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Items: 1 to 20 of 143

1.

Thermodynamic analysis of additivity between the heavy and light chains in affinity maturation of an antibody.

Kang J, Warren AS.

Mol Immunol. 2008 Jan;45(1):304-5. Epub 2007 Aug 17.

PMID:
17707510
2.

Strategy for affinity maturation of an antibody with high evolvability to (4-hydroxy-3-nitrophenyl) acetyl hapten.

Furukawa K, Shimizu T, Murakami A, Kono R, Nakagawa M, Sagawa T, Yamato I, Azuma T.

Mol Immunol. 2007 Mar;44(9):2436-45. Epub 2006 Nov 21.

PMID:
17118452
3.

Unraveling the effect of changes in conformation and compactness at the antibody V(L)-V(H) interface upon antigen binding.

Pellequer JL, Chen Sw, Roberts VA, Tainer JA, Getzoff ED.

J Mol Recognit. 1999 Jul-Aug;12(4):267-75.

PMID:
10440998
4.

Enthalpy-entropy compensation in the transition of a monospecific antibody towards antigen-binding promiscuity.

Kang J, Warren AS.

Mol Immunol. 2007 Jul;44(14):3623-4. Epub 2007 Apr 25.

PMID:
17462737
5.

Genetic and fluorescence studies of affinity maturation in related antibodies.

Pauyo T, Hilinski GJ, Chiu PT, Hansen DE, Choi YJ, Ratner DI, Shah-Mahoney N, Southern CA, O'Hara PB.

Mol Immunol. 2006 Mar;43(7):812-21. Epub 2005 Aug 30.

PMID:
16137768
6.

Mutational analysis of the affinity maturation of antibody 48G7.

Yang PL, Schultz PG.

J Mol Biol. 1999 Dec 17;294(5):1191-201.

PMID:
10600377
7.

Affinity maturation increases the stability and plasticity of the Fv domain of anti-protein antibodies.

Acierno JP, Braden BC, Klinke S, Goldbaum FA, Cauerhff A.

J Mol Biol. 2007 Nov 16;374(1):130-46. Epub 2007 Sep 11.

PMID:
17916365
8.

Thermodynamic characterization of affinity maturation: the D1.3 antibody and a higher-affinity mutant.

VanAntwerp JJ, Wittrup KD.

J Mol Recognit. 1998 Winter;11(1-6):10-3.

PMID:
10076798
9.

Analysis of the individual contributions of immunoglobulin heavy and light chains to the binding of antigen using cell transfection and plasmon resonance analysis.

Noel D, Bernardi T, Navarro-Teulon I, Marin M, Martinetto JP, Ducancel F, Mani JC, Pau B, Piechaczyk M, Biard-Piechaczyk M.

J Immunol Methods. 1996 Jun 21;193(2):177-87.

PMID:
8699031
10.

Pronounced effect of hapten binding on thermal stability of an anti-(4-hydroxy-3-nitrophenyl)acetyl antibody possessing a glycine residue at position 95 of the heavy chain.

Sato Y, Inaba S, Fukada H, Azuma T, Oda M.

Mol Immunol. 2017 May;85:130-136. doi: 10.1016/j.molimm.2017.02.010. Epub 2017 Feb 27.

PMID:
28249223
11.

Thermodynamic and kinetic aspects of antibody evolution during the immune response to hapten.

Sagawa T, Oda M, Ishimura M, Furukawa K, Azuma T.

Mol Immunol. 2003 Mar;39(13):801-8.

PMID:
12617995
12.

The immunoglobulin heavy chain constant region affects kinetic and thermodynamic parameters of antibody variable region interactions with antigen.

Torres M, Fernández-Fuentes N, Fiser A, Casadevall A.

J Biol Chem. 2007 May 4;282(18):13917-27. Epub 2007 Mar 12.

13.

The affinity maturation of anti-4-hydroxy-3-nitrophenylacetyl mouse monoclonal antibody. A calorimetric study of the antigen-antibody interaction.

Torigoe H, Nakayama T, Imazato M, Shimada I, Arata Y, Sarai A.

J Biol Chem. 1995 Sep 22;270(38):22218-22.

14.

Targeting random mutations to hotspots in antibody variable domains for affinity improvement.

Chowdhury PS.

Methods Mol Biol. 2002;178:269-85. Review. No abstract available.

PMID:
11968497
15.

Conformational changes in the antibody constant domains upon hapten-binding.

Sagawa T, Oda M, Morii H, Takizawa H, Kozono H, Azuma T.

Mol Immunol. 2005 Jan;42(1):9-18.

PMID:
15488939
16.

Energy-based analysis and prediction of the orientation between light- and heavy-chain antibody variable domains.

Narayanan A, Sellers BD, Jacobson MP.

J Mol Biol. 2009 May 22;388(5):941-53. doi: 10.1016/j.jmb.2009.03.043. Epub 2009 Mar 24.

PMID:
19324053
17.
18.

Substantial energetic improvement with minimal structural perturbation in a high affinity mutant antibody.

Midelfort KS, Hernandez HH, Lippow SM, Tidor B, Drennan CL, Wittrup KD.

J Mol Biol. 2004 Oct 22;343(3):685-701.

PMID:
15465055
19.

Exploring the energy landscape of antibody-antigen complexes: protein dynamics, flexibility, and molecular recognition.

Thielges MC, Zimmermann J, Yu W, Oda M, Romesberg FE.

Biochemistry. 2008 Jul 8;47(27):7237-47. doi: 10.1021/bi800374q. Epub 2008 Jun 13.

PMID:
18549243
20.

Functional heavy-chain antibodies in Camelidae.

Nguyen VK, Desmyter A, Muyldermans S.

Adv Immunol. 2001;79:261-96. Review. No abstract available.

PMID:
11680009

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