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Items: 1 to 20 of 83

1.

Doxorubicin generates a proapoptotic phenotype by phosphorylation of elongation factor 2.

White SJ, Kasman LM, Kelly MM, Lu P, Spruill L, McDermott PJ, Voelkel-Johnson C.

Free Radic Biol Med. 2007 Nov 1;43(9):1313-21. Epub 2007 Jul 3.

2.

Targeting the short form of cFLIP by RNA interference is sufficient to enhance TRAIL sensitivity in PC3 prostate carcinoma cells.

White SJ, Lu P, Keller GM, Voelkel-Johnson C.

Cancer Biol Ther. 2006 Dec;5(12):1618-23. Epub 2006 Dec 5.

PMID:
17106251
3.
4.

TNF Apoptosis Protection Fraction (TAPF) prevents apoptosis induced by TNF, but not by Fas or TRAIL, via NF-κB-induced increase in cFLIP.

Seol JY, Mihich E, Berleth ES.

Cytokine. 2015 Oct;75(2):321-9. doi: 10.1016/j.cyto.2015.05.027. Epub 2015 Jul 18.

PMID:
26198031
5.

Histone deacetylase inhibitors sensitize glioblastoma cells to TRAIL-induced apoptosis by c-myc-mediated downregulation of cFLIP.

Bangert A, Cristofanon S, Eckhardt I, Abhari BA, Kolodziej S, Häcker S, Vellanki SH, Lausen J, Debatin KM, Fulda S.

Oncogene. 2012 Nov 1;31(44):4677-88. doi: 10.1038/onc.2011.614. Epub 2012 Jan 23.

PMID:
22266862
6.

Synergistic proapoptotic activity of recombinant TRAIL plus the Akt inhibitor Perifosine in acute myelogenous leukemia cells.

Tazzari PL, Tabellini G, Ricci F, Papa V, Bortul R, Chiarini F, Evangelisti C, Martinelli G, Bontadini A, Cocco L, McCubrey JA, Martelli AM.

Cancer Res. 2008 Nov 15;68(22):9394-403. doi: 10.1158/0008-5472.CAN-08-2815.

7.

Subtoxic concentration of doxorubicin enhances TRAIL-induced apoptosis in human prostate cancer cell line LNCaP.

Kang J, Bu J, Hao Y, Chen F.

Prostate Cancer Prostatic Dis. 2005;8(3):274-9.

PMID:
15897917
9.
10.

Suppression of cFLIP by lupeol, a dietary triterpene, is sufficient to overcome resistance to TRAIL-mediated apoptosis in chemoresistant human pancreatic cancer cells.

Murtaza I, Saleem M, Adhami VM, Hafeez BB, Mukhtar H.

Cancer Res. 2009 Feb 1;69(3):1156-65. doi: 10.1158/0008-5472.CAN-08-2917. Epub 2009 Jan 27.

12.

Effect of the XIAP inhibitor Embelin on TRAIL-induced apoptosis of pancreatic cancer cells.

Mori T, Doi R, Kida A, Nagai K, Kami K, Ito D, Toyoda E, Kawaguchi Y, Uemoto S.

J Surg Res. 2007 Oct;142(2):281-6. Epub 2007 Jul 19.

PMID:
17640673
13.

Inhibition of ataxia telangiectasia mutated kinase activity enhances TRAIL-mediated apoptosis in human melanoma cells.

Ivanov VN, Zhou H, Partridge MA, Hei TK.

Cancer Res. 2009 Apr 15;69(8):3510-9. doi: 10.1158/0008-5472.CAN-08-3883. Epub 2009 Apr 7.

14.

Chetomin induces degradation of XIAP and enhances TRAIL sensitivity in urogenital cancer cells.

Yano K, Horinaka M, Yoshida T, Yasuda T, Taniguchi H, Goda AE, Wakada M, Yoshikawa S, Nakamura T, Kawauchi A, Miki T, Sakai T.

Int J Oncol. 2011 Feb;38(2):365-74. doi: 10.3892/ijo.2010.874. Epub 2010 Dec 15.

PMID:
21165560
15.

Cathepsin E enhances anticancer activity of doxorubicin on human prostate cancer cells showing resistance to TRAIL-mediated apoptosis.

Yasukochi A, Kawakubo T, Nakamura S, Yamamoto K.

Biol Chem. 2010 Aug;391(8):947-58. doi: 10.1515/BC.2010.087.

PMID:
20482316
16.

Kurarinone promotes TRAIL-induced apoptosis by inhibiting NF-κB-dependent cFLIP expression in HeLa cells.

Seo OW, Kim JH, Lee KS, Lee KS, Kim JH, Won MH, Ha KS, Kwon YG, Kim YM.

Exp Mol Med. 2012 Nov 30;44(11):653-64. doi: 10.3858/emm.2012.44.11.074.

18.

Cellular FLICE/caspase-8-inhibitory protein as a principal regulator of cell death and survival in human hepatocellular carcinoma.

Okano H, Shiraki K, Inoue H, Kawakita T, Yamanaka T, Deguchi M, Sugimoto K, Sakai T, Ohmori S, Fujikawa K, Murata K, Nakano T.

Lab Invest. 2003 Jul;83(7):1033-43.

PMID:
12861043
19.

Oxidative stress sensitizes bladder cancer cells to TRAIL mediated apoptosis by down-regulating anti-apoptotic proteins.

White-Gilbertson SJ, Kasman L, McKillop J, Tirodkar T, Lu P, Voelkel-Johnson C.

J Urol. 2009 Sep;182(3):1178-85. doi: 10.1016/j.juro.2009.05.005. Epub 2009 Jul 21.

20.

c-Fos as a proapoptotic agent in TRAIL-induced apoptosis in prostate cancer cells.

Zhang X, Zhang L, Yang H, Huang X, Otu H, Libermann TA, DeWolf WC, Khosravi-Far R, Olumi AF.

Cancer Res. 2007 Oct 1;67(19):9425-34.

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