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Items: 1 to 20 of 305

1.

Targetability of human disease genes.

Sakharkar MK, Sakharkar KR.

Curr Drug Discov Technol. 2007 Jun;4(1):48-58. Review.

PMID:
17630928
2.

Druggability of human disease genes.

Sakharkar MK, Sakharkar KR, Pervaiz S.

Int J Biochem Cell Biol. 2007;39(6):1156-64. Epub 2007 Mar 7.

PMID:
17446117
3.

Biocomputational strategies for microbial drug target identification.

Sakharkar KR, Sakharkar MK, Chow VT.

Methods Mol Med. 2008;142:1-9. doi: 10.1007/978-1-59745-246-5_1.

PMID:
18437301
4.

Using bioinformatics for drug target identification from the genome.

Jiang Z, Zhou Y.

Am J Pharmacogenomics. 2005;5(6):387-96. Review.

PMID:
16336003
5.

Disease gene discovery through integrative genomics.

Giallourakis C, Henson C, Reich M, Xie X, Mootha VK.

Annu Rev Genomics Hum Genet. 2005;6:381-406. Review.

PMID:
16124867
6.

Genome-wide identification of genes likely to be involved in human genetic disease.

López-Bigas N, Ouzounis CA.

Nucleic Acids Res. 2004 Jun 4;32(10):3108-14. Print 2004.

7.
8.

Comparative genomics for detecting human disease genes.

Moreno C, Lazar J, Jacob HJ, Kwitek AE.

Adv Genet. 2008;60:655-97. doi: 10.1016/S0065-2660(07)00423-3. Review.

PMID:
18358336
10.

[Prospects of medicinal use of achievements in genomics: the beginning of era of complete genome medical genetics].

Sverdlov ED.

Patol Fiziol Eksp Ter. 2001 Jan-Mar;(1):3-22. Review. Russian. No abstract available.

PMID:
11247299
11.

Systematic genome-wide approach to positional candidate cloning for identification of novel human disease genes.

Kiyosawa H, Kawashima T, Silva D, Petrovsky N, Hasegawa Y, Sakai K, Hayashizaki Y.

Intern Med J. 2004 Mar;34(3):79-90.

PMID:
15030454
12.

Approaches to lipid metabolism gene identification and characterization in the postgenomic era.

Reue K, Vergnes L.

J Lipid Res. 2006 Sep;47(9):1891-907. Epub 2006 Jul 11. Review.

13.

Deductive genomics: a functional approach to identify innovative drug targets in the post-genome era.

Stumm G, Russ A, Nehls M.

Am J Pharmacogenomics. 2002;2(4):263-71. Review.

PMID:
12421097
14.

Genetic dissection of diseases: design and methods.

Hoh J, Ott J.

Curr Opin Genet Dev. 2004 Jun;14(3):229-32. Review.

PMID:
15172663
15.

Pharmacogenetics and disease genetics of complex diseases.

Schmith VD, Campbell DA, Sehgal S, Anderson WH, Burns DK, Middleton LT, Roses AD.

Cell Mol Life Sci. 2003 Aug;60(8):1636-46. Review.

PMID:
14504654
16.

Genomics and medicine. Dissecting human disease in the postgenomic era.

Peltonen L, McKusick VA.

Science. 2001 Feb 16;291(5507):1224-9. No abstract available.

PMID:
11233446
17.

Genes, mutations, and human inherited disease at the dawn of the age of personalized genomics.

Cooper DN, Chen JM, Ball EV, Howells K, Mort M, Phillips AD, Chuzhanova N, Krawczak M, Kehrer-Sawatzki H, Stenson PD.

Hum Mutat. 2010 Jun;31(6):631-55. doi: 10.1002/humu.21260. Review.

PMID:
20506564
18.

Assigning functions to genes--the main challenge of the post-genomics era.

Janitz M.

Rev Physiol Biochem Pharmacol. 2007;159:115-29. Review.

PMID:
17846923
19.

EYE on bioinformatics: dissecting complex disease traits in silico.

Leung YF, Pang CP.

Appl Bioinformatics. 2002;1(2):69-80. Review.

PMID:
15130846
20.

Systematic screens for human disease genes, from yeast to human and back.

Perocchi F, Mancera E, Steinmetz LM.

Mol Biosyst. 2008 Jan;4(1):18-29. Epub 2007 Sep 25. Review.

PMID:
18075670

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