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Items: 1 to 20 of 132

1.

Defining nicotinic agonist binding surfaces through photoaffinity labeling.

Tomizawa M, Maltby D, Medzihradszky KF, Zhang N, Durkin KA, Presley J, Talley TT, Taylor P, Burlingame AL, Casida JE.

Biochemistry. 2007 Jul 31;46(30):8798-806. Epub 2007 Jul 6.

2.

Atypical nicotinic agonist bound conformations conferring subtype selectivity.

Tomizawa M, Maltby D, Talley TT, Durkin KA, Medzihradszky KF, Burlingame AL, Taylor P, Casida JE.

Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1728-32. doi: 10.1073/pnas.0711724105. Epub 2008 Jan 29.

4.

Nicotinic agonist binding site mapped by methionine- and tyrosine-scanning coupled with azidochloropyridinyl photoaffinity labeling.

Tomizawa M, Talley TT, Park JF, Maltby D, Medzihradszky KF, Durkin KA, Cornejo-Bravo JM, Burlingame AL, Casida JE, Taylor P.

J Med Chem. 2009 Jun 25;52(12):3735-41. doi: 10.1021/jm900153c.

5.

alpha-Conotoxin GI benzoylphenylalanine derivatives. (1)H-NMR structures and photoaffinity labeling of the Torpedo californica nicotinic acetylcholine receptor.

Kasheverov IE, Chiara DC, Zhmak MN, Maslennikov IV, Pashkov VS, Arseniev AS, Utkin YN, Cohen JB, Tsetlin VI.

FEBS J. 2006 Apr;273(7):1373-88.

6.

Photoaffinity labeling the agonist binding domain of alpha4beta4 and alpha4beta2 neuronal nicotinic acetylcholine receptors with [(125)I]epibatidine and 5[(125)I]A-85380.

Hamouda AK, Jin X, Sanghvi M, Srivastava S, Pandhare A, Duddempudi PK, Steinbach JH, Blanton MP.

Biochim Biophys Acta. 2009 Sep;1788(9):1987-95. doi: 10.1016/j.bbamem.2009.06.012. Epub 2009 Jun 21.

8.

Molecular recognition of neonicotinoid insecticides: the determinants of life or death.

Tomizawa M, Casida JE.

Acc Chem Res. 2009 Feb 17;42(2):260-9. doi: 10.1021/ar800131p. Review.

PMID:
19053239
9.
10.

Structural and functional studies of the modulator NS9283 reveal agonist-like mechanism of action at α4β2 nicotinic acetylcholine receptors.

Olsen JA, Ahring PK, Kastrup JS, Gajhede M, Balle T.

J Biol Chem. 2014 Sep 5;289(36):24911-21. doi: 10.1074/jbc.M114.568097. Epub 2014 Jun 30.

11.

Mapping the elusive neonicotinoid binding site.

Tomizawa M, Talley TT, Maltby D, Durkin KA, Medzihradszky KF, Burlingame AL, Taylor P, Casida JE.

Proc Natl Acad Sci U S A. 2007 May 22;104(21):9075-80. Epub 2007 May 7.

12.

Differential α4(+)/(-)β2 Agonist-binding Site Contributions to α4β2 Nicotinic Acetylcholine Receptor Function within and between Isoforms.

Lucero LM, Weltzin MM, Eaton JB, Cooper JF, Lindstrom JM, Lukas RJ, Whiteaker P.

J Biol Chem. 2016 Jan 29;291(5):2444-59. doi: 10.1074/jbc.M115.684373. Epub 2015 Dec 7.

14.

Synthesis and pharmacological characterization of novel analogues of the nicotinic acetylcholine receptor agonist (+/-)-UB-165.

Sharples CG, Karig G, Simpson GL, Spencer JA, Wright E, Millar NS, Wonnacott S, Gallagher T.

J Med Chem. 2002 Jul 18;45(15):3235-45.

PMID:
12109907
15.

Complex between α-bungarotoxin and an α7 nicotinic receptor ligand-binding domain chimaera.

Huang S, Li SX, Bren N, Cheng K, Gomoto R, Chen L, Sine SM.

Biochem J. 2013 Sep 1;454(2):303-10. doi: 10.1042/BJ20130636.

16.

Photoaffinity labeling of nicotinic receptors: diversity of drug binding sites!

Hamouda AK, Jayakar SS, Chiara DC, Cohen JB.

J Mol Neurosci. 2014 Jul;53(3):480-6. doi: 10.1007/s12031-013-0150-1. Epub 2013 Oct 26. Review.

PMID:
24158732
17.

Role in the selectivity of neonicotinoids of insect-specific basic residues in loop D of the nicotinic acetylcholine receptor agonist binding site.

Shimomura M, Yokota M, Ihara M, Akamatsu M, Sattelle DB, Matsuda K.

Mol Pharmacol. 2006 Oct;70(4):1255-63. Epub 2006 Jul 25.

18.

Identifying barbiturate binding sites in a nicotinic acetylcholine receptor with [3H]allyl m-trifluoromethyldiazirine mephobarbital, a photoreactive barbiturate.

Hamouda AK, Stewart DS, Chiara DC, Savechenkov PY, Bruzik KS, Cohen JB.

Mol Pharmacol. 2014 May;85(5):735-46. doi: 10.1124/mol.113.090985. Epub 2014 Feb 21.

19.

[3H]Benzophenone photolabeling identifies state-dependent changes in nicotinic acetylcholine receptor structure.

Garcia G 3rd, Chiara DC, Nirthanan S, Hamouda AK, Stewart DS, Cohen JB.

Biochemistry. 2007 Sep 11;46(36):10296-307. Epub 2007 Aug 9.

PMID:
17685589
20.

Identification of nicotinic acetylcholine receptor amino acids photolabeled by the volatile anesthetic halothane.

Chiara DC, Dangott LJ, Eckenhoff RG, Cohen JB.

Biochemistry. 2003 Nov 25;42(46):13457-67.

PMID:
14621991

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