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Items: 1 to 20 of 215

1.

The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4.

Brüstle A, Heink S, Huber M, Rosenplänter C, Stadelmann C, Yu P, Arpaia E, Mak TW, Kamradt T, Lohoff M.

Nat Immunol. 2007 Sep;8(9):958-66. Epub 2007 Aug 5.

PMID:
17676043
2.

Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells.

Acosta-Rodriguez EV, Napolitani G, Lanzavecchia A, Sallusto F.

Nat Immunol. 2007 Sep;8(9):942-9. Epub 2007 Aug 5.

PMID:
17676045
3.

A Th17-like developmental process leads to CD8(+) Tc17 cells with reduced cytotoxic activity.

Huber M, Heink S, Grothe H, Guralnik A, Reinhard K, Elflein K, Hünig T, Mittrücker HW, Brüstle A, Kamradt T, Lohoff M.

Eur J Immunol. 2009 Jul;39(7):1716-25. doi: 10.1002/eji.200939412.

4.

IL-6-gp130-STAT3 in T cells directs the development of IL-17+ Th with a minimum effect on that of Treg in the steady state.

Nishihara M, Ogura H, Ueda N, Tsuruoka M, Kitabayashi C, Tsuji F, Aono H, Ishihara K, Huseby E, Betz UA, Murakami M, Hirano T.

Int Immunol. 2007 Jun;19(6):695-702. Epub 2007 May 9.

PMID:
17493959
5.

IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype.

Huber M, Brüstle A, Reinhard K, Guralnik A, Walter G, Mahiny A, von Löw E, Lohoff M.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20846-51. doi: 10.1073/pnas.0809077106. Epub 2008 Dec 16.

6.

Gfi1 negatively regulates T(h)17 differentiation by inhibiting RORgammat activity.

Ichiyama K, Hashimoto M, Sekiya T, Nakagawa R, Wakabayashi Y, Sugiyama Y, Komai K, Saba I, Möröy T, Yoshimura A.

Int Immunol. 2009 Jul;21(7):881-9. doi: 10.1093/intimm/dxp054. Epub 2009 Jun 7.

PMID:
19505891
7.

Regulation of T helper 17 differentiation by orphan nuclear receptors: it's not just ROR gamma t anymore.

Sundrud MS, Rao A.

Immunity. 2008 Jan;28(1):5-7. doi: 10.1016/j.immuni.2007.12.006.

8.

The Th17/Treg imbalance in patients with acute coronary syndrome.

Cheng X, Yu X, Ding YJ, Fu QQ, Xie JJ, Tang TT, Yao R, Chen Y, Liao YH.

Clin Immunol. 2008 Apr;127(1):89-97. doi: 10.1016/j.clim.2008.01.009. Epub 2008 Feb 21. Erratum in: Clin Immunol. 2009 Dec;133(3):447.

PMID:
18294918
9.

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells.

Ivanov II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, Lafaille JJ, Cua DJ, Littman DR.

Cell. 2006 Sep 22;126(6):1121-33.

10.

Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.

Sutton CE, Lalor SJ, Sweeney CM, Brereton CF, Lavelle EC, Mills KH.

Immunity. 2009 Aug 21;31(2):331-41. doi: 10.1016/j.immuni.2009.08.001. Epub 2009 Aug 13.

11.

IL-21 and IL-21R are not required for development of Th17 cells and autoimmunity in vivo.

Sonderegger I, Kisielow J, Meier R, King C, Kopf M.

Eur J Immunol. 2008 Jul;38(7):1833-8. doi: 10.1002/eji.200838511.

12.

Development, cytokine profile and function of human interleukin 17-producing helper T cells.

Wilson NJ, Boniface K, Chan JR, McKenzie BS, Blumenschein WM, Mattson JD, Basham B, Smith K, Chen T, Morel F, Lecron JC, Kastelein RA, Cua DJ, McClanahan TK, Bowman EP, de Waal Malefyt R.

Nat Immunol. 2007 Sep;8(9):950-7. Epub 2007 Aug 5.

PMID:
17676044
13.

Effects of leukotriene B4 and prostaglandin E2 on the differentiation of murine Foxp3+ T regulatory cells and Th17 cells.

Chen H, Qin J, Wei P, Zhang J, Li Q, Fu L, Li S, Ma C, Cong B.

Prostaglandins Leukot Essent Fatty Acids. 2009 Apr;80(4):195-200. doi: 10.1016/j.plefa.2009.01.006. Epub 2009 Mar 4.

PMID:
19264469
14.

Protein kinase B/Akt signals impair Th17 differentiation and support natural regulatory T cell function and induced regulatory T cell formation.

Pierau M, Engelmann S, Reinhold D, Lapp T, Schraven B, Bommhardt UH.

J Immunol. 2009 Nov 15;183(10):6124-34. doi: 10.4049/jimmunol.0900246. Epub 2009 Oct 19.

15.

Differentiation and functional analysis of human T(H)17 cells.

Burgler S, Ouaked N, Bassin C, Basinski TM, Mantel PY, Siegmund K, Meyer N, Akdis CA, Schmidt-Weber CB.

J Allergy Clin Immunol. 2009 Mar;123(3):588-95, 595.e1-7. doi: 10.1016/j.jaci.2008.12.017.

PMID:
19178935
16.

Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells.

Staudt V, Bothur E, Klein M, Lingnau K, Reuter S, Grebe N, Gerlitzki B, Hoffmann M, Ulges A, Taube C, Dehzad N, Becker M, Stassen M, Steinborn A, Lohoff M, Schild H, Schmitt E, Bopp T.

Immunity. 2010 Aug 27;33(2):192-202. doi: 10.1016/j.immuni.2010.07.014. Epub 2010 Jul 30.

17.

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma.

Yang XO, Pappu BP, Nurieva R, Akimzhanov A, Kang HS, Chung Y, Ma L, Shah B, Panopoulos AD, Schluns KS, Watowich SS, Tian Q, Jetten AM, Dong C.

Immunity. 2008 Jan;28(1):29-39. doi: 10.1016/j.immuni.2007.11.016. Epub 2007 Dec 27.

18.

Elevated interferon regulatory factor 4 levels in patients with allergic asthma.

Chen X, Gao YD, Yang J.

J Asthma. 2012 Jun;49(5):441-9. doi: 10.3109/02770903.2012.674998. Epub 2012 Apr 19.

PMID:
22515488
19.

Immunology: narcissistic helpers.

Palmer MT, Weaver CT.

Nature. 2007 Jul 26;448(7152):416-8. No abstract available.

PMID:
17653176
20.

Synthetic retinoid AM80 inhibits Th17 cells and ameliorates experimental autoimmune encephalomyelitis.

Klemann C, Raveney BJ, Klemann AK, Ozawa T, von Hörsten S, Shudo K, Oki S, Yamamura T.

Am J Pathol. 2009 Jun;174(6):2234-45. doi: 10.2353/ajpath.2009.081084. Epub 2009 Apr 23.

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