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Items: 1 to 20 of 366

1.

The transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival.

Schneider L, Essmann F, Kletke A, Rio P, Hanenberg H, Wetzel W, Schulze-Osthoff K, Nürnberg B, Piekorz RP.

J Biol Chem. 2007 Oct 5;282(40):29273-83. Epub 2007 Aug 5.

2.

Identification of two novel components of the human NDC80 kinetochore complex.

Bharadwaj R, Qi W, Yu H.

J Biol Chem. 2004 Mar 26;279(13):13076-85. Epub 2003 Dec 29.

3.

TACC3 depletion sensitizes to paclitaxel-induced cell death and overrides p21WAF-mediated cell cycle arrest.

Schneider L, Essmann F, Kletke A, Rio P, Hanenberg H, Schulze-Osthoff K, Nürnberg B, Piekorz RP.

Oncogene. 2008 Jan 3;27(1):116-25. Epub 2007 Jun 25.

PMID:
17599038
4.

Silencing Cenp-F weakens centromeric cohesion, prevents chromosome alignment and activates the spindle checkpoint.

Holt SV, Vergnolle MA, Hussein D, Wozniak MJ, Allan VJ, Taylor SS.

J Cell Sci. 2005 Oct 15;118(Pt 20):4889-900.

5.

Self-assembly and sorting of acentrosomal microtubules by TACC3 facilitate kinetochore capture during the mitotic spindle assembly.

Fu W, Chen H, Wang G, Luo J, Deng Z, Xin G, Xu N, Guo X, Lei J, Jiang Q, Zhang C.

Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15295-300. doi: 10.1073/pnas.1312382110. Epub 2013 Sep 3.

6.

RAMA1 is a novel kinetochore protein involved in kinetochore-microtubule attachment.

Raaijmakers JA, Tanenbaum ME, Maia AF, Medema RH.

J Cell Sci. 2009 Jul 15;122(Pt 14):2436-45. doi: 10.1242/jcs.051912. Epub 2009 Jun 23.

7.

Hec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint control.

Lin YT, Chen Y, Wu G, Lee WH.

Oncogene. 2006 Nov 2;25(52):6901-14. Epub 2006 May 29.

PMID:
16732327
8.

Nucleophosmin is required for chromosome congression, proper mitotic spindle formation, and kinetochore-microtubule attachment in HeLa cells.

Amin MA, Matsunaga S, Uchiyama S, Fukui K.

FEBS Lett. 2008 Nov 12;582(27):3839-44. doi: 10.1016/j.febslet.2008.10.023. Epub 2008 Oct 23.

9.

The centrosomal protein TACC3 controls paclitaxel sensitivity by modulating a premature senescence program.

Schmidt S, Schneider L, Essmann F, Cirstea IC, Kuck F, Kletke A, Jänicke RU, Wiek C, Hanenberg H, Ahmadian MR, Schulze-Osthoff K, Nürnberg B, Piekorz RP.

Oncogene. 2010 Nov 18;29(46):6184-92. doi: 10.1038/onc.2010.354. Epub 2010 Aug 23.

PMID:
20729911
10.

Downregulation of protein 4.1R, a mature centriole protein, disrupts centrosomes, alters cell cycle progression, and perturbs mitotic spindles and anaphase.

Krauss SW, Spence JR, Bahmanyar S, Barth AI, Go MM, Czerwinski D, Meyer AJ.

Mol Cell Biol. 2008 Apr;28(7):2283-94. doi: 10.1128/MCB.02021-07. Epub 2008 Jan 22.

11.

The nuclear scaffold protein SAF-A is required for kinetochore-microtubule attachment and contributes to the targeting of Aurora-A to mitotic spindles.

Ma N, Matsunaga S, Morimoto A, Sakashita G, Urano T, Uchiyama S, Fukui K.

J Cell Sci. 2011 Feb 1;124(Pt 3):394-404. doi: 10.1242/jcs.063347.

12.

Mammalian CLASPs are required for mitotic spindle organization and kinetochore alignment.

Mimori-Kiyosue Y, Grigoriev I, Sasaki H, Matsui C, Akhmanova A, Tsukita S, Vorobjev I.

Genes Cells. 2006 Aug;11(8):845-57.

13.

Mitotic spindle checkpoint inactivation by trichostatin a defines a mechanism for increasing cancer cell killing by microtubule-disrupting agents.

Dowling M, Voong KR, Kim M, Keutmann MK, Harris E, Kao GD.

Cancer Biol Ther. 2005 Feb;4(2):197-206. Epub 2005 Feb 8.

PMID:
15753652
14.

TOGp regulates microtubule assembly and density during mitosis and contributes to chromosome directional instability.

Cassimeris L, Becker B, Carney B.

Cell Motil Cytoskeleton. 2009 Aug;66(8):535-45. doi: 10.1002/cm.20359.

PMID:
19373773
15.

Mitotic catastrophe and cell death induced by depletion of centrosomal proteins.

Kimura M, Yoshioka T, Saio M, Banno Y, Nagaoka H, Okano Y.

Cell Death Dis. 2013 Apr 18;4:e603. doi: 10.1038/cddis.2013.108.

16.

The Xenopus TACC homologue, maskin, functions in mitotic spindle assembly.

O'Brien LL, Albee AJ, Liu L, Tao W, Dobrzyn P, Lizarraga SB, Wiese C.

Mol Biol Cell. 2005 Jun;16(6):2836-47. Epub 2005 Mar 23.

17.

Identification of a novel centrosome/microtubule-associated coiled-coil protein involved in cell-cycle progression and spindle organization.

Patzke S, Hauge H, Sioud M, Finne EF, Sivertsen EA, Delabie J, Stokke T, Aasheim HC.

Oncogene. 2005 Feb 10;24(7):1159-73.

PMID:
15580290
18.

The chromosomal passenger complex controls spindle checkpoint function independent from its role in correcting microtubule kinetochore interactions.

Vader G, Cruijsen CW, van Harn T, Vromans MJ, Medema RH, Lens SM.

Mol Biol Cell. 2007 Nov;18(11):4553-64. Epub 2007 Aug 15.

19.

BubR1 is required for a sustained mitotic spindle checkpoint arrest in human cancer cells treated with tubulin-targeting pyrrolo-1,5-benzoxazepines.

Greene LM, Campiani G, Lawler M, Williams DC, Zisterer DM.

Mol Pharmacol. 2008 Feb;73(2):419-30. Epub 2007 Nov 8.

20.

Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function.

Fortugno P, Wall NR, Giodini A, O'Connor DS, Plescia J, Padgett KM, Tognin S, Marchisio PC, Altieri DC.

J Cell Sci. 2002 Feb 1;115(Pt 3):575-85.

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