Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 57

1.

Over-expression of amyloid precursor protein in HEK cells alters p53 conformational state and protects against doxorubicin.

Uberti D, Cenini G, Olivari L, Ferrari-Toninelli G, Porrello E, Cecchi C, Pensalfini A, Liguri G, Govoni S, Racchi M, Maurizio M.

J Neurochem. 2007 Oct;103(1):322-33. Epub 2007 Jul 2. Erratum in: J Neurochem. 2008 Mar; 104(5) 1430. Pensafini, Anna [corrected to Pensalfini, Anna].

2.

Reduced retinal function in amyloid precursor protein-over-expressing transgenic mice via attenuating glutamate-N-methyl-d-aspartate receptor signaling.

Shimazawa M, Inokuchi Y, Okuno T, Nakajima Y, Sakaguchi G, Kato A, Oku H, Sugiyama T, Kudo T, Ikeda T, Takeda M, Hara H.

J Neurochem. 2008 Oct;107(1):279-90. doi: 10.1111/j.1471-4159.2008.05606.x. Epub 2008 Aug 7.

3.

Vascular endothelial growth factor (VEGF) affects processing of amyloid precursor protein and beta-amyloidogenesis in brain slice cultures derived from transgenic Tg2576 mouse brain.

Bürger S, Noack M, Kirazov LP, Kirazov EP, Naydenov CL, Kouznetsova E, Yafai Y, Schliebs R.

Int J Dev Neurosci. 2009 Oct;27(6):517-23. doi: 10.1016/j.ijdevneu.2009.06.011. Epub 2009 Jul 7.

PMID:
19589380
4.

Effect of amyloid beta on capacitive calcium entry in neural 2a cells.

Niu Y, Su Z, Zhao C, Song B, Zhang X, Zhao N, Shen X, Gong Y.

Brain Res Bull. 2009 Mar 16;78(4-5):152-7. doi: 10.1016/j.brainresbull.2008.10.003. Epub 2008 Nov 8.

PMID:
19000747
5.

Abeta(1-40)-induced secretion of matrix metalloproteinase-9 results in sAPPalpha release by association with cell surface APP.

Talamagas AA, Efthimiopoulos S, Tsilibary EC, Figueiredo-Pereira ME, Tzinia AK.

Neurobiol Dis. 2007 Dec;28(3):304-15. Epub 2007 Jul 24.

PMID:
17761425
6.

Dynamics of Abeta turnover and deposition in different beta-amyloid precursor protein transgenic mouse models following gamma-secretase inhibition.

Abramowski D, Wiederhold KH, Furrer U, Jaton AL, Neuenschwander A, Runser MJ, Danner S, Reichwald J, Ammaturo D, Staab D, Stoeckli M, Rueeger H, Neumann U, Staufenbiel M.

J Pharmacol Exp Ther. 2008 Nov;327(2):411-24. doi: 10.1124/jpet.108.140327. Epub 2008 Aug 7.

7.

Involvement of prostaglandin E2 in production of amyloid-beta peptides both in vitro and in vivo.

Hoshino T, Nakaya T, Homan T, Tanaka K, Sugimoto Y, Araki W, Narita M, Narumiya S, Suzuki T, Mizushima T.

J Biol Chem. 2007 Nov 9;282(45):32676-88. Epub 2007 Sep 2.

8.

Fibrillar prion peptide PrP(106-126) treatment induces Dab1 phosphorylation and impairs APP processing and Abeta production in cortical neurons.

Gavín R, Ureña J, Rangel A, Pastrana MA, Requena JR, Soriano E, Aguzzi A, Del Río JA.

Neurobiol Dis. 2008 May;30(2):243-54. doi: 10.1016/j.nbd.2008.02.001. Epub 2008 Feb 16.

PMID:
18374587
9.

Selective modulation of amyloid-beta peptide degradation by flurbiprofen, fenofibrate, and related compounds regulates Abeta levels.

Abdul-Hay SO, Edirisinghe P, Thatcher GR.

J Neurochem. 2009 Nov;111(3):683-95. doi: 10.1111/j.1471-4159.2009.06355.x. Epub 2009 Aug 22.

10.

NFkappaB-dependent control of BACE1 promoter transactivation by Abeta42.

Buggia-Prevot V, Sevalle J, Rossner S, Checler F.

J Biol Chem. 2008 Apr 11;283(15):10037-47. doi: 10.1074/jbc.M706579200. Epub 2008 Feb 8.

