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Items: 1 to 20 of 102

1.

JAK2 tyrosine kinase phosphorylates PAK1 and regulates PAK1 activity and functions.

Rider L, Shatrova A, Feener EP, Webb L, Diakonova M.

J Biol Chem. 2007 Oct 19;282(42):30985-96. Epub 2007 Aug 28.

2.

Tyrosyl phosphorylated PAK1 regulates breast cancer cell motility in response to prolactin through filamin A.

Hammer A, Rider L, Oladimeji P, Cook L, Li Q, Mattingly RR, Diakonova M.

Mol Endocrinol. 2013 Mar;27(3):455-65. doi: 10.1210/me.2012-1291. Epub 2013 Jan 22.

3.
4.

Phosphorylation of tyrosine 285 of PAK1 facilitates βPIX/GIT1 binding and adhesion turnover.

Hammer A, Oladimeji P, De Las Casas LE, Diakonova M.

FASEB J. 2015 Mar;29(3):943-59. doi: 10.1096/fj.14-259366. Epub 2014 Dec 2.

5.

Adapter protein SH2B1beta binds filamin A to regulate prolactin-dependent cytoskeletal reorganization and cell motility.

Rider L, Diakonova M.

Mol Endocrinol. 2011 Jul;25(7):1231-43. doi: 10.1210/me.2011-0056. Epub 2011 May 12.

6.

PAK1 regulates breast cancer cell invasion through secretion of matrix metalloproteinases in response to prolactin and three-dimensional collagen IV.

Rider L, Oladimeji P, Diakonova M.

Mol Endocrinol. 2013 Jul;27(7):1048-64. doi: 10.1210/me.2012-1322. Epub 2013 Jun 6.

7.

Tyrosyl phosphorylated serine-threonine kinase PAK1 is a novel regulator of prolactin-dependent breast cancer cell motility and invasion.

Hammer A, Diakonova M.

Adv Exp Med Biol. 2015;846:97-137. doi: 10.1007/978-3-319-12114-7_5. Review.

8.

PAK1-Nck regulates cyclin D1 promoter activity in response to prolactin.

Tao J, Oladimeji P, Rider L, Diakonova M.

Mol Endocrinol. 2011 Sep;25(9):1565-78. doi: 10.1210/me.2011-0062. Epub 2011 Jun 30.

9.

Dissecting activation of the PAK1 kinase at protrusions in living cells.

Parrini MC, Camonis J, Matsuda M, de Gunzburg J.

J Biol Chem. 2009 Sep 4;284(36):24133-43. doi: 10.1074/jbc.M109.015271. Epub 2009 Jul 1.

10.

Trihydrophobin 1 Interacts with PAK1 and Regulates ERK/MAPK Activation and Cell Migration.

Cheng C, Kong X, Wang H, Gan H, Hao Y, Zou W, Wu J, Chi Y, Yang J, Hong Y, Chen K, Gu J.

J Biol Chem. 2009 Mar 27;284(13):8786-96. doi: 10.1074/jbc.M806144200. Epub 2009 Jan 9.

11.

Identification of tyrosine 972 as a novel site of Jak2 tyrosine kinase phosphorylation and its role in Jak2 activation.

McDoom I, Ma X, Kirabo A, Lee KY, Ostrov DA, Sayeski PP.

Biochemistry. 2008 Aug 12;47(32):8326-34. doi: 10.1021/bi800867d. Epub 2008 Jul 18.

12.

JAK2 tyrosine kinase phosphorylates and is negatively regulated by centrosomal protein Ninein.

Jay J, Hammer A, Nestor-Kalinoski A, Diakonova M.

Mol Cell Biol. 2015 Jan;35(1):111-31. doi: 10.1128/MCB.01138-14. Epub 2014 Oct 20.

13.

Protein kinase CK2 phosphorylates and activates p21-activated kinase 1.

Shin YJ, Kim YB, Kim JH.

Mol Biol Cell. 2013 Sep;24(18):2990-9. doi: 10.1091/mbc.E13-04-0204. Epub 2013 Jul 24.

14.

PAK1 tyrosine phosphorylation is required to induce epithelial-mesenchymal transition and radioresistance in lung cancer cells.

Kim E, Youn H, Kwon T, Son B, Kang J, Yang HJ, Seong KM, Kim W, Youn B.

Cancer Res. 2014 Oct 1;74(19):5520-31. doi: 10.1158/0008-5472.CAN-14-0735. Epub 2014 Aug 14.

15.

Synapses of amphids defective (SAD-A) kinase promotes glucose-stimulated insulin secretion through activation of p21-activated kinase (PAK1) in pancreatic β-Cells.

Nie J, Sun C, Faruque O, Ye G, Li J, Liang Q, Chang Z, Yang W, Han X, Shi Y.

J Biol Chem. 2012 Jul 27;287(31):26435-44. doi: 10.1074/jbc.M112.378372. Epub 2012 Jun 5.

16.

Activation of p21-activated kinase 1 is required for lysophosphatidic acid-induced focal adhesion kinase phosphorylation and cell motility in human melanoma A2058 cells.

Jung ID, Lee J, Lee KB, Park CG, Kim YK, Seo DW, Park D, Lee HW, Han JW, Lee HY.

Eur J Biochem. 2004 Apr;271(8):1557-65.

17.

Regulation of Akt/PKB activity by P21-activated kinase in cardiomyocytes.

Mao K, Kobayashi S, Jaffer ZM, Huang Y, Volden P, Chernoff J, Liang Q.

J Mol Cell Cardiol. 2008 Feb;44(2):429-34. Epub 2007 Dec 3.

18.

ArgBP2gamma interacts with Akt and p21-activated kinase-1 and promotes cell survival.

Yuan ZQ, Kim D, Kaneko S, Sussman M, Bokoch GM, Kruh GD, Nicosia SV, Testa JR, Cheng JQ.

J Biol Chem. 2005 Jun 3;280(22):21483-90. Epub 2005 Mar 22. Retraction in: J Biol Chem. 2016 Oct 21;291(43):22845.

19.

p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1).

King CC, Gardiner EM, Zenke FT, Bohl BP, Newton AC, Hemmings BA, Bokoch GM.

J Biol Chem. 2000 Dec 29;275(52):41201-9.

20.

A GTPase-independent mechanism of p21-activated kinase activation. Regulation by sphingosine and other biologically active lipids.

Bokoch GM, Reilly AM, Daniels RH, King CC, Olivera A, Spiegel S, Knaus UG.

J Biol Chem. 1998 Apr 3;273(14):8137-44.

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