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Items: 1 to 20 of 217

1.

Bendamustine induces G2 cell cycle arrest and apoptosis in myeloma cells: the role of ATM-Chk2-Cdc25A and ATM-p53-p21-pathways.

Gaul L, Mandl-Weber S, Baumann P, Emmerich B, Schmidmaier R.

J Cancer Res Clin Oncol. 2008 Feb;134(2):245-53. Epub 2007 Jul 25.

PMID:
17653574
2.

Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells.

Tyagi A, Singh RP, Agarwal C, Siriwardana S, Sclafani RA, Agarwal R.

Carcinogenesis. 2005 Nov;26(11):1978-87. Epub 2005 Jun 23.

PMID:
15975956
3.

Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways.

Ouyang G, Yao L, Ruan K, Song G, Mao Y, Bao S.

Cell Biol Int. 2009 Dec;33(12):1237-44. doi: 10.1016/j.cellbi.2009.08.011. Epub 2009 Sep 2.

PMID:
19732843
4.

Induction of G2/M arrest by pseudolaric acid B is mediated by activation of the ATM signaling pathway.

Meng AG, Jiang LL.

Acta Pharmacol Sin. 2009 Apr;30(4):442-50. doi: 10.1038/aps.2009.20. Epub 2009 Mar 23.

6.

Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional.

Lossaint G, Besnard E, Fisher D, Piette J, Dulić V.

Oncogene. 2011 Oct 13;30(41):4261-74. doi: 10.1038/onc.2011.135. Epub 2011 May 2.

PMID:
21532626
7.

Elevated cyclin G2 expression intersects with DNA damage checkpoint signaling and is required for a potent G2/M checkpoint arrest response to doxorubicin.

Zimmermann M, Arachchige-Don AS, Donaldson MS, Dallapiazza RF, Cowan CE, Horne MC.

J Biol Chem. 2012 Jun 29;287(27):22838-53. doi: 10.1074/jbc.M112.376855. Epub 2012 May 15.

8.

Kotomolide A arrests cell cycle progression and induces apoptosis through the induction of ATM/p53 and the initiation of mitochondrial system in human non-small cell lung cancer A549 cells.

Chen CY, Hsu YL, Tsai YC, Kuo PL.

Food Chem Toxicol. 2008 Jul;46(7):2476-84. doi: 10.1016/j.fct.2008.04.016. Epub 2008 Apr 22.

PMID:
18511169
9.

Widdrol activates DNA damage checkpoint through the signaling Chk2-p53-Cdc25A-p21-MCM4 pathway in HT29 cells.

Yun HJ, Hyun SK, Park JH, Kim BW, Kwon HJ.

Mol Cell Biochem. 2012 Apr;363(1-2):281-9. doi: 10.1007/s11010-011-1180-z. Epub 2011 Dec 11.

PMID:
22160829
10.

Etoposide induces G2/M arrest and apoptosis in neural progenitor cells via DNA damage and an ATM/p53-related pathway.

Nam C, Doi K, Nakayama H.

Histol Histopathol. 2010 Apr;25(4):485-93. doi: 10.14670/HH-25.485.

PMID:
20183801
11.

Ataxia telangiectasia-mutated-Rad3-related DNA damage checkpoint signaling pathway triggered by hepatitis B virus infection.

Zhao F, Hou NB, Yang XL, He X, Liu Y, Zhang YH, Wei CW, Song T, Li L, Ma QJ, Zhong H.

World J Gastroenterol. 2008 Oct 28;14(40):6163-70.

12.
13.

Ethanol metabolism activates cell cycle checkpoint kinase, Chk2.

Clemens DL, Schneider KJ, Nuss RF.

Alcohol. 2011 Dec;45(8):785-93. doi: 10.1016/j.alcohol.2011.07.005. Epub 2011 Sep 15.

14.

Genistein arrests hepatoma cells at G2/M phase: involvement of ATM activation and upregulation of p21waf1/cip1 and Wee1.

Chang KL, Kung ML, Chow NH, Su SJ.

Biochem Pharmacol. 2004 Feb 15;67(4):717-26.

PMID:
14757171
15.

Arsenic trioxide augments Chk2/p53-mediated apoptosis by inhibiting oncogenic Wip1 phosphatase.

Yoda A, Toyoshima K, Watanabe Y, Onishi N, Hazaka Y, Tsukuda Y, Tsukada J, Kondo T, Tanaka Y, Minami Y.

J Biol Chem. 2008 Jul 4;283(27):18969-79. doi: 10.1074/jbc.M800560200. Epub 2008 May 15.

16.

UCN-01 induces S and G2/M cell cycle arrest through the p53/p21(waf1) or CHK2/CDC25C pathways and can suppress invasion in human hepatoma cell lines.

Wu G, Lin N, Xu L, Liu B, Feitelson MA.

BMC Cancer. 2013 Mar 28;13:167. doi: 10.1186/1471-2407-13-167. Erratum in: BMC Cancer. 2014;14:216. Feitelson, Mark A [added].

17.

Bortezomib induces G2-M arrest in human colon cancer cells through ROS-inducible phosphorylation of ATM-CHK1.

Hong YS, Hong SW, Kim SM, Jin DH, Shin JS, Yoon DH, Kim KP, Lee JL, Heo DS, Lee JS, Kim TW.

Int J Oncol. 2012 Jul;41(1):76-82. doi: 10.3892/ijo.2012.1448. Epub 2012 Apr 26.

PMID:
22552540
18.

RAC1 GTPase plays an important role in γ-irradiation induced G2/M checkpoint activation.

Yan Y, Greer PM, Cao PT, Kolb RH, Cowan KH.

Breast Cancer Res. 2012 Apr 11;14(2):R60.

19.

Irradiation-induced G2/M checkpoint response requires ERK1/2 activation.

Yan Y, Black CP, Cowan KH.

Oncogene. 2007 Jul 12;26(32):4689-98. Epub 2007 Feb 5.

PMID:
17297454
20.

ATM/ATR-related checkpoint signals mediate arsenite-induced G2/M arrest in primary aortic endothelial cells.

Tsou TC, Tsai FY, Yeh SC, Chang LW.

Arch Toxicol. 2006 Dec;80(12):804-10.

PMID:
16645841

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