peptide induced by chronic increased pulmonary blood flow in lambs.

Oishi P, Sharma S, Grobe A, Azakie A, Harmon C, Johengen MJ, Hsu JH, Fratz S, Black SM, Fineman JR.

Pediatr Pulmonol. 2007 Nov;42(11):1057-71.

PMID:
17902145
2.

sGC and PDE5 are elevated in lambs with increased pulmonary blood flow and pulmonary hypertension.

Black SM, Sanchez LS, Mata-Greenwood E, Bekker JM, Steinhorn RH, Fineman JR.

Am J Physiol Lung Cell Mol Physiol. 2001 Nov;281(5):L1051-7.

3.

Inhaled nitric oxide decreases pulmonary soluble guanylate cyclase protein levels in 1-month-old lambs.

Thelitz S, Bekker JM, Ovadia B, Stuart RB, Johengen MJ, Black SM, Fineman JR.

J Thorac Cardiovasc Surg. 2004 May;127(5):1285-92.

4.

Endothelial alterations during inhaled NO in lambs with pulmonary hypertension: implications for rebound hypertension.

Ross GA, Oishi P, Azakie A, Fratz S, Fitzgerald RK, Johengen MJ, Harmon C, Hendricks-Munoz K, Xu J, Black SM, Fineman JR.

Am J Physiol Lung Cell Mol Physiol. 2005 Jan;288(1):L27-35. Epub 2004 Sep 3.

5.

Expression of VEGF and its receptors Flt-1 and Flk-1/KDR is altered in lambs with increased pulmonary blood flow and pulmonary hypertension.

Mata-Greenwood E, Meyrick B, Soifer SJ, Fineman JR, Black SM.

Am J Physiol Lung Cell Mol Physiol. 2003 Jul;285(1):L222-31. Epub 2003 Mar 28.

6.
7.

Hydrocortisone normalizes oxygenation and cGMP regulation in lambs with persistent pulmonary hypertension of the newborn.

Perez M, Lakshminrusimha S, Wedgwood S, Czech L, Gugino SF, Russell JA, Farrow KN, Steinhorn RH.

Am J Physiol Lung Cell Mol Physiol. 2012 Mar 15;302(6):L595-603. doi: 10.1152/ajplung.00145.2011. Epub 2011 Dec 23.

8.

In utero placement of aortopulmonary shunts. A model of postnatal pulmonary hypertension with increased pulmonary blood flow in lambs.

Reddy VM, Meyrick B, Wong J, Khoor A, Liddicoat JR, Hanley FL, Fineman JR.

Circulation. 1995 Aug 1;92(3):606-13.

9.

Pulmonary hypertension alters soluble guanylate cyclase activity and expression in pulmonary arteries isolated from fetal lambs.

Tzao C, Nickerson PA, Russell JA, Gugino SF, Steinhorn RH.

Pediatr Pulmonol. 2001 Feb;31(2):97-105.

PMID:
11180684
10.

Pulmonary vascular dysfunction in preterm lambs with chronic lung disease.

Bland RD, Ling CY, Albertine KH, Carlton DP, MacRitchie AJ, Day RW, Dahl MJ.

Am J Physiol Lung Cell Mol Physiol. 2003 Jul;285(1):L76-85. Epub 2003 Mar 7.

11.

Chronic pulmonary hypertension increases fetal lung cGMP phosphodiesterase activity.

Hanson KA, Ziegler JW, Rybalkin SD, Miller JW, Abman SH, Clarke WR.

Am J Physiol. 1998 Nov;275(5 Pt 1):L931-41.

12.

Pulmonary vascular effects of nitric oxide-cGMP augmentation in a model of chronic pulmonary hypertension in fetal and neonatal sheep.

Deruelle P, Grover TR, Abman SH.

Am J Physiol Lung Cell Mol Physiol. 2005 Nov;289(5):L798-806. Epub 2005 Jun 17.

13.

Cyclic GMP-specific phosphodiesterase 5 regulates growth and apoptosis in pulmonary endothelial cells.

Zhu B, Strada S, Stevens T.

Am J Physiol Lung Cell Mol Physiol. 2005 Aug;289(2):L196-206. Epub 2005 Mar 25.

14.

SOD and inhaled nitric oxide normalize phosphodiesterase 5 expression and activity in neonatal lambs with persistent pulmonary hypertension.

Farrow KN, Lakshminrusimha S, Czech L, Groh BS, Gugino SF, Davis JM, Russell JA, Steinhorn RH.

Am J Physiol Lung Cell Mol Physiol. 2010 Jul;299(1):L109-16. doi: 10.1152/ajplung.00309.2009. Epub 2010 Apr 16.

15.
16.

Altered endothelium-dependent relaxations in lambs with high pulmonary blood flow and pulmonary hypertension.

Steinhorn RH, Russell JA, Lakshminrusimha S, Gugino SF, Black SM, Fineman JR.

Am J Physiol Heart Circ Physiol. 2001 Jan;280(1):H311-7.

17.

Altered regulation of the ET-1 cascade in lambs with increased pulmonary blood flow and pulmonary hypertension.

Black SM, Bekker JM, Johengen MJ, Parry AJ, Soifer SJ, Fineman JR.

Pediatr Res. 2000 Jan;47(1):97-106.

PMID:
10625089
18.

Increased pulmonary blood flow does not alter surfactant protein gene expression in lambs within the first week of life.

Lee JW, Ovadia B, Azakie A, Salas S, Goerke J, Fineman JR, Gutierrez JA.

Am J Physiol Lung Cell Mol Physiol. 2004 Jun;286(6):L1237-43. Epub 2004 Jan 29.

19.

Negative functional effects of natriuretic peptides are attenuated in hypertrophic cardiac myocytes by reduced particulate guanylyl cyclase activity.

Meyer M, Zhang Q, Khurana K, Scholz PM, Weiss HR.

J Cardiovasc Pharmacol. 2007 Feb;49(2):100-5.

PMID:
17312451
20.

Decreased surfactant proteins in lambs with pulmonary hypertension secondary to increased blood flow.

Gutierrez JA, Parry AJ, McMullan DM, Chapin CJ, Fineman JR.

Am J Physiol Lung Cell Mol Physiol. 2001 Nov;281(5):L1264-70.

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