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Voluntary wheel running ameliorates vascular smooth muscle hyper-contractility in type 2 diabetic db/db mice.

Esser KA, Su W, Matveev S, Wong V, Zeng L, McCarthy JJ, Smart EJ, Guo Z, Gong MC.

Appl Physiol Nutr Metab. 2007 Aug;32(4):711-20.


SIRT1 activation ameliorates hyperglycaemia by inducing a torpor-like state in an obese mouse model of type 2 diabetes.

Gilbert RE, Thai K, Advani SL, Cummins CL, Kepecs DM, Schroer SA, Woo M, Zhang Y.

Diabetologia. 2015 Apr;58(4):819-27. doi: 10.1007/s00125-014-3485-4. Epub 2015 Jan 7.


Whole body hyperthermia improves obesity-induced insulin resistance in diabetic mice.

Kokura S, Adachi S, Manabe E, Mizushima K, Hattori T, Okuda T, Nakabe N, Handa O, Takagi T, Naito Y, Yoshida N, Yoshikawa T.

Int J Hyperthermia. 2007 May;23(3):259-65.


Amelioration of long-term renal changes in obese type 2 diabetic mice by a neutralizing vascular endothelial growth factor antibody.

Flyvbjerg A, Dagnaes-Hansen F, De Vriese AS, Schrijvers BF, Tilton RG, Rasch R.

Diabetes. 2002 Oct;51(10):3090-4.


Increase in GLUT1 in smooth muscle alters vascular contractility and increases inflammation in response to vascular injury.

Adhikari N, Basi DL, Carlson M, Mariash A, Hong Z, Lehman U, Mullegama S, Weir EK, Hall JL.

Arterioscler Thromb Vasc Biol. 2011 Jan;31(1):86-94. doi: 10.1161/ATVBAHA.110.215004. Epub 2010 Oct 14.


Effects of insulin resistance on skeletal muscle growth and exercise capacity in type 2 diabetic mouse models.

Ostler JE, Maurya SK, Dials J, Roof SR, Devor ST, Ziolo MT, Periasamy M.

Am J Physiol Endocrinol Metab. 2014 Mar;306(6):E592-605. doi: 10.1152/ajpendo.00277.2013. Epub 2014 Jan 14.


Adiponectin receptor 2 expression in liver and insulin resistance in db/db mice given a beta3-adrenoceptor agonist.

Oana F, Takeda H, Matsuzawa A, Akahane S, Isaji M, Akahane M.

Eur J Pharmacol. 2005 Jul 25;518(1):71-6.


Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice.

Aasum E, Hafstad AD, Severson DL, Larsen TS.

Diabetes. 2003 Feb;52(2):434-41.


Calcium homeostasis in vascular smooth muscle cells is altered in type 2 diabetes by Bcl-2 protein modulation of InsP3R calcium release channels.

Velmurugan GV, White C.

Am J Physiol Heart Circ Physiol. 2012 Jan 1;302(1):H124-34. doi: 10.1152/ajpheart.00218.2011. Epub 2011 Oct 28.


Exercise restores coronary vascular function independent of myogenic tone or hyperglycemic status in db/db mice.

Moien-Afshari F, Ghosh S, Elmi S, Khazaei M, Rahman MM, Sallam N, Laher I.

Am J Physiol Heart Circ Physiol. 2008 Oct;295(4):H1470-80. doi: 10.1152/ajpheart.00016.2008. Epub 2008 Jul 18.


Ezetimibe ameliorates cardiovascular complications and hepatic steatosis in obese and type 2 diabetic db/db mice.

Fukuda M, Nakamura T, Kataoka K, Nako H, Tokutomi Y, Dong YF, Yasuda O, Ogawa H, Kim-Mitsuyama S.

J Pharmacol Exp Ther. 2010 Oct;335(1):70-5. doi: 10.1124/jpet.110.170373. Epub 2010 Jul 22.


Altered clock gene expression and vascular smooth muscle diurnal contractile variations in type 2 diabetic db/db mice.

Su W, Xie Z, Guo Z, Duncan MJ, Lutshumba J, Gong MC.

Am J Physiol Heart Circ Physiol. 2012 Feb 1;302(3):H621-33. doi: 10.1152/ajpheart.00825.2011. Epub 2011 Dec 2.


Structural and functional analysis of pancreatic islets preserved by pioglitazone in db/db mice.

Kawasaki F, Matsuda M, Kanda Y, Inoue H, Kaku K.

Am J Physiol Endocrinol Metab. 2005 Mar;288(3):E510-8. Epub 2004 Nov 2.


Cardiac function and metabolism in Type 2 diabetic mice after treatment with BM 17.0744, a novel PPAR-alpha activator.

Aasum E, Belke DD, Severson DL, Riemersma RA, Cooper M, Andreassen M, Larsen TS.

Am J Physiol Heart Circ Physiol. 2002 Sep;283(3):H949-57.


Effect of curcumin supplementation on blood glucose, plasma insulin, and glucose homeostasis related enzyme activities in diabetic db/db mice.

Seo KI, Choi MS, Jung UJ, Kim HJ, Yeo J, Jeon SM, Lee MK.

Mol Nutr Food Res. 2008 Sep;52(9):995-1004. doi: 10.1002/mnfr.200700184.


Treadmill exercise training fails to reverse defects in glucose, insulin and muscle GLUT4 content in the db/db mouse model of diabetes.

Sennott J, Morrissey J, Standley PR, Broderick TL.

Pathophysiology. 2008 Oct;15(3):173-9. doi: 10.1016/j.pathophys.2008.06.001. Epub 2008 Jul 23.


Wound closure and metabolic parameter variability in a db/db mouse model for diabetic ulcers.

Trousdale RK, Jacobs S, Simhaee DA, Wu JK, Lustbader JW.

J Surg Res. 2009 Jan;151(1):100-7. doi: 10.1016/j.jss.2008.01.023. Epub 2008 Mar 3.


COX-2 up-regulation and vascular smooth muscle contractile hyperreactivity in spontaneous diabetic db/db mice.

Guo Z, Su W, Allen S, Pang H, Daugherty A, Smart E, Gong MC.

Cardiovasc Res. 2005 Sep 1;67(4):723-35.


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