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Items: 1 to 20 of 103


Tissue-specific histone modification and transcription factor binding in alpha globin gene expression.

De Gobbi M, Anguita E, Hughes J, Sloane-Stanley JA, Sharpe JA, Koch CM, Dunham I, Gibbons RJ, Wood WG, Higgs DR.

Blood. 2007 Dec 15;110(13):4503-10. Epub 2007 Aug 22. Erratum in: Blood. 2008 Feb 15;111(4):1773.


Identification of a conserved erythroid specific domain of histone acetylation across the alpha-globin gene cluster.

Anguita E, Johnson CA, Wood WG, Turner BM, Higgs DR.

Proc Natl Acad Sci U S A. 2001 Oct 9;98(21):12114-9. Epub 2001 Oct 2.


Transcriptional activation of human zeta 2 globin promoter by the alpha globin regulatory element (HS-40): functional role of specific nuclear factor-DNA complexes.

Zhang Q, Reddy PM, Yu CY, Bastiani C, Higgs D, Stamatoyannopoulos G, Papayannopoulou T, Shen CK.

Mol Cell Biol. 1993 Apr;13(4):2298-308.


Genomic footprinting and sequencing of human beta-globin locus. Tissue specificity and cell line artifact.

Reddy PM, Stamatoyannopoulos G, Papayannopoulou T, Shen CK.

J Biol Chem. 1994 Mar 18;269(11):8287-95.


Dynamics of alpha-globin locus chromatin structure and gene expression during erythroid differentiation of human CD34(+) cells in culture.

Mahajan MC, Karmakar S, Newburger PE, Krause DS, Weissman SM.

Exp Hematol. 2009 Oct;37(10):1143-1156.e3. doi: 10.1016/j.exphem.2009.07.001. Epub 2009 Jul 14.


Epigenetic analysis of the human alpha- and beta-globin gene clusters.

Fathallah H, Portnoy G, Atweh GF.

Blood Cells Mol Dis. 2008 Mar-Apr;40(2):166-73. Epub 2007 Oct 29.


Formation of a tissue-specific histone acetylation pattern by the hematopoietic transcription factor GATA-1.

Letting DL, Rakowski C, Weiss MJ, Blobel GA.

Mol Cell Biol. 2003 Feb;23(4):1334-40.


A major role for the TATA box in recruitment of chromatin modifying complexes to a globin gene promoter.

Gui CY, Dean A.

Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7009-14. Epub 2003 May 28.


Methylation of alpha-type embryonic globin gene alpha pi represses transcription in primary erythroid cells.

Singal R, vanWert JM, Ferdinand L Jr.

Blood. 2002 Dec 1;100(12):4217-22. Epub 2002 Aug 1.


Activation of beta-major globin gene transcription is associated with recruitment of NF-E2 to the beta-globin LCR and gene promoter.

Sawado T, Igarashi K, Groudine M.

Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10226-31. Epub 2001 Aug 21.


Sequences located 3' to the breakpoint of the hereditary persistence of fetal hemoglobin-3 deletion exhibit enhancer activity and can modify the developmental expression of the human fetal A gamma-globin gene in transgenic mice.

Anagnou NP, Perez-Stable C, Gelinas R, Costantini F, Liapaki K, Constantopoulou M, Kosteas T, Moschonas NK, Stamatoyannopoulos G.

J Biol Chem. 1995 Apr 28;270(17):10256-63.


Heme-dependent up-regulation of the alpha-globin gene expression by transcriptional repressor Bach1 in erythroid cells.

Tahara T, Sun J, Igarashi K, Taketani S.

Biochem Biophys Res Commun. 2004 Nov 5;324(1):77-85.


Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA-1 and GATA-2.

Anguita E, Hughes J, Heyworth C, Blobel GA, Wood WG, Higgs DR.

EMBO J. 2004 Jul 21;23(14):2841-52. Epub 2004 Jun 24.


Developmental stage differences in chromatin subdomains of the beta-globin locus.

Kim A, Dean A.

Proc Natl Acad Sci U S A. 2004 May 4;101(18):7028-33. Epub 2004 Apr 22.


Loading of DNA-binding factors to an erythroid enhancer.

Wen SC, Roder K, Hu KY, Rombel I, Gavva NR, Daftari P, Kuo YY, Wang C, Shen CK.

Mol Cell Biol. 2000 Mar;20(6):1993-2003.


Targeted deletion of the chicken beta-globin regulatory elements reveals a cooperative gene silencing activity.

Wang J, Liu H, Lin CM, Aladjem MI, Epner EM.

J Biol Chem. 2005 Jun 17;280(24):23340-8. Epub 2005 Apr 11.

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