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CWH43 is required for the introduction of ceramides into GPI anchors in Saccharomyces cerevisiae.

Ghugtyal V, Vionnet C, Roubaty C, Conzelmann A.

Mol Microbiol. 2007 Sep;65(6):1493-502. Epub 2007 Aug 21.


Saccharomyces cerevisiae CWH43 is involved in the remodeling of the lipid moiety of GPI anchors to ceramides.

Umemura M, Fujita M, Yoko-O T, Fukamizu A, Jigami Y.

Mol Biol Cell. 2007 Nov;18(11):4304-16. Epub 2007 Aug 29.


Incorporation of ceramides into Saccharomyces cerevisiae glycosylphosphatidylinositol-anchored proteins can be monitored in vitro.

Bosson R, Guillas I, Vionnet C, Roubaty C, Conzelmann A.

Eukaryot Cell. 2009 Mar;8(3):306-14. doi: 10.1128/EC.00257-08. Epub 2008 Dec 12.


PER1 is required for GPI-phospholipase A2 activity and involved in lipid remodeling of GPI-anchored proteins.

Fujita M, Umemura M, Yoko-o T, Jigami Y.

Mol Biol Cell. 2006 Dec;17(12):5253-64. Epub 2006 Oct 4.


Determination and physiological roles of the glycosylphosphatidylinositol lipid remodelling pathway in yeast.

Yoko-O T, Ichikawa D, Miyagishi Y, Kato A, Umemura M, Takase K, Ra M, Ikeda K, Taguchi R, Jigami Y.

Mol Microbiol. 2013 Apr;88(1):140-55. doi: 10.1111/mmi.12175. Epub 2013 Mar 6.


Chemogenetic E-MAP in Saccharomyces cerevisiae for Identification of Membrane Transporters Operating Lipid Flip Flop.

Vazquez HM, Vionnet C, Roubaty C, Mallela SK, Schneiter R, Conzelmann A.

PLoS Genet. 2016 Jul 27;12(7):e1006160. doi: 10.1371/journal.pgen.1006160. eCollection 2016 Jul.


Inositol deacylation of glycosylphosphatidylinositol-anchored proteins is mediated by mammalian PGAP1 and yeast Bst1p.

Tanaka S, Maeda Y, Tashima Y, Kinoshita T.

J Biol Chem. 2004 Apr 2;279(14):14256-63. Epub 2004 Jan 20.


GUP1 of Saccharomyces cerevisiae encodes an O-acyltransferase involved in remodeling of the GPI anchor.

Bosson R, Jaquenoud M, Conzelmann A.

Mol Biol Cell. 2006 Jun;17(6):2636-45. Epub 2006 Apr 5.


The Gup1 homologue of Trypanosoma brucei is a GPI glycosylphosphatidylinositol remodelase.

Jaquenoud M, Pagac M, Signorell A, Benghezal M, Jelk J, Bütikofer P, Conzelmann A.

Mol Microbiol. 2008 Jan;67(1):202-12. Epub 2007 Nov 25.


C26-CoA-dependent ceramide synthesis of Saccharomyces cerevisiae is operated by Lag1p and Lac1p.

Guillas I, Kirchman PA, Chuard R, Pfefferli M, Jiang JC, Jazwinski SM, Conzelmann A.

EMBO J. 2001 Jun 1;20(11):2655-65.


MCD4 encodes a conserved endoplasmic reticulum membrane protein essential for glycosylphosphatidylinositol anchor synthesis in yeast.

Gaynor EC, Mondésert G, Grimme SJ, Reed SI, Orlean P, Emr SD.

Mol Biol Cell. 1999 Mar;10(3):627-48.


Yeast cells lacking all known ceramide synthases continue to make complex sphingolipids and to incorporate ceramides into glycosylphosphatidylinositol (GPI) anchors.

Vionnet C, Roubaty C, Ejsing CS, Knudsen J, Conzelmann A.

J Biol Chem. 2011 Feb 25;286(8):6769-79. doi: 10.1074/jbc.M110.176875. Epub 2010 Dec 20.


Inositol deacylation by Bst1p is required for the quality control of glycosylphosphatidylinositol-anchored proteins.

Fujita M, Yoko-O T, Jigami Y.

Mol Biol Cell. 2006 Feb;17(2):834-50. Epub 2005 Nov 30.


Ceramide synthesis enhances transport of GPI-anchored proteins to the Golgi apparatus in yeast.

Horvath A, Sütterlin C, Manning-Krieg U, Movva NR, Riezman H.

EMBO J. 1994 Aug 15;13(16):3687-95.


Deletion of GPI7, a yeast gene required for addition of a side chain to the glycosylphosphatidylinositol (GPI) core structure, affects GPI protein transport, remodeling, and cell wall integrity.

Benachour A, Sipos G, Flury I, Reggiori F, Canivenc-Gansel E, Vionnet C, Conzelmann A, Benghezal M.

J Biol Chem. 1999 May 21;274(21):15251-61.

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