11.

Intracellular copper deficiency increases amyloid-beta secretion by diverse mechanisms.

Cater MA, McInnes KT, Li QX, Volitakis I, La Fontaine S, Mercer JF, Bush AI.

Biochem J. 2008 May 15;412(1):141-52. doi: 10.1042/BJ20080103.

PMID:
18248325
12.

P-glycoprotein efflux and other factors limit brain amyloid beta reduction by beta-site amyloid precursor protein-cleaving enzyme 1 inhibitors in mice.

Meredith JE Jr, Thompson LA, Toyn JH, Marcin L, Barten DM, Marcinkeviciene J, Kopcho L, Kim Y, Lin A, Guss V, Burton C, Iben L, Polson C, Cantone J, Ford M, Drexler D, Fiedler T, Lentz KA, Grace JE Jr, Kolb J, Corsa J, Pierdomenico M, Jones K, Olson RE, Macor JE, Albright CF.

J Pharmacol Exp Ther. 2008 Aug;326(2):502-13. doi: 10.1124/jpet.108.138974. Epub 2008 May 22.

13.
14.

Inhibition of gamma-secretase activity reduces Abeta production, reduces oxidative stress, increases mitochondrial activity and leads to reduced vulnerability to apoptosis: Implications for the treatment of Alzheimer's disease.

Sheng B, Gong K, Niu Y, Liu L, Yan Y, Lu G, Zhang L, Hu M, Zhao N, Zhang X, Tang P, Gong Y.

Free Radic Biol Med. 2009 May 15;46(10):1362-75. doi: 10.1016/j.freeradbiomed.2009.02.018. Epub 2009 Mar 3.

PMID:
19264123
15.

Rac1 inhibition negatively regulates transcriptional activity of the amyloid precursor protein gene.

Wang PL, Niidome T, Akaike A, Kihara T, Sugimoto H.

J Neurosci Res. 2009 Jul;87(9):2105-14. doi: 10.1002/jnr.22039.

PMID:
19267423
16.

Begacestat (GSI-953): a novel, selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase for the treatment of Alzheimer's disease.

Martone RL, Zhou H, Atchison K, Comery T, Xu JZ, Huang X, Gong X, Jin M, Kreft A, Harrison B, Mayer SC, Aschmies S, Gonzales C, Zaleska MM, Riddell DR, Wagner E, Lu P, Sun SC, Sonnenberg-Reines J, Oganesian A, Adkins K, Leach MW, Clarke DW, Huryn D, Abou-Gharbia M, Magolda R, Bard J, Frick G, Raje S, Forlow SB, Balliet C, Burczynski ME, Reinhart PH, Wan HI, Pangalos MN, Jacobsen JS.

J Pharmacol Exp Ther. 2009 Nov;331(2):598-608. doi: 10.1124/jpet.109.152975. Epub 2009 Aug 11.

17.

A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein.

Schöbel S, Neumann S, Hertweck M, Dislich B, Kuhn PH, Kremmer E, Seed B, Baumeister R, Haass C, Lichtenthaler SF.

J Biol Chem. 2008 May 23;283(21):14257-68. doi: 10.1074/jbc.M801531200. Epub 2008 Mar 19.

18.

CD40/CD40L interaction induces Abeta production and increases gamma-secretase activity independently of tumor necrosis factor receptor associated factor (TRAF) signaling.

Volmar CH, Ait-Ghezala G, Frieling J, Weeks OI, Mullan MJ.

Exp Cell Res. 2009 Aug 1;315(13):2265-74. doi: 10.1016/j.yexcr.2009.04.023. Epub 2009 May 5.

PMID:
19422822
19.

Aminopeptidase A contributes to the N-terminal truncation of amyloid beta-peptide.

Sevalle J, Amoyel A, Robert P, Fournié-Zaluski MC, Roques B, Checler F.

J Neurochem. 2009 Apr;109(1):248-56. doi: 10.1111/j.1471-4159.2009.05950.x. Epub 2009 Feb 23.

20.

IGF-1 promotes beta-amyloid production by a secretase-independent mechanism.

Araki W, Kume H, Oda A, Tamaoka A, Kametani F.

Biochem Biophys Res Commun. 2009 Feb 27;380(1):111-4. doi: 10.1016/j.bbrc.2009.01.044. Epub 2009 Jan 22.

PMID:
19167357

Supplemental Content

Support Center