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Items: 1 to 20 of 206

1.

Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids.

Stein A, Radhakrishnan A, Riedel D, Fasshauer D, Jahn R.

Nat Struct Mol Biol. 2007 Oct;14(10):904-11. Epub 2007 Sep 23.

PMID:
17891149
2.

Ca(2+)-synaptotagmin directly regulates t-SNARE function during reconstituted membrane fusion.

Bhalla A, Chicka MC, Tucker WC, Chapman ER.

Nat Struct Mol Biol. 2006 Apr;13(4):323-30. Epub 2006 Mar 26.

PMID:
16565726
3.

Hemifusion arrest by complexin is relieved by Ca2+-synaptotagmin I.

Schaub JR, Lu X, Doneske B, Shin YK, McNew JA.

Nat Struct Mol Biol. 2006 Aug;13(8):748-50. Epub 2006 Jul 16.

PMID:
16845390
4.

Kinetics of synaptotagmin responses to Ca2+ and assembly with the core SNARE complex onto membranes.

Davis AF, Bai J, Fasshauer D, Wolowick MJ, Lewis JL, Chapman ER.

Neuron. 1999 Oct;24(2):363-76. Erratum in: Neuron 1999 Dec;24(4):1049.

5.

Synaptotagmin I and Ca(2+) promote half fusion more than full fusion in SNARE-mediated bilayer fusion.

Lu X, Xu Y, Zhang F, Shin YK.

FEBS Lett. 2006 Apr 17;580(9):2238-46. Epub 2006 Mar 20.

6.

Unraveling the mechanisms of synaptotagmin and SNARE function in neurotransmitter release.

Rizo J, Chen X, Araç D.

Trends Cell Biol. 2006 Jul;16(7):339-50. Epub 2006 May 12. Review. Erratum in: Trends Cell Biol. 2006 Nov;16(11):549-50.

PMID:
16698267
8.

SNAREpin assembly by Munc18-1 requires previous vesicle docking by synaptotagmin 1.

Parisotto D, Malsam J, Scheutzow A, Krause JM, Söllner TH.

J Biol Chem. 2012 Sep 7;287(37):31041-9. doi: 10.1074/jbc.M112.386805. Epub 2012 Jul 18.

9.

A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis.

Tang J, Maximov A, Shin OH, Dai H, Rizo J, Südhof TC.

Cell. 2006 Sep 22;126(6):1175-87.

10.

Reconstitution of Ca2+-regulated membrane fusion by synaptotagmin and SNAREs.

Tucker WC, Weber T, Chapman ER.

Science. 2004 Apr 16;304(5669):435-8. Epub 2004 Mar 25.

11.

Calcium-dependent translocation of synaptotagmin to the plasma membrane in the dendrites of developing neurones.

Schwab Y, Mouton J, Chasserot-Golaz S, Marty I, Maulet Y, Jover E.

Brain Res Mol Brain Res. 2001 Nov 30;96(1-2):1-13.

PMID:
11731003
12.

C-terminal ECFP fusion impairs synaptotagmin 1 function: crowding out synaptotagmin 1.

Han W, Rhee JS, Maximov A, Lin W, Hammer RE, Rosenmund C, Südhof TC.

J Biol Chem. 2005 Feb 11;280(6):5089-100. Epub 2004 Nov 23.

13.

Controlling synaptotagmin activity by electrostatic screening.

Park Y, Hernandez JM, van den Bogaart G, Ahmed S, Holt M, Riedel D, Jahn R.

Nat Struct Mol Biol. 2012 Oct;19(10):991-7. doi: 10.1038/nsmb.2375. Epub 2012 Sep 2.

14.

Synaptotagmin-1 may be a distance regulator acting upstream of SNARE nucleation.

van den Bogaart G, Thutupalli S, Risselada JH, Meyenberg K, Holt M, Riedel D, Diederichsen U, Herminghaus S, Grubmüller H, Jahn R.

Nat Struct Mol Biol. 2011 Jun 5;18(7):805-12. doi: 10.1038/nsmb.2061.

15.

Different effects on fast exocytosis induced by synaptotagmin 1 and 2 isoforms and abundance but not by phosphorylation.

Nagy G, Kim JH, Pang ZP, Matti U, Rettig J, Südhof TC, Sørensen JB.

J Neurosci. 2006 Jan 11;26(2):632-43.

16.

A clamping mechanism involved in SNARE-dependent exocytosis.

Giraudo CG, Eng WS, Melia TJ, Rothman JE.

Science. 2006 Aug 4;313(5787):676-80. Epub 2006 Jun 22.

17.

Tomosyn inhibits synaptotagmin-1-mediated step of Ca2+-dependent neurotransmitter release through its N-terminal WD40 repeats.

Yamamoto Y, Mochida S, Miyazaki N, Kawai K, Fujikura K, Kurooka T, Iwasaki K, Sakisaka T.

J Biol Chem. 2010 Dec 24;285(52):40943-55. doi: 10.1074/jbc.M110.156893. Epub 2010 Oct 26.

18.

Cis- and trans-membrane interactions of synaptotagmin-1.

Vennekate W, Schröder S, Lin CC, van den Bogaart G, Grunwald M, Jahn R, Walla PJ.

Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):11037-42. doi: 10.1073/pnas.1116326109. Epub 2012 Jun 18.

19.

Gβγ directly modulates vesicle fusion by competing with synaptotagmin for binding to neuronal SNARE proteins embedded in membranes.

Zurawski Z, Page B, Chicka MC, Brindley RL, Wells CA, Preininger AM, Hyde K, Gilbert JA, Cruz-Rodriguez O, Currie KPM, Chapman ER, Alford S, Hamm HE.

J Biol Chem. 2017 Jul 21;292(29):12165-12177. doi: 10.1074/jbc.M116.773523. Epub 2017 May 17.

PMID:
28515322
20.

Mechanism and function of synaptotagmin-mediated membrane apposition.

Hui E, Gaffaney JD, Wang Z, Johnson CP, Evans CS, Chapman ER.

Nat Struct Mol Biol. 2011 Jun 5;18(7):813-21. doi: 10.1038/nsmb.2075.

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