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Items: 1 to 20 of 64

1.

CCN6 (WISP3) as a new regulator of the epithelial phenotype in breast cancer.

Kleer CG, Zhang Y, Merajver SD.

Cells Tissues Organs. 2007;185(1-3):95-9. Review.

PMID:
17587813
2.

Rb depletion results in deregulation of E-cadherin and induction of cellular phenotypic changes that are characteristic of the epithelial-to-mesenchymal transition.

Arima Y, Inoue Y, Shibata T, Hayashi H, Nagano O, Saya H, Taya Y.

Cancer Res. 2008 Jul 1;68(13):5104-12. doi: 10.1158/0008-5472.CAN-07-5680.

3.

Inhibition of CCN6 (Wnt-1-induced signaling protein 3) down-regulates E-cadherin in the breast epithelium through induction of snail and ZEB1.

Huang W, Zhang Y, Varambally S, Chinnaiyan AM, Banerjee M, Merajver SD, Kleer CG.

Am J Pathol. 2008 Apr;172(4):893-904. doi: 10.2353/ajpath.2008.070899. Epub 2008 Mar 5.

4.
5.

A novel putative low-affinity insulin-like growth factor-binding protein, LIBC (lost in inflammatory breast cancer), and RhoC GTPase correlate with the inflammatory breast cancer phenotype.

van Golen KL, Davies S, Wu ZF, Wang Y, Bucana CD, Root H, Chandrasekharappa S, Strawderman M, Ethier SP, Merajver SD.

Clin Cancer Res. 1999 Sep;5(9):2511-9.

6.

CCN6 (WISP3) decreases ZEB1-mediated EMT and invasion by attenuation of IGF-1 receptor signaling in breast cancer.

Lorenzatti G, Huang W, Pal A, Cabanillas AM, Kleer CG.

J Cell Sci. 2011 May 15;124(Pt 10):1752-8. doi: 10.1242/jcs.084194. Epub 2011 Apr 26.

7.

Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype.

SarriĆ³ D, Rodriguez-Pinilla SM, Hardisson D, Cano A, Moreno-Bueno G, Palacios J.

Cancer Res. 2008 Feb 15;68(4):989-97. doi: 10.1158/0008-5472.CAN-07-2017.

8.
9.

Overexpression of endoplasmic reticulum protein 29 regulates mesenchymal-epithelial transition and suppresses xenograft tumor growth of invasive breast cancer cells.

Bambang IF, Xu S, Zhou J, Salto-Tellez M, Sethi SK, Zhang D.

Lab Invest. 2009 Nov;89(11):1229-42. doi: 10.1038/labinvest.2009.87. Epub 2009 Sep 21.

10.

The matricellular protein CCN6 (WISP3) decreases Notch1 and suppresses breast cancer initiating cells.

Huang W, Martin EE, Burman B, Gonzalez ME, Kleer CG.

Oncotarget. 2016 May 3;7(18):25180-93. doi: 10.18632/oncotarget.7734.

11.

Blockade of CCN6 (WISP3) activates growth factor-independent survival and resistance to anoikis in human mammary epithelial cells.

Huang W, Gonzalez ME, Toy KA, Banerjee M, Kleer CG.

Cancer Res. 2010 Apr 15;70(8):3340-50. doi: 10.1158/0008-5472.CAN-09-4225.

12.
13.

Vimentin and epithelial-mesenchymal transition in human breast cancer--observations in vitro and in vivo.

Kokkinos MI, Wafai R, Wong MK, Newgreen DF, Thompson EW, Waltham M.

Cells Tissues Organs. 2007;185(1-3):191-203. Review.

PMID:
17587825
15.

CCN6 enhances ICAM-1 expression and cell motility in human chondrosarcoma cells.

Fong YC, Lin CY, Su YC, Chen WC, Tsai FJ, Tsai CH, Huang CY, Tang CH.

J Cell Physiol. 2012 Jan;227(1):223-32. doi: 10.1002/jcp.22720.

PMID:
21391218
16.

Role of CCN, a vertebrate specific gene family, in development.

Katsube K, Sakamoto K, Tamamura Y, Yamaguchi A.

Dev Growth Differ. 2009 Jan;51(1):55-67. doi: 10.1111/j.1440-169X.2009.01077.x. Review.

PMID:
19128405
17.

Inhibition of SHP2 leads to mesenchymal to epithelial transition in breast cancer cells.

Zhou XD, Agazie YM.

Cell Death Differ. 2008 Jun;15(6):988-96. doi: 10.1038/cdd.2008.54. Epub 2008 Apr 18.

18.

BMP-7 fails to attenuate TGF-beta1-induced epithelial-to-mesenchymal transition in human proximal tubule epithelial cells.

Dudas PL, Argentieri RL, Farrell FX.

Nephrol Dial Transplant. 2009 May;24(5):1406-16. doi: 10.1093/ndt/gfn662. Epub 2008 Dec 4.

PMID:
19056781
19.

MMTV-cre;Ccn6 knockout mice develop tumors recapitulating human metaplastic breast carcinomas.

Martin EE, Huang W, Anwar T, Arellano-Garcia C, Burman B, Guan JL, Gonzalez ME, Kleer CG.

Oncogene. 2017 Apr 20;36(16):2275-2285. doi: 10.1038/onc.2016.381. Epub 2016 Nov 7.

20.

Matricellular CCN6 (WISP3) protein: a tumor suppressor for mammary metaplastic carcinomas.

Tran MN, Kleer CG.

J Cell Commun Signal. 2018 Jan 22. doi: 10.1007/s12079-018-0451-9. [Epub ahead of print] Review.

PMID:
29357008

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