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Items: 1 to 20 of 99

1.

Transcriptional vulnerability of brain regions in Alzheimer's disease and dementia.

Haroutunian V, Katsel P, Schmeidler J.

Neurobiol Aging. 2009 Apr;30(4):561-73. Epub 2007 Sep 12.

2.

Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer's disease.

Wang M, Roussos P, McKenzie A, Zhou X, Kajiwara Y, Brennand KJ, De Luca GC, Crary JF, Casaccia P, Buxbaum JD, Ehrlich M, Gandy S, Goate A, Katsel P, Schadt E, Haroutunian V, Zhang B.

Genome Med. 2016 Nov 1;8(1):104.

3.

Cortical neuritic plaques and hippocampal neurofibrillary tangles are related to dementia severity in elderly schizophrenia patients.

Rapp MA, Schnaider-Beeri M, Purohit DP, Reichenberg A, McGurk SR, Haroutunian V, Harvey PD.

Schizophr Res. 2010 Jan;116(1):90-6. doi: 10.1016/j.schres.2009.10.013.

4.

Increased expression of cholesterol transporter ABCA1 is highly correlated with severity of dementia in AD hippocampus.

Akram A, Schmeidler J, Katsel P, Hof PR, Haroutunian V.

Brain Res. 2010 Mar 8;1318:167-77. doi: 10.1016/j.brainres.2010.01.006. Epub 2010 Jan 14.

5.

Neurofibrillary tangle-predominant dementia: comparison with classical Alzheimer disease.

Jellinger KA, Attems J.

Acta Neuropathol. 2007 Feb;113(2):107-17. Epub 2006 Nov 7.

PMID:
17089134
6.

Apolipoprotein E genotype in senile dementia with tangles differs from Alzheimer's disease.

Tolnay M, Villoz N, Probst A, Miserez AR.

Neuropathol Appl Neurobiol. 2003 Feb;29(1):80-4. No abstract available.

PMID:
12581343
7.

Association of ApoE and LRP mRNA levels with dementia and AD neuropathology.

Akram A, Schmeidler J, Katsel P, Hof PR, Haroutunian V.

Neurobiol Aging. 2012 Mar;33(3):628.e1-628.e14. doi: 10.1016/j.neurobiolaging.2011.04.010. Epub 2011 Jun 15.

8.

Neuropathologically defined subtypes of Alzheimer's disease differ significantly from neurofibrillary tangle-predominant dementia.

Janocko NJ, Brodersen KA, Soto-Ortolaza AI, Ross OA, Liesinger AM, Duara R, Graff-Radford NR, Dickson DW, Murray ME.

Acta Neuropathol. 2012 Nov;124(5):681-92. doi: 10.1007/s00401-012-1044-y. Epub 2012 Sep 12.

9.

Thinking outside the box: Alzheimer-type neuropathology that does not map directly onto current consensus recommendations.

Nelson PT, Kukull WA, Frosch MP.

J Neuropathol Exp Neurol. 2010 May;69(5):449-54. doi: 10.1097/NEN.0b013e3181d8db07.

10.

Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set.

Liang WS, Dunckley T, Beach TG, Grover A, Mastroeni D, Ramsey K, Caselli RJ, Kukull WA, McKeel D, Morris JC, Hulette CM, Schmechel D, Reiman EM, Rogers J, Stephan DA.

Physiol Genomics. 2008 Apr 22;33(2):240-56. doi: 10.1152/physiolgenomics.00242.2007. Epub 2008 Feb 12.

11.

Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype.

Berg L, McKeel DW Jr, Miller JP, Storandt M, Rubin EH, Morris JC, Baty J, Coats M, Norton J, Goate AM, Price JL, Gearing M, Mirra SS, Saunders AM.

Arch Neurol. 1998 Mar;55(3):326-35.

PMID:
9520006
12.

Transcriptional alterations related to neuropathology and clinical manifestation of Alzheimer's disease.

Silva AR, Grinberg LT, Farfel JM, Diniz BS, Lima LA, Silva PJ, Ferretti RE, Rocha RM, Filho WJ, Carraro DM, Brentani H.

PLoS One. 2012;7(11):e48751. doi: 10.1371/journal.pone.0048751. Epub 2012 Nov 7.

13.

Genes associated with the progression of neurofibrillary tangles in Alzheimer's disease.

Miyashita A, Hatsuta H, Kikuchi M, Nakaya A, Saito Y, Tsukie T, Hara N, Ogishima S, Kitamura N, Akazawa K, Kakita A, Takahashi H, Murayama S, Ihara Y, Ikeuchi T, Kuwano R; Japanese Alzheimer's Disease Neuroimaging Initiative.

Transl Psychiatry. 2014 Jun 10;4:e396. doi: 10.1038/tp.2014.35.

14.

Neocortical neurofibrillary tangles correlate with dementia severity in Alzheimer's disease.

Bierer LM, Hof PR, Purohit DP, Carlin L, Schmeidler J, Davis KL, Perl DP.

Arch Neurol. 1995 Jan;52(1):81-8.

PMID:
7826280
15.

"End-stage" neurofibrillary tangle pathology in preclinical Alzheimer's disease: fact or fiction?

Abner EL, Kryscio RJ, Schmitt FA, Santacruz KS, Jicha GA, Lin Y, Neltner JM, Smith CD, Van Eldik LJ, Nelson PT.

J Alzheimers Dis. 2011;25(3):445-53. doi: 10.3233/JAD-2011-101980.

16.

Concerted changes in transcripts in the prefrontal cortex precede neuropathology in Alzheimer's disease.

Bossers K, Wirz KT, Meerhoff GF, Essing AH, van Dongen JW, Houba P, Kruse CG, Verhaagen J, Swaab DF.

Brain. 2010 Dec;133(Pt 12):3699-723. doi: 10.1093/brain/awq258. Epub 2010 Oct 1.

PMID:
20889584
17.

Neuropathologically defined subtypes of Alzheimer's disease with distinct clinical characteristics: a retrospective study.

Murray ME, Graff-Radford NR, Ross OA, Petersen RC, Duara R, Dickson DW.

Lancet Neurol. 2011 Sep;10(9):785-96. doi: 10.1016/S1474-4422(11)70156-9. Epub 2011 Jul 27.

18.

Clinical validity of Braak neuropathological staging in the oldest-old.

Gold G, Bouras C, Kövari E, Canuto A, Glaría BG, Malky A, Hof PR, Michel JP, Giannakopoulos P.

Acta Neuropathol. 2000 May;99(5):579-82; discussion 583-4.

PMID:
10805104
19.

Neuronal gene expression in non-demented individuals with intermediate Alzheimer's Disease neuropathology.

Liang WS, Dunckley T, Beach TG, Grover A, Mastroeni D, Ramsey K, Caselli RJ, Kukull WA, McKeel D, Morris JC, Hulette CM, Schmechel D, Reiman EM, Rogers J, Stephan DA.

Neurobiol Aging. 2010 Apr;31(4):549-66. doi: 10.1016/j.neurobiolaging.2008.05.013. Epub 2008 Jun 24.

20.

Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models.

Martiskainen H, Viswanathan J, Nykänen NP, Kurki M, Helisalmi S, Natunen T, Sarajärvi T, Kurkinen KM, Pursiheimo JP, Rauramaa T, Alafuzoff I, Jääskeläinen JE, Leinonen V, Soininen H, Haapasalo A, Huttunen HJ, Hiltunen M.

Neurobiol Aging. 2015 Feb;36(2):1221.e15-28. doi: 10.1016/j.neurobiolaging.2014.09.003. Epub 2014 Sep 6.

PMID:
25281018

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