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Items: 1 to 20 of 163


The contribution of organic anion transporters OAT1 and OAT3 to the renal uptake of rosuvastatin.

Windass AS, Lowes S, Wang Y, Brown CD.

J Pharmacol Exp Ther. 2007 Sep;322(3):1221-7. Epub 2007 Jun 21.


Characterization of uremic toxin transport by organic anion transporters in the kidney.

Deguchi T, Kusuhara H, Takadate A, Endou H, Otagiri M, Sugiyama Y.

Kidney Int. 2004 Jan;65(1):162-74.


Characterization of the uptake of organic anion transporter (OAT) 1 and OAT3 substrates by human kidney slices.

Nozaki Y, Kusuhara H, Kondo T, Hasegawa M, Shiroyanagi Y, Nakazawa H, Okano T, Sugiyama Y.

J Pharmacol Exp Ther. 2007 Apr;321(1):362-9. Epub 2007 Jan 25.


Transport of xanthurenic acid by rat/human organic anion transporters OAT1 and OAT3.

Uwai Y, Honjo E.

Biosci Biotechnol Biochem. 2013;77(7):1517-21. Epub 2013 Jul 7.


Evaluation of a potential transporter-mediated drug interaction between rosuvastatin and pradigastat, a novel DGAT-1 inhibitor.

Kulmatycki K, Hanna I, Meyers D, Salunke A, Movva A, Majumdar T, Natrillo A, Vapurcuyan A, Rebello S, Sunkara G, Chen J.

Int J Clin Pharmacol Ther. 2015 May;53(5):345-55. doi: 10.5414/CP202275.


Expression and function of Oat1 and Oat3 in rat kidney exposed to mercuric chloride.

Di Giusto G, Anzai N, Ruiz ML, Endou H, Torres AM.

Arch Toxicol. 2009 Oct;83(10):887-97. doi: 10.1007/s00204-009-0445-8. Epub 2009 Jun 17.


A role for the organic anion transporter OAT3 in renal creatinine secretion in mice.

Vallon V, Eraly SA, Rao SR, Gerasimova M, Rose M, Nagle M, Anzai N, Smith T, Sharma K, Nigam SK, Rieg T.

Am J Physiol Renal Physiol. 2012 May 15;302(10):F1293-9. doi: 10.1152/ajprenal.00013.2012. Epub 2012 Feb 15.


Downregulation of organic anion transporters OAT1 and OAT3 correlates with impaired secretion of para-aminohippurate after ischemic acute renal failure in rats.

Schneider R, Sauvant C, Betz B, Otremba M, Fischer D, Holzinger H, Wanner C, Galle J, Gekle M.

Am J Physiol Renal Physiol. 2007 May;292(5):F1599-605. Epub 2007 Jan 23.


Differential Interaction of Dantrolene, Glafenine, Nalidixic Acid, and Prazosin with Human Organic Anion Transporters 1 and 3.

Burckhardt BC, Henjakovic M, Hagos Y, Burckhardt G.

J Pharmacol Exp Ther. 2017 Sep;362(3):450-458. doi: 10.1124/jpet.117.241406. Epub 2017 Jun 19.


Regulation of renal organic anion transporter 3 (SLC22A8) expression and function by the integrity of lipid raft domains and their associated cytoskeleton.

Srimaroeng C, Cecile JP, Walden R, Pritchard JB.

Cell Physiol Biochem. 2013;31(4-5):565-78. doi: 10.1159/000350077. Epub 2013 Apr 26.


Organic anion transporters involved in the excretion of bestatin in the kidney.

Zhu Y, Meng Q, Wang C, Liu Q, Sun H, Kaku T, Liu K.

Peptides. 2012 Feb;33(2):265-71. doi: 10.1016/j.peptides.2012.01.007. Epub 2012 Jan 18.


Inhibitory effect of selective cyclooxygenase-2 inhibitor lumiracoxib on human organic anion transporters hOAT1 and hOAT3.

Uwai Y, Honjo H, Iwamoto K.

Drug Metab Pharmacokinet. 2010;25(5):450-5. Epub 2010 Sep 22.


The flounder organic anion transporter fOat has sequence, function, and substrate specificity similarity to both mammalian Oat1 and Oat3.

Aslamkhan AG, Thompson DM, Perry JL, Bleasby K, Wolff NA, Barros S, Miller DS, Pritchard JB.

Am J Physiol Regul Integr Comp Physiol. 2006 Dec;291(6):R1773-80. Epub 2006 Jul 20.


Human organic anion transporters 1 (hOAT1/SLC22A6) and 3 (hOAT3/SLC22A8) transport edaravone (MCI-186; 3-methyl-1-phenyl-2-pyrazolin-5-one) and its sulfate conjugate.

Mizuno N, Takahashi T, Iwase Y, Kusuhara H, Niwa T, Sugiyama Y.

Drug Metab Dispos. 2007 Aug;35(8):1429-34. Epub 2007 May 14.


Mycophenolic acid (MPA) and its glucuronide metabolites interact with transport systems responsible for excretion of organic anions in the basolateral membrane of the human kidney.

Wolff NA, Burckhardt BC, Burckhardt G, Oellerich M, Armstrong VW.

Nephrol Dial Transplant. 2007 Sep;22(9):2497-503. Epub 2007 May 25.


Transