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Items: 1 to 20 of 86

1.

Modification of the ceramide moiety of isoglobotrihexosylceramide on its agonist activity in stimulation of invariant natural killer T cells.

Xia C, Schümann J, Emmanuel R, Zhang Y, Chen W, Zhang W, De Libero G, Wang PG.

J Med Chem. 2007 Jul 26;50(15):3489-96. Epub 2007 Jul 4.

PMID:
17608465
2.

Synthesis and structure-activity relationship study of isoglobotrihexosylceramide analogues.

Chen W, Xia C, Wang J, Thapa P, Li Y, Talukdar A, Nadas J, Zhang W, Zhou D, Wang PG.

J Org Chem. 2007 Dec 21;72(26):9914-23. Epub 2007 Nov 17. Erratum in: J Org Chem. 2008 Jun 20;73(12):4762. Talukdar, Arindam [added].

PMID:
18020363
3.

Thio-isoglobotrihexosylceramide, an agonist for activating invariant natural killer T cells.

Xia C, Zhou D, Liu C, Lou Y, Yao Q, Zhang W, Wang PG.

Org Lett. 2006 Nov 23;8(24):5493-6.

PMID:
17107055
4.

Chemical modification of iGb3 increases IFN-gamma production by hepatic NKT cells.

Shang P, Zhang C, Xia C, Chen W, Han Q, Wang PG, Zhang J, Tian Z.

Int Immunopharmacol. 2008 May;8(5):645-53. doi: 10.1016/j.intimp.2008.01.003. Epub 2008 Feb 12.

PMID:
18387506
5.

Enhanced antitumor effects by chemical modified IGb3 analogues.

Zhou Z, Zhang C, Xia C, Chen W, Zhu H, Shang P, Ma F, Wang PG, Zhang J, Xu W, Tian Z.

Mol Cancer Ther. 2011 Aug;10(8):1375-84. doi: 10.1158/1535-7163.MCT-11-0030. Epub 2011 Jun 8.

6.

Synthesis and biological evaluation of alpha-galactosylceramide (KRN7000) and isoglobotrihexosylceramide (iGb3).

Xia C, Yao Q, Schümann J, Rossy E, Chen W, Zhu L, Zhang W, De Libero G, Wang PG.

Bioorg Med Chem Lett. 2006 Apr 15;16(8):2195-9. Epub 2006 Feb 2.

PMID:
16458002
7.

Alpha anomers of iGb3 and Gb3 stimulate cytokine production by natural killer T cells.

Yin N, Long X, Goff RD, Zhou D, Cantu C 3rd, Mattner J, Mezard PS, Teyton L, Bendelac A, Savage PB.

ACS Chem Biol. 2009 Mar 20;4(3):199-208. doi: 10.1021/cb800277n.

8.

A divergent approach to the synthesis of iGb3 sugar and lipid analogues via a lactosyl 2-azido-sphingosine intermediate.

Cheng JM, Dangerfield EM, Timmer MS, Stocker BL.

Org Biomol Chem. 2014 May 7;12(17):2729-36. doi: 10.1039/c4ob00241e.

PMID:
24652424
9.

CD1d protein structure determines species-selective antigenicity of isoglobotrihexosylceramide (iGb3) to invariant NKT cells.

Sanderson JP, Brennan PJ, Mansour S, Matulis G, Patel O, Lissin N, Godfrey DI, Kawahara K, Zähringer U, Rossjohn J, Brenner MB, Gadola SD.

Eur J Immunol. 2013 Mar;43(3):815-25. doi: 10.1002/eji.201242952. Epub 2013 Jan 31.

10.

Efficient activation of Valpha14 invariant NKT cells by foreign lipid antigen is associated with concurrent dendritic cell-specific self recognition.

Cheng L, Ueno A, Cho S, Im JS, Golby S, Hou S, Porcelli SA, Yang Y.

J Immunol. 2007 Mar 1;178(5):2755-62.

11.

Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency.

Porubsky S, Speak AO, Luckow B, Cerundolo V, Platt FM, Gröne HJ.

Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):5977-82. Epub 2007 Mar 19.

12.

Crystal structures of mouse CD1d-iGb3 complex and its cognate Valpha14 T cell receptor suggest a model for dual recognition of foreign and self glycolipids.

Zajonc DM, Savage PB, Bendelac A, Wilson IA, Teyton L.

J Mol Biol. 2008 Apr 4;377(4):1104-16. doi: 10.1016/j.jmb.2008.01.061. Epub 2008 Jan 31.

13.

CD4 engagement by CD1d potentiates activation of CD4+ invariant NKT cells.

Thedrez A, de Lalla C, Allain S, Zaccagnino L, Sidobre S, Garavaglia C, Borsellino G, Dellabona P, Bonneville M, Scotet E, Casorati G.

Blood. 2007 Jul 1;110(1):251-8. Epub 2007 Mar 15.

14.

Uncoupling between CD1d upregulation induced by retinoic acid and conduritol-B-epoxide and iNKT cell responsiveness.

Balreira A, Cavallari M, Sá Miranda MC, Arosa FA.

Immunobiology. 2010 Jun;215(6):505-13. doi: 10.1016/j.imbio.2009.07.002. Epub 2009 Aug 3.

PMID:
19651460
15.

IFN-gamma-producing human invariant NKT cells promote tumor-associated antigen-specific cytotoxic T cell responses.

Moreno M, Molling JW, von Mensdorff-Pouilly S, Verheijen RH, Hooijberg E, Kramer D, Reurs AW, van den Eertwegh AJ, von Blomberg BM, Scheper RJ, Bontkes HJ.

J Immunol. 2008 Aug 15;181(4):2446-54.

16.

Human invariant NKT cells display alloreactivity instructed by invariant TCR-CD1d interaction and killer Ig receptors.

Patterson S, Chaidos A, Neville DC, Poggi A, Butters TD, Roberts IA, Karadimitris A.

J Immunol. 2008 Sep 1;181(5):3268-76.

17.

Chemoenzymatic syntheses of iGb3 and Gb3.

Yao Q, Song J, Xia C, Zhang W, Wang PG.

Org Lett. 2006 Mar 2;8(5):911-4.

PMID:
16494472
18.

Aging is associated with a rapid decline in frequency, alterations in subset composition, and enhanced Th2 response in CD1d-restricted NKT cells from human peripheral blood.

Jing Y, Gravenstein S, Chaganty NR, Chen N, Lyerly KH, Joyce S, Deng Y.

Exp Gerontol. 2007 Aug;42(8):719-32. Epub 2007 Feb 6.

PMID:
17368996
19.

Lysosomal glycosphingolipid recognition by NKT cells.

Zhou D, Mattner J, Cantu C 3rd, Schrantz N, Yin N, Gao Y, Sagiv Y, Hudspeth K, Wu YP, Yamashita T, Teneberg S, Wang D, Proia RL, Levery SB, Savage PB, Teyton L, Bendelac A.

Science. 2004 Dec 3;306(5702):1786-9. Epub 2004 Nov 11.

20.

Sensitive quantitation of isoglobotriaosylceramide in the presence of isobaric components using electrospray ionization-ion trap mass spectrometry.

Li Y, Zhou D, Xia C, Wang PG, Levery SB.

Glycobiology. 2008 Feb;18(2):166-76. Epub 2007 Nov 28.

PMID:
18048405

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