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Items: 1 to 20 of 473

1.

Sirtuins: the 'magnificent seven', function, metabolism and longevity.

Dali-Youcef N, Lagouge M, Froelich S, Koehl C, Schoonjans K, Auwerx J.

Ann Med. 2007;39(5):335-45. Review.

PMID:
17701476
2.

Comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction".

Kaeberlein M, Steffen KK, Hu D, Dang N, Kerr EO, Tsuchiya M, Fields S, Kennedy BK.

Science. 2006 Jun 2;312(5778):1312; author reply 1312.

3.

Calorie restriction and SIR2 genes--towards a mechanism.

Guarente L.

Mech Ageing Dev. 2005 Sep;126(9):923-8. Review.

PMID:
15941577
4.

The role of NAD+ dependent histone deacetylases (sirtuins) in ageing.

Trapp J, Jung M.

Curr Drug Targets. 2006 Nov;7(11):1553-60. Review.

PMID:
17100594
5.

Sir2 and calorie restriction in yeast: a skeptical perspective.

Kaeberlein M, Powers RW 3rd.

Ageing Res Rev. 2007 Aug;6(2):128-40. Epub 2007 Apr 19. Review.

PMID:
17512264
6.

Sirtuins in aging and disease.

Guarente L.

Cold Spring Harb Symp Quant Biol. 2007;72:483-8. doi: 10.1101/sqb.2007.72.024. Review.

PMID:
18419308
7.

Human Sir2 and the 'silencing' of p53 activity.

Smith J.

Trends Cell Biol. 2002 Sep;12(9):404-6.

PMID:
12220851
8.
9.

Distinct roles of processes modulated by histone deacetylases Rpd3p, Hda1p, and Sir2p in life extension by caloric restriction in yeast.

Jiang JC, Wawryn J, Shantha Kumara HM, Jazwinski SM.

Exp Gerontol. 2002 Aug-Sep;37(8-9):1023-30.

PMID:
12213553
10.

Calorie restriction--the SIR2 connection.

Guarente L, Picard F.

Cell. 2005 Feb 25;120(4):473-82. Review.

11.

High osmolarity extends life span in Saccharomyces cerevisiae by a mechanism related to calorie restriction.

Kaeberlein M, Andalis AA, Fink GR, Guarente L.

Mol Cell Biol. 2002 Nov;22(22):8056-66.

12.

Calorie restriction increases life span: a molecular mechanism.

Wolf G.

Nutr Rev. 2006 Feb;64(2 Pt 1):89-92. Review.

PMID:
16536186
13.

The anti-aging, metabolism potential of SIRT1.

Ghosh HS.

Curr Opin Investig Drugs. 2008 Oct;9(10):1095-102. Review.

PMID:
18821472
14.

Diversity in the Sir2 family of protein deacetylases.

Buck SW, Gallo CM, Smith JS.

J Leukoc Biol. 2004 Jun;75(6):939-50. Epub 2004 Jan 23. Review.

PMID:
14742637
15.

Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction.

Haigis MC, Guarente LP.

Genes Dev. 2006 Nov 1;20(21):2913-21. Review.

16.

Sir2 blocks extreme life-span extension.

Fabrizio P, Gattazzo C, Battistella L, Wei M, Cheng C, McGrew K, Longo VD.

Cell. 2005 Nov 18;123(4):655-67.

17.

Structure and chemistry of the Sir2 family of NAD+-dependent histone/protein deactylases.

Marmorstein R.

Biochem Soc Trans. 2004 Dec;32(Pt 6):904-9. Review.

PMID:
15506920
18.

Sirtuins (histone deacetylases III) in the cellular response to DNA damage--facts and hypotheses.

Kruszewski M, Szumiel I.

DNA Repair (Amst). 2005 Nov 21;4(11):1306-13. Epub 2005 Aug 3. Review.

PMID:
16084131
19.

Function of SIRT1 in physiology.

Kong XX, Wang R, Liu XJ, Zhu LL, Shao D, Chang YS, Fang FD.

Biochemistry (Mosc). 2009 Jul;74(7):703-8. Review.

PMID:
19747089
20.

Sirtuin-targeting drugs: Mechanisms of action and potential therapeutic applications.

Aljada A, Dong L, Mousa SA.

Curr Opin Investig Drugs. 2010 Oct;11(10):1158-68. Review.

PMID:
20872319

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