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Items: 1 to 20 of 465

1.

Functional consequence of protein kinase A-dependent phosphorylation of the cardiac ryanodine receptor: sensitization of store overload-induced Ca2+ release.

Xiao B, Tian X, Xie W, Jones PP, Cai S, Wang X, Jiang D, Kong H, Zhang L, Chen K, Walsh MP, Cheng H, Chen SR.

J Biol Chem. 2007 Oct 12;282(41):30256-64. Epub 2007 Aug 10.

2.

Characterization of a novel PKA phosphorylation site, serine-2030, reveals no PKA hyperphosphorylation of the cardiac ryanodine receptor in canine heart failure.

Xiao B, Jiang MT, Zhao M, Yang D, Sutherland C, Lai FA, Walsh MP, Warltier DC, Cheng H, Chen SR.

Circ Res. 2005 Apr 29;96(8):847-55. Epub 2005 Mar 24.

3.

Loss of luminal Ca2+ activation in the cardiac ryanodine receptor is associated with ventricular fibrillation and sudden death.

Jiang D, Chen W, Wang R, Zhang L, Chen SR.

Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18309-14. Epub 2007 Nov 1.

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Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol.

Reiken S, Gaburjakova M, Guatimosim S, Gomez AM, D'Armiento J, Burkhoff D, Wang J, Vassort G, Lederer WJ, Marks AR.

J Biol Chem. 2003 Jan 3;278(1):444-53. Epub 2002 Oct 24.

7.

Ca2+/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failure.

Ai X, Curran JW, Shannon TR, Bers DM, Pogwizd SM.

Circ Res. 2005 Dec 9;97(12):1314-22. Epub 2005 Nov 3.

9.

Intact beta-adrenergic response and unmodified progression toward heart failure in mice with genetic ablation of a major protein kinase A phosphorylation site in the cardiac ryanodine receptor.

Benkusky NA, Weber CS, Scherman JA, Farrell EF, Hacker TA, John MC, Powers PA, Valdivia HH.

Circ Res. 2007 Oct 12;101(8):819-29. Epub 2007 Aug 23.

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13.

The effect of PKA-mediated phosphorylation of ryanodine receptor on SR Ca2+ leak in ventricular myocytes.

Bovo E, Huke S, Blatter LA, Zima AV.

J Mol Cell Cardiol. 2017 Mar;104:9-16. doi: 10.1016/j.yjmcc.2017.01.015. Epub 2017 Jan 25.

PMID:
28131630
14.
15.

Sudden death in familial polymorphic ventricular tachycardia associated with calcium release channel (ryanodine receptor) leak.

Lehnart SE, Wehrens XH, Laitinen PJ, Reiken SR, Deng SX, Cheng Z, Landry DW, Kontula K, Swan H, Marks AR.

Circulation. 2004 Jun 29;109(25):3208-14. Epub 2004 Jun 14.

16.

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts.

Marx SO, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N, Marks AR.

Cell. 2000 May 12;101(4):365-76.

17.

PKA phosphorylation of cardiac ryanodine receptor modulates SR luminal Ca2+ sensitivity.

Ullrich ND, Valdivia HH, Niggli E.

J Mol Cell Cardiol. 2012 Jul;53(1):33-42. doi: 10.1016/j.yjmcc.2012.03.015. Epub 2012 Apr 1.

18.

Ryanodine receptors, FKBP12, and heart failure.

Marks AR.

Front Biosci. 2002 Apr 1;7:d970-7. Review.

PMID:
11897558
19.

RyR2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca2+ release (SOICR).

Jiang D, Xiao B, Yang D, Wang R, Choi P, Zhang L, Cheng H, Chen SR.

Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):13062-7. Epub 2004 Aug 20.

20.

Dyssynchronous (non-uniform) Ca2+ release in myocytes from streptozotocin-induced diabetic rats.

Shao CH, Rozanski GJ, Patel KP, Bidasee KR.

J Mol Cell Cardiol. 2007 Jan;42(1):234-46. Epub 2006 Oct 6.

PMID:
17027851

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