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Items: 1 to 20 of 406

1.

Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia.

Pletnikov MV, Ayhan Y, Nikolskaia O, Xu Y, Ovanesov MV, Huang H, Mori S, Moran TH, Ross CA.

Mol Psychiatry. 2008 Feb;13(2):173-86, 115. Epub 2007 Sep 11.

PMID:
17848917
2.

Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1.

Shen S, Lang B, Nakamoto C, Zhang F, Pu J, Kuan SL, Chatzi C, He S, Mackie I, Brandon NJ, Marquis KL, Day M, Hurko O, McCaig CD, Riedel G, St Clair D.

J Neurosci. 2008 Oct 22;28(43):10893-904. doi: 10.1523/JNEUROSCI.3299-08.2008.

3.

PC12 cell model of inducible expression of mutant DISC1: new evidence for a dominant-negative mechanism of abnormal neuronal differentiation.

Pletnikov MV, Xu Y, Ovanesov MV, Kamiya A, Sawa A, Ross CA.

Neurosci Res. 2007 Jul;58(3):234-44. Epub 2007 Mar 16.

PMID:
17418909
4.

Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders.

Ayhan Y, Abazyan B, Nomura J, Kim R, Ladenheim B, Krasnova IN, Sawa A, Margolis RL, Cadet JL, Mori S, Vogel MW, Ross CA, Pletnikov MV.

Mol Psychiatry. 2011 Mar;16(3):293-306. doi: 10.1038/mp.2009.144. Epub 2010 Jan 5.

5.

Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders.

Brandon NJ, Handford EJ, Schurov I, Rain JC, Pelling M, Duran-Jimeniz B, Camargo LM, Oliver KR, Beher D, Shearman MS, Whiting PJ.

Mol Cell Neurosci. 2004 Jan;25(1):42-55.

PMID:
14962739
6.

A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development.

Kamiya A, Kubo K, Tomoda T, Takaki M, Youn R, Ozeki Y, Sawamura N, Park U, Kudo C, Okawa M, Ross CA, Hatten ME, Nakajima K, Sawa A.

Nat Cell Biol. 2005 Dec;7(12):1167-78. Epub 2005 Nov 20. Erratum in: Nat Cell Biol. 2006 Jan;8(1):100.

PMID:
16299498
7.

Expression of disrupted in schizophrenia 1 (DISC1) protein in the adult and developing mouse brain indicates its role in neurodevelopment.

Schurov IL, Handford EJ, Brandon NJ, Whiting PJ.

Mol Psychiatry. 2004 Dec;9(12):1100-10.

PMID:
15381924
8.

Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth.

Miyoshi K, Honda A, Baba K, Taniguchi M, Oono K, Fujita T, Kuroda S, Katayama T, Tohyama M.

Mol Psychiatry. 2003 Jul;8(7):685-94.

PMID:
12874605
9.

DISC1 (Disrupted in Schizophrenia-1) is expressed in limbic regions of the primate brain.

Austin CP, Ma L, Ky B, Morris JA, Shughrue PJ.

Neuroreport. 2003 May 23;14(7):951-4.

PMID:
12802181
10.

A review of Disrupted-In-Schizophrenia-1 (DISC1): neurodevelopment, cognition, and mental conditions.

Ishizuka K, Paek M, Kamiya A, Sawa A.

Biol Psychiatry. 2006 Jun 15;59(12):1189-97. Review.

PMID:
16797264
11.

Additive effect of NRG1 and DISC1 genes on lateral ventricle enlargement in first episode schizophrenia.

Mata I, Perez-Iglesias R, Roiz-SantiaƱez R, Tordesillas-Gutierrez D, Gonzalez-Mandly A, Berja A, Vazquez-Barquero JL, Crespo-Facorro B.

Neuroimage. 2010 Nov 15;53(3):1016-22. doi: 10.1016/j.neuroimage.2009.11.010. Epub 2009 Nov 12.

PMID:
19913623
12.
13.

Molecular mechanism of schizophrenia with reference to disrupted-in-schizophrenia 1 (DISC1).

Matsuzaki S, Tohyama M.

Neurochem Int. 2007 Jul-Sep;51(2-4):165-72. Epub 2007 Jun 27. Review.

PMID:
17664024
14.

Effects of antipsychotics on the behavioral deficits in human dominant-negative DISC1 transgenic mice with neonatal polyI:C treatment.

Nagai T, Kitahara Y, Ibi D, Nabeshima T, Sawa A, Yamada K.

Behav Brain Res. 2011 Nov 20;225(1):305-10. doi: 10.1016/j.bbr.2011.07.049. Epub 2011 Aug 3.

PMID:
21835207
15.

A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder.

Sachs NA, Sawa A, Holmes SE, Ross CA, DeLisi LE, Margolis RL.

Mol Psychiatry. 2005 Aug;10(8):758-64.

PMID:
15940305
16.

Gene models of schizophrenia: DISC1 mouse models.

Jaaro-Peled H.

Prog Brain Res. 2009;179:75-86. doi: 10.1016/S0079-6123(09)17909-8. Epub 2009 Nov 20. Review.

PMID:
20302820
17.

A novel DISC1-interacting partner DISC1-Binding Zinc-finger protein: implication in the modulation of DISC1-dependent neurite outgrowth.

Hattori T, Baba K, Matsuzaki S, Honda A, Miyoshi K, Inoue K, Taniguchi M, Hashimoto H, Shintani N, Baba A, Shimizu S, Yukioka F, Kumamoto N, Yamaguchi A, Tohyama M, Katayama T.

Mol Psychiatry. 2007 Apr;12(4):398-407. Epub 2007 Jan 23.

PMID:
17389905
18.

Enhanced dopamine function in DISC1-L100P mutant mice: implications for schizophrenia.

Lipina TV, Niwa M, Jaaro-Peled H, Fletcher PJ, Seeman P, Sawa A, Roder JC.

Genes Brain Behav. 2010 Oct;9(7):777-89. doi: 10.1111/j.1601-183X.2010.00615.x. Epub 2010 Aug 12.

19.

Insolubility of disrupted-in-schizophrenia 1 disrupts oligomer-dependent interactions with nuclear distribution element 1 and is associated with sporadic mental disease.

Leliveld SR, Bader V, Hendriks P, Prikulis I, Sajnani G, Requena JR, Korth C.

J Neurosci. 2008 Apr 9;28(15):3839-45. doi: 10.1523/JNEUROSCI.5389-07.2008.

20.

Frontal cortical synaptic communication is abnormal in Disc1 genetic mouse models of schizophrenia.

Holley SM, Wang EA, Cepeda C, Jentsch JD, Ross CA, Pletnikov MV, Levine MS.

Schizophr Res. 2013 May;146(1-3):264-72. doi: 10.1016/j.schres.2013.02.007. Epub 2013 Mar 6.

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