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Items: 1 to 20 of 114

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2.

Prefrontal dysfunction in schizophrenia involves mixed-lineage leukemia 1-regulated histone methylation at GABAergic gene promoters.

Huang HS, Matevossian A, Whittle C, Kim SY, Schumacher A, Baker SP, Akbarian S.

J Neurosci. 2007 Oct 17;27(42):11254-62.

3.

Conserved chromosome 2q31 conformations are associated with transcriptional regulation of GAD1 GABA synthesis enzyme and altered in prefrontal cortex of subjects with schizophrenia.

Bharadwaj R, Jiang Y, Mao W, Jakovcevski M, Dincer A, Krueger W, Garbett K, Whittle C, Tushir JS, Liu J, Sequeira A, Vawter MP, Gardner PD, Casaccia P, Rasmussen T, Bunney WE Jr, Mirnics K, Futai K, Akbarian S.

J Neurosci. 2013 Jul 17;33(29):11839-51. doi: 10.1523/JNEUROSCI.1252-13.2013.

4.

Reelin and glutamic acid decarboxylase67 promoter remodeling in an epigenetic methionine-induced mouse model of schizophrenia.

Dong E, Agis-Balboa RC, Simonini MV, Grayson DR, Costa E, Guidotti A.

Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12578-83. Epub 2005 Aug 19.

5.

Maternal care and DNA methylation of a glutamic acid decarboxylase 1 promoter in rat hippocampus.

Zhang TY, Hellstrom IC, Bagot RC, Wen X, Diorio J, Meaney MJ.

J Neurosci. 2010 Sep 29;30(39):13130-7. doi: 10.1523/JNEUROSCI.1039-10.2010.

6.

Transcriptional regulation of GAD1 GABA synthesis gene in the prefrontal cortex of subjects with schizophrenia.

Mitchell AC, Jiang Y, Peter C, Akbarian S.

Schizophr Res. 2015 Sep;167(1-3):28-34. doi: 10.1016/j.schres.2014.10.020. Epub 2014 Oct 31. Review.

7.

Analysis of the GAD1 promoter: trans-acting factors and DNA methylation converge on the 5' untranslated region.

Chen Y, Dong E, Grayson DR.

Neuropharmacology. 2011 Jun;60(7-8):1075-87. doi: 10.1016/j.neuropharm.2010.09.017. Epub 2010 Sep 28.

PMID:
20869372
8.

Circuit- and Diagnosis-Specific DNA Methylation Changes at γ-Aminobutyric Acid-Related Genes in Postmortem Human Hippocampus in Schizophrenia and Bipolar Disorder.

Ruzicka WB, Subburaju S, Benes FM.

JAMA Psychiatry. 2015 Jun;72(6):541-51. doi: 10.1001/jamapsychiatry.2015.49.

PMID:
25738424
9.

Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia.

Hashimoto T, Volk DW, Eggan SM, Mirnics K, Pierri JN, Sun Z, Sampson AR, Lewis DA.

J Neurosci. 2003 Jul 16;23(15):6315-26.

10.

Epigenetic signature of panic disorder: a role of glutamate decarboxylase 1 (GAD1) DNA hypomethylation?

Domschke K, Tidow N, Schrempf M, Schwarte K, Klauke B, Reif A, Kersting A, Arolt V, Zwanzger P, Deckert J.

Prog Neuropsychopharmacol Biol Psychiatry. 2013 Oct 1;46:189-96. doi: 10.1016/j.pnpbp.2013.07.014. Epub 2013 Jul 29.

PMID:
23906988
11.
12.

Chromatin alterations associated with down-regulated metabolic gene expression in the prefrontal cortex of subjects with schizophrenia.

Akbarian S, Ruehl MG, Bliven E, Luiz LA, Peranelli AC, Baker SP, Roberts RC, Bunney WE Jr, Conley RC, Jones EG, Tamminga CA, Guo Y.

Arch Gen Psychiatry. 2005 Aug;62(8):829-40.

PMID:
16061760
13.

DNA-methyltransferase 1 mRNA is selectively overexpressed in telencephalic GABAergic interneurons of schizophrenia brains.

Veldic M, Caruncho HJ, Liu WS, Davis J, Satta R, Grayson DR, Guidotti A, Costa E.

Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):348-53. Epub 2003 Dec 18.

14.

Molecular determinants of dysregulated GABAergic gene expression in the prefrontal cortex of subjects with schizophrenia.

Mellios N, Huang HS, Baker SP, Galdzicka M, Ginns E, Akbarian S.

Biol Psychiatry. 2009 Jun 15;65(12):1006-14. doi: 10.1016/j.biopsych.2008.11.019. Epub 2009 Jan 1.

PMID:
19121517
15.

Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disorders.

Akbarian S, Huang HS.

Brain Res Rev. 2006 Sep;52(2):293-304. Epub 2006 Jun 8. Review.

PMID:
16759710
16.

GABAergic cortical neuron chromatin as a putative target to treat schizophrenia vulnerability.

Costa E, Grayson DR, Mitchell CP, Tremolizzo L, Veldic M, Guidotti A.

Crit Rev Neurobiol. 2003;15(2):121-42. Review.

PMID:
14977367
17.

Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics.

Akbarian S, Kim JJ, Potkin SG, Hagman JO, Tafazzoli A, Bunney WE Jr, Jones EG.

Arch Gen Psychiatry. 1995 Apr;52(4):258-66.

PMID:
7702443
18.

DNA methyltransferase 1 regulates reelin mRNA expression in mouse primary cortical cultures.

Noh JS, Sharma RP, Veldic M, Salvacion AA, Jia X, Chen Y, Costa E, Guidotti A, Grayson DR.

Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1749-54. Epub 2005 Jan 25.

19.
20.

DNA-methyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients.

Dong E, Ruzicka WB, Grayson DR, Guidotti A.

Schizophr Res. 2015 Sep;167(1-3):35-41. doi: 10.1016/j.schres.2014.10.030. Epub 2014 Dec 2.

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