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Items: 1 to 20 of 207

1.

Oxidized phospholipids induce phenotypic switching of vascular smooth muscle cells in vivo and in vitro.

Pidkovka NA, Cherepanova OA, Yoshida T, Alexander MR, Deaton RA, Thomas JA, Leitinger N, Owens GK.

Circ Res. 2007 Oct 12;101(8):792-801. Epub 2007 Aug 17.

2.

Kruppel-like factor 4, Elk-1, and histone deacetylases cooperatively suppress smooth muscle cell differentiation markers in response to oxidized phospholipids.

Yoshida T, Gan Q, Owens GK.

Am J Physiol Cell Physiol. 2008 Nov;295(5):C1175-82. doi: 10.1152/ajpcell.00288.2008. Epub 2008 Sep 3.

3.

Oxidized phospholipids induce type VIII collagen expression and vascular smooth muscle cell migration.

Cherepanova OA, Pidkovka NA, Sarmento OF, Yoshida T, Gan Q, Adiguzel E, Bendeck MP, Berliner J, Leitinger N, Owens GK.

Circ Res. 2009 Mar 13;104(5):609-18. doi: 10.1161/CIRCRESAHA.108.186064. Epub 2009 Jan 22.

4.

Sp1-dependent activation of KLF4 is required for PDGF-BB-induced phenotypic modulation of smooth muscle.

Deaton RA, Gan Q, Owens GK.

Am J Physiol Heart Circ Physiol. 2009 Apr;296(4):H1027-37. doi: 10.1152/ajpheart.01230.2008. Epub 2009 Jan 23.

5.

Kruppel-like factor 4 abrogates myocardin-induced activation of smooth muscle gene expression.

Liu Y, Sinha S, McDonald OG, Shang Y, Hoofnagle MH, Owens GK.

J Biol Chem. 2005 Mar 11;280(10):9719-27. Epub 2004 Dec 28.

6.

Oxidized phospholipids in minimally modified low density lipoprotein induce apoptotic signaling via activation of acid sphingomyelinase in arterial smooth muscle cells.

Loidl A, Sevcsik E, Riesenhuber G, Deigner HP, Hermetter A.

J Biol Chem. 2003 Aug 29;278(35):32921-8. Epub 2003 Jun 19.

7.

The oxidized phospholipids POVPC and PGPC inhibit growth and induce apoptosis in vascular smooth muscle cells.

Fruhwirth GO, Moumtzi A, Loidl A, Ingolic E, Hermetter A.

Biochim Biophys Acta. 2006 Sep;1761(9):1060-9. Epub 2006 Jul 4.

PMID:
16904371
8.

Forced expression of myocardin is not sufficient for induction of smooth muscle differentiation in multipotential embryonic cells.

Yoshida T, Kawai-Kowase K, Owens GK.

Arterioscler Thromb Vasc Biol. 2004 Sep;24(9):1596-601. Epub 2004 Jul 1.

9.
10.

Molecular mechanisms of collagen isotype-specific modulation of smooth muscle cell phenotype.

Orr AW, Lee MY, Lemmon JA, Yurdagul A Jr, Gomez MF, Bortz PD, Wamhoff BR.

Arterioscler Thromb Vasc Biol. 2009 Feb;29(2):225-31. doi: 10.1161/ATVBAHA.108.178749. Epub 2008 Nov 20.

11.
12.

Upregulation of intermediate-conductance Ca2+-activated K+ channel (IKCa1) mediates phenotypic modulation of coronary smooth muscle.

Tharp DL, Wamhoff BR, Turk JR, Bowles DK.

Am J Physiol Heart Circ Physiol. 2006 Nov;291(5):H2493-503. Epub 2006 Jun 23.

13.

Kruppel-like factor 4 contributes to high phosphate-induced phenotypic switching of vascular smooth muscle cells into osteogenic cells.

Yoshida T, Yamashita M, Hayashi M.

J Biol Chem. 2012 Jul 27;287(31):25706-14. doi: 10.1074/jbc.M112.361360. Epub 2012 Jun 7.

14.

Determinants of bioactivity of oxidized phospholipids. Specific oxidized fatty acyl groups at the sn-2 position.

Subbanagounder G, Leitinger N, Schwenke DC, Wong JW, Lee H, Rizza C, Watson AD, Faull KF, Fogelman AM, Berliner JA.

Arterioscler Thromb Vasc Biol. 2000 Oct;20(10):2248-54.

15.

Molecular control of vascular smooth muscle cell differentiation and phenotypic plasticity.

Owens GK.

Novartis Found Symp. 2007;283:174-91; discussion 191-3, 238-41. Review.

PMID:
18300422
16.

Identification of a Klf4-dependent upstream repressor region mediating transcriptional regulation of the myocardin gene in human smooth muscle cells.

Turner EC, Huang CL, Govindarajan K, Caplice NM.

Biochim Biophys Acta. 2013 Nov;1829(11):1191-201. doi: 10.1016/j.bbagrm.2013.09.002. Epub 2013 Sep 21.

PMID:
24060351
17.

Runx2 represses myocardin-mediated differentiation and facilitates osteogenic conversion of vascular smooth muscle cells.

Tanaka T, Sato H, Doi H, Yoshida CA, Shimizu T, Matsui H, Yamazaki M, Akiyama H, Kawai-Kowase K, Iso T, Komori T, Arai M, Kurabayashi M.

Mol Cell Biol. 2008 Feb;28(3):1147-60. Epub 2007 Nov 26.

18.

Kruppel-like factor 4 is required for the expression of vascular smooth muscle cell differentiation marker genes induced by all-trans retinoic acid.

Wang C, Han M, Zhao XM, Wen JK.

J Biochem. 2008 Sep;144(3):313-21. doi: 10.1093/jb/mvn068. Epub 2008 May 28.

PMID:
18511453
19.

Cyclosporine up-regulates Krüppel-like factor-4 (KLF4) in vascular smooth muscle cells and drives phenotypic modulation in vivo.

Garvey SM, Sinden DS, Schoppee Bortz PD, Wamhoff BR.

J Pharmacol Exp Ther. 2010 Apr;333(1):34-42. doi: 10.1124/jpet.109.163949. Epub 2010 Jan 20.

20.

Multiple repressor pathways contribute to phenotypic switching of vascular smooth muscle cells.

Kawai-Kowase K, Owens GK.

Am J Physiol Cell Physiol. 2007 Jan;292(1):C59-69. Epub 2006 Sep 6. Review.

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