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A human scFv antibody against TRAIL receptor 2 induces autophagic cell death in both TRAIL-sensitive and TRAIL-resistant cancer cells.

Park KJ, Lee SH, Kim TI, Lee HW, Lee CH, Kim EH, Jang JY, Choi KS, Kwon MH, Kim YS.

Cancer Res. 2007 Aug 1;67(15):7327-34.


Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs.

Ganten TM, Haas TL, Sykora J, Stahl H, Sprick MR, Fas SC, Krueger A, Weigand MA, Grosse-Wilde A, Stremmel W, Krammer PH, Walczak H.

Cell Death Differ. 2004 Jul;11 Suppl 1:S86-96.


Proteasome inhibitors-mediated TRAIL resensitization and Bik accumulation.

Zhu H, Guo W, Zhang L, Wu S, Teraishi F, Davis JJ, Dong F, Fang B.

Cancer Biol Ther. 2005 Jul;4(7):781-6. Epub 2005 Jul 6.


Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand.

Mitsiades N, Poulaki V, Tseleni-Balafouta S, Koutras DA, Stamenkovic I.

Cancer Res. 2000 Aug 1;60(15):4122-9.


Isogambogenic acid induces apoptosis-independent autophagic cell death in human non-small-cell lung carcinoma cells.

Yang J, Zhou Y, Cheng X, Fan Y, He S, Li S, Ye H, Xie C, Wu W, Li C, Pei H, Li L, Wei Z, Peng A, Wei Y, Li W, Chen L.

Sci Rep. 2015 Jan 9;5:7697. doi: 10.1038/srep07697.


Protein kinase C modulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by targeting the apical events of death receptor signaling.

Harper N, Hughes MA, Farrow SN, Cohen GM, MacFarlane M.

J Biol Chem. 2003 Nov 7;278(45):44338-47. Epub 2003 Aug 14.


Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis.

Clancy L, Mruk K, Archer K, Woelfel M, Mongkolsapaya J, Screaton G, Lenardo MJ, Chan FK.

Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):18099-104. Epub 2005 Nov 30.


Human astrocytes are resistant to Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis.

Song JH, Bellail A, Tse MC, Yong VW, Hao C.

J Neurosci. 2006 Mar 22;26(12):3299-308. Erratum in: J Neurosci. 2006 May 3;26(18):4983.


The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase.

Lin Y, Devin A, Cook A, Keane MM, Kelliher M, Lipkowitz S, Liu ZG.

Mol Cell Biol. 2000 Sep;20(18):6638-45.


Attenuation of TNFSF10/TRAIL-induced apoptosis by an autophagic survival pathway involving TRAF2- and RIPK1/RIP1-mediated MAPK8/JNK activation.

He W, Wang Q, Xu J, Xu X, Padilla MT, Ren G, Gou X, Lin Y.

Autophagy. 2012 Dec;8(12):1811-21. doi: 10.4161/auto.22145. Epub 2012 Oct 10.


Receptor-mediated endocytosis is not required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis.

Kohlhaas SL, Craxton A, Sun XM, Pinkoski MJ, Cohen GM.

J Biol Chem. 2007 Apr 27;282(17):12831-41. Epub 2007 Feb 27.


TRAIL-mediated apoptosis requires NF-kappaB inhibition and the mitochondrial permeability transition in human hepatoma cells.

Kim YS, Schwabe RF, Qian T, Lemasters JJ, Brenner DA.

Hepatology. 2002 Dec;36(6):1498-508.


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