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Items: 1 to 20 of 236

1.

Evaluation of commercial kava extracts and kavalactone standards for mutagenicity and toxicity using the mammalian cell gene mutation assay in L5178Y mouse lymphoma cells.

Whittaker P, Clarke JJ, San RH, Betz JM, Seifried HE, de Jager LS, Dunkel VC.

Food Chem Toxicol. 2008 Jan;46(1):168-74. Epub 2007 Jul 31.

PMID:
17822821
2.

In vitro toxicity of kava alkaloid, pipermethystine, in HepG2 cells compared to kavalactones.

Nerurkar PV, Dragull K, Tang CS.

Toxicol Sci. 2004 May;79(1):106-11. Epub 2004 Jan 21.

PMID:
14737001
3.

Methysticin and 7,8-dihydromethysticin are two major kavalactones in kava extract to induce CYP1A1.

Li Y, Mei H, Wu Q, Zhang S, Fang JL, Shi L, Guo L.

Toxicol Sci. 2011 Dec;124(2):388-99. doi: 10.1093/toxsci/kfr235. Epub 2011 Sep 9.

4.

Pharmacokinetics and disposition of the kavalactone kawain: interaction with kava extract and kavalactones in vivo and in vitro.

Mathews JM, Etheridge AS, Valentine JL, Black SR, Coleman DP, Patel P, So J, Burka LT.

Drug Metab Dispos. 2005 Oct;33(10):1555-63. Epub 2005 Jul 20.

5.

Extracts and kavalactones of Piper methysticum G. Forst (kava-kava) inhibit P-glycoprotein in vitro.

Weiss J, Sauer A, Frank A, Unger M.

Drug Metab Dispos. 2005 Nov;33(11):1580-3. Epub 2005 Jul 28.

6.

Determination of kavalactones in dried kava (Piper methysticum) powder using near-infrared reflectance spectroscopy and partial least-squares regression.

Gautz LD, Kaufusi P, Jackson MC, Bittenbender HC, Tang CS.

J Agric Food Chem. 2006 Aug 23;54(17):6147-52.

PMID:
16910700
7.

Melanogenesis stimulation in murine B16 melanoma cells by Kava (Piper methysticum) rhizome extract and kavalactones.

Matsuda H, Hirata N, Kawaguchi Y, Naruto S, Takata T, Oyama M, Iinuma M, Kubo M.

Biol Pharm Bull. 2006 Apr;29(4):834-7.

8.

Desmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with marked activity on the induction of CYP3A23.

Ma Y, Sachdeva K, Liu J, Ford M, Yang D, Khan IA, Chichester CO, Yan B.

Drug Metab Dispos. 2004 Nov;32(11):1317-24. Epub 2004 Jul 28.

9.

Composition and biological activity of traditional and commercial kava extracts.

Côté CS, Kor C, Cohen J, Auclair K.

Biochem Biophys Res Commun. 2004 Sep 10;322(1):147-52.

PMID:
15313185
11.

LC-UV and LC-MS analysis of food and drink products containing kava.

de Jager LS, Perfetti GA, Diachenko GW.

Food Addit Contam. 2004 Oct;21(10):921-34.

PMID:
15712517
12.

Proposal for a kava quality standardization code.

Teschke R, Lebot V.

Food Chem Toxicol. 2011 Oct;49(10):2503-16. doi: 10.1016/j.fct.2011.06.075. Epub 2011 Jul 3. Review.

PMID:
21756963
13.

Analysis of kavalactones from Piper methysticum (kava-kava).

Bilia AR, Scalise L, Bergonzi MC, Vincieri FF.

J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Dec 5;812(1-2):203-14. Review.

PMID:
15556499
14.

Kavalactone content and chemotype of kava beverages prepared from roots and rhizomes of Isa and Mahakea varieties and extraction efficiency of kavalactones using different solvents.

Wang J, Qu W, Bittenbender HC, Li QX.

J Food Sci Technol. 2015 Feb;52(2):1164-9. doi: 10.1007/s13197-013-1047-2. Epub 2013 Jun 25.

15.

Determination of kava lactones in food supplements by liquid chromatography-atmospheric pressure chemical ionisation tandem mass spectrometry.

Bobeldijk I, Boonzaaijer G, Spies-Faber EJ, Vaes WH.

J Chromatogr A. 2005 Mar 4;1067(1-2):107-14.

PMID:
15844515
16.

Densitometric analysis of kawain in kava-kava root extracts.

Janeczko Z, Krzek J, Pilewski N, Walusiak D.

Acta Pol Pharm. 2001 Nov-Dec;58(6):463-8.

17.

Anxiolytic effects of kava extract and kavalactones in the chick social separation-stress paradigm.

Smith KK, Dharmaratne HR, Feltenstein MW, Broom SL, Roach JT, Nanayakkara NP, Khan IA, Sufka KJ.

Psychopharmacology (Berl). 2001 Apr;155(1):86-90.

PMID:
11374340
18.

Inhibition of human cytochrome P450 activities by kava extract and kavalactones.

Mathews JM, Etheridge AS, Black SR.

Drug Metab Dispos. 2002 Nov;30(11):1153-7.

19.

High dose of commercial products of kava (Piper methysticum) markedly enhanced hepatic cytochrome P450 1A1 mRNA expression with liver enlargement in rats.

Yamazaki Y, Hashida H, Arita A, Hamaguchi K, Shimura F.

Food Chem Toxicol. 2008 Dec;46(12):3732-8. doi: 10.1016/j.fct.2008.09.052. Epub 2008 Sep 30.

PMID:
18930106
20.

Kava-kava and anxiety: growing knowledge about the efficacy and safety.

Bilia AR, Gallon S, Vincieri FF.

Life Sci. 2002 Apr 19;70(22):2581-97. Review.

PMID:
12269386

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