Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 142

1.

RNA-binding proteins hnRNP A2/B1 and CUGBP1 suppress fragile X CGG premutation repeat-induced neurodegeneration in a Drosophila model of FXTAS.

Sofola OA, Jin P, Qin Y, Duan R, Liu H, de Haro M, Nelson DL, Botas J.

Neuron. 2007 Aug 16;55(4):565-71.

2.

Pur alpha binds to rCGG repeats and modulates repeat-mediated neurodegeneration in a Drosophila model of fragile X tremor/ataxia syndrome.

Jin P, Duan R, Qurashi A, Qin Y, Tian D, Rosser TC, Liu H, Feng Y, Warren ST.

Neuron. 2007 Aug 16;55(4):556-64.

3.

TDP-43 suppresses CGG repeat-induced neurotoxicity through interactions with HnRNP A2/B1.

He F, Krans A, Freibaum BD, Taylor JP, Todd PK.

Hum Mol Genet. 2014 Oct 1;23(19):5036-51. doi: 10.1093/hmg/ddu216. Epub 2014 May 8.

4.

Argonaute-2-dependent rescue of a Drosophila model of FXTAS by FRAXE premutation repeat.

Sofola OA, Jin P, Botas J, Nelson DL.

Hum Mol Genet. 2007 Oct 1;16(19):2326-32. Epub 2007 Jul 17.

PMID:
17635840
5.

RAN translation at CGG repeats induces ubiquitin proteasome system impairment in models of fragile X-associated tremor ataxia syndrome.

Oh SY, He F, Krans A, Frazer M, Taylor JP, Paulson HL, Todd PK.

Hum Mol Genet. 2015 Aug 1;24(15):4317-26. doi: 10.1093/hmg/ddv165. Epub 2015 May 7.

6.

Histone deacetylases suppress CGG repeat-induced neurodegeneration via transcriptional silencing in models of fragile X tremor ataxia syndrome.

Todd PK, Oh SY, Krans A, Pandey UB, Di Prospero NA, Min KT, Taylor JP, Paulson HL.

PLoS Genet. 2010 Dec 9;6(12):e1001240. doi: 10.1371/journal.pgen.1001240.

7.

Retrotransposon activation contributes to fragile X premutation rCGG-mediated neurodegeneration.

Tan H, Qurashi A, Poidevin M, Nelson DL, Li H, Jin P.

Hum Mol Genet. 2012 Jan 1;21(1):57-65. doi: 10.1093/hmg/ddr437. Epub 2011 Sep 22.

8.

MicroRNA-277 modulates the neurodegeneration caused by Fragile X premutation rCGG repeats.

Tan H, Poidevin M, Li H, Chen D, Jin P.

PLoS Genet. 2012;8(5):e1002681. doi: 10.1371/journal.pgen.1002681. Epub 2012 May 3.

9.

FMR1 CGG repeat length predicts motor dysfunction in premutation carriers.

Leehey MA, Berry-Kravis E, Goetz CG, Zhang L, Hall DA, Li L, Rice CD, Lara R, Cogswell J, Reynolds A, Gane L, Jacquemont S, Tassone F, Grigsby J, Hagerman RJ, Hagerman PJ.

Neurology. 2008 Apr 15;70(16 Pt 2):1397-402. Epub 2007 Dec 5.

10.

RNA-mediated neurodegeneration caused by the fragile X premutation rCGG repeats in Drosophila.

Jin P, Zarnescu DC, Zhang F, Pearson CE, Lucchesi JC, Moses K, Warren ST.

Neuron. 2003 Aug 28;39(5):739-47.

11.

Chemical screen reveals small molecules suppressing fragile X premutation rCGG repeat-mediated neurodegeneration in Drosophila.

Qurashi A, Liu H, Ray L, Nelson DL, Duan R, Jin P.

Hum Mol Genet. 2012 May 1;21(9):2068-75. doi: 10.1093/hmg/dds024. Epub 2012 Feb 1.

12.

Nuclear accumulation of stress response mRNAs contributes to the neurodegeneration caused by Fragile X premutation rCGG repeats.

Qurashi A, Li W, Zhou JY, Peng J, Jin P.

PLoS Genet. 2011 Jun;7(6):e1002102. doi: 10.1371/journal.pgen.1002102. Epub 2011 Jun 2.

13.

CGG repeat-associated translation mediates neurodegeneration in fragile X tremor ataxia syndrome.

Todd PK, Oh SY, Krans A, He F, Sellier C, Frazer M, Renoux AJ, Chen KC, Scaglione KM, Basrur V, Elenitoba-Johnson K, Vonsattel JP, Louis ED, Sutton MA, Taylor JP, Mills RE, Charlet-Berguerand N, Paulson HL.

Neuron. 2013 May 8;78(3):440-55. doi: 10.1016/j.neuron.2013.03.026. Epub 2013 Apr 18. Erratum in: Neuron. 2013 Jul 24;79(2):402.

14.

Blood expression profiles of fragile X premutation carriers identify candidate genes involved in neurodegenerative and infertility phenotypes.

Mateu-Huertas E, Rodriguez-Revenga L, Alvarez-Mora MI, Madrigal I, Willemsen R, MilĂ  M, MartĂ­ E, Estivill X.

Neurobiol Dis. 2014 May;65:43-54. doi: 10.1016/j.nbd.2013.12.020. Epub 2014 Jan 10.

PMID:
24418349
15.

Activation of mTOR ameliorates fragile X premutation rCGG repeat-mediated neurodegeneration.

Lin Y, Tang C, He H, Duan R.

PLoS One. 2013 Apr 23;8(4):e62572. doi: 10.1371/journal.pone.0062572. Print 2013.

16.

The fragile X-associated tremor ataxia syndrome.

Tassone F, Hagerman R.

Results Probl Cell Differ. 2012;54:337-57. doi: 10.1007/978-3-642-21649-7_18.

PMID:
22009361
17.

Cerebral protein synthesis in a knockin mouse model of the fragile X premutation.

Qin M, Huang T, Liu Z, Kader M, Burlin T, Xia Z, Zeidler Z, Hukema RK, Smith CB.

ASN Neuro. 2014 Sep 23;6(5). pii: 1759091414551957. doi: 10.1177/1759091414551957. Print 2014.

18.

CGG-repeat length threshold for FMR1 RNA pathogenesis in a cellular model for FXTAS.

Hoem G, Raske CR, Garcia-Arocena D, Tassone F, Sanchez E, Ludwig AL, Iwahashi CK, Kumar M, Yang JE, Hagerman PJ.

Hum Mol Genet. 2011 Jun 1;20(11):2161-70. doi: 10.1093/hmg/ddr101. Epub 2011 Mar 9.

19.

CNS expression of murine fragile X protein (FMRP) as a function of CGG-repeat size.

Ludwig AL, Espinal GM, Pretto DI, Jamal AL, Arque G, Tassone F, Berman RF, Hagerman PJ.

Hum Mol Genet. 2014 Jun 15;23(12):3228-38. doi: 10.1093/hmg/ddu032. Epub 2014 Jan 23.

20.

RNA-mediated neurodegeneration in fragile X-associated tremor/ataxia syndrome.

Li Y, Jin P.

Brain Res. 2012 Jun 26;1462:112-7. doi: 10.1016/j.brainres.2012.02.057. Epub 2012 Mar 9. Review.

Supplemental Content

Support Center