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Items: 1 to 20 of 254

1.

Detection of MDM2-CDK4 amplification by fluorescence in situ hybridization in 200 paraffin-embedded tumor samples: utility in diagnosing adipocytic lesions and comparison with immunohistochemistry and real-time PCR.

Sirvent N, Coindre JM, Maire G, Hostein I, Keslair F, Guillou L, Ranchere-Vince D, Terrier P, Pedeutour F.

Am J Surg Pathol. 2007 Oct;31(10):1476-89.

PMID:
17895748
2.

Detection of MDM2/CDK4 amplification in lipomatous soft tissue tumors from formalin-fixed, paraffin-embedded tissue: comparison of multiplex ligation-dependent probe amplification (MLPA) and fluorescence in situ hybridization (FISH).

Creytens D, van Gorp J, Ferdinande L, Speel EJ, Libbrecht L.

Appl Immunohistochem Mol Morphol. 2015 Feb;23(2):126-33. doi: 10.1097/PDM.0000000000000041.

PMID:
25679065
3.

The value of MDM2 and CDK4 amplification levels using real-time polymerase chain reaction for the differential diagnosis of liposarcomas and their histologic mimickers.

Shimada S, Ishizawa T, Ishizawa K, Matsumura T, Hasegawa T, Hirose T.

Hum Pathol. 2006 Sep;37(9):1123-9. Epub 2006 Jul 7.

PMID:
16938516
4.

Sensitivity of MDM2 amplification and unexpected multiple faint alphoid 12 (alpha 12 satellite sequences) signals in atypical lipomatous tumor.

Kashima T, Halai D, Ye H, Hing SN, Delaney D, Pollock R, O'Donnell P, Tirabosco R, Flanagan AM.

Mod Pathol. 2012 Oct;25(10):1384-96. doi: 10.1038/modpathol.2012.90. Epub 2012 Jun 15.

5.

Fluorescence in situ hybridization for MDM2 gene amplification as a diagnostic tool in lipomatous neoplasms.

Weaver J, Downs-Kelly E, Goldblum JR, Turner S, Kulkarni S, Tubbs RR, Rubin BP, Skacel M.

Mod Pathol. 2008 Aug;21(8):943-9. doi: 10.1038/modpathol.2008.84. Epub 2008 May 23.

6.

MDM2 and CDK4 immunostainings are useful adjuncts in diagnosing well-differentiated and dedifferentiated liposarcoma subtypes: a comparative analysis of 559 soft tissue neoplasms with genetic data.

Binh MB, Sastre-Garau X, Guillou L, de Pinieux G, Terrier P, Lagacé R, Aurias A, Hostein I, Coindre JM.

Am J Surg Pathol. 2005 Oct;29(10):1340-7.

PMID:
16160477
7.

Overlapping features between dedifferentiated liposarcoma and undifferentiated high-grade pleomorphic sarcoma.

Chung L, Lau SK, Jiang Z, Loera S, Bedel V, Ji J, Weiss LM, Chu PG.

Am J Surg Pathol. 2009 Nov;33(11):1594-600. doi: 10.1097/PAS.0b013e3181accb01.

PMID:
19574885
8.
9.

Real-time polymerase chain reaction analysis of MDM2 and CDK4 expression using total RNA from core-needle biopsies is useful for diagnosing adipocytic tumors.

Sasaki T, Ogose A, Kawashima H, Hotta T, Hatano H, Ariizumi T, Umezu H, Ohashi R, Tohyama T, Tanabe N, Endo N.

BMC Cancer. 2014 Jun 26;14:468. doi: 10.1186/1471-2407-14-468.

10.

MDM2 and CDK4 Immunohistochemistry: Should It Be Used in Problematic Differentiated Lipomatous Tumors?: A New Perspective.

Clay MR, Martinez AP, Weiss SW, Edgar MA.

Am J Surg Pathol. 2016 Dec;40(12):1647-1652.

PMID:
27508976
11.

Can MDM2 and CDK4 make the diagnosis of well differentiated/dedifferentiated liposarcoma? An immunohistochemical study on 129 soft tissue tumours.

Aleixo PB, Hartmann AA, Menezes IC, Meurer RT, Oliveira AM.

J Clin Pathol. 2009 Dec;62(12):1127-35. doi: 10.1136/jcp.2009.070201.

PMID:
19946100
12.

Atypical spindle cell lipoma: a clinicopathologic, immunohistochemical, and molecular study emphasizing its relationship to classical spindle cell lipoma.

Creytens D, van Gorp J, Savola S, Ferdinande L, Mentzel T, Libbrecht L.

Virchows Arch. 2014 Jul;465(1):97-108.

PMID:
24659226
14.

Comparison of Chromogenic In Situ Hybridization and Fluorescence In Situ Hybridization for the Evaluation of MDM2 Amplification in Adipocytic Tumors.

Mardekian SK, Solomides CC, Gong JZ, Peiper SC, Wang ZX, Bajaj R.

J Clin Lab Anal. 2015 Nov;29(6):462-8. doi: 10.1002/jcla.21794. Epub 2014 Aug 17.

PMID:
25132285
15.

Carboxypeptidase M: a biomarker for the discrimination of well-differentiated liposarcoma from lipoma.

Erickson-Johnson MR, Seys AR, Roth CW, King AA, Hulshizer RL, Wang X, Asmann YW, Lloyd RV, Jacob EK, Oliveira AM.

Mod Pathol. 2009 Dec;22(12):1541-7. doi: 10.1038/modpathol.2009.149. Epub 2009 Oct 9.

16.

Utility of fluorescence in situ hybridization to detect MDM2 amplification in liposarcomas and their morphological mimics.

Kimura H, Dobashi Y, Nojima T, Nakamura H, Yamamoto N, Tsuchiya H, Ikeda H, Sawada-Kitamura S, Oyama T, Ooi A.

Int J Clin Exp Pathol. 2013 Jun 15;6(7):1306-16. Print 2013.

17.

MDM2 and CDK4 immunohistochemistry is a valuable tool in the differential diagnosis of low-grade osteosarcomas and other primary fibro-osseous lesions of the bone.

Dujardin F, Binh MB, Bouvier C, Gomez-Brouchet A, Larousserie F, Muret Ad, Louis-Brennetot C, Aurias A, Coindre JM, Guillou L, Pedeutour F, Duval H, Collin C, de Pinieux G.

Mod Pathol. 2011 May;24(5):624-37. doi: 10.1038/modpathol.2010.229. Epub 2011 Feb 18.

18.

Clinical and biological significance of CDK4 amplification in well-differentiated and dedifferentiated liposarcomas.

Italiano A, Bianchini L, Gjernes E, Keslair F, Ranchere-Vince D, Dumollard JM, Haudebourg J, Leroux A, Mainguené C, Terrier P, Chibon F, Coindre JM, Pedeutour F.

Clin Cancer Res. 2009 Sep 15;15(18):5696-703. doi: 10.1158/1078-0432.CCR-08-3185. Epub 2009 Sep 8.

19.

Prognostic value of HMGA2, CDK4, and JUN amplification in well-differentiated and dedifferentiated liposarcomas.

Saâda-Bouzid E, Burel-Vandenbos F, Ranchère-Vince D, Birtwisle-Peyrottes I, Chetaille B, Bouvier C, Château MC, Peoc'h M, Battistella M, Bazin A, Gal J, Michiels JF, Coindre JM, Pedeutour F, Bianchini L.

Mod Pathol. 2015 Nov;28(11):1404-14. doi: 10.1038/modpathol.2015.96. Epub 2015 Sep 4.

20.

Similarity in genetic alterations between paired well-differentiated and dedifferentiated components of dedifferentiated liposarcoma.

Horvai AE, DeVries S, Roy R, O'Donnell RJ, Waldman F.

Mod Pathol. 2009 Nov;22(11):1477-88. doi: 10.1038/modpathol.2009.119. Epub 2009 Sep 4.

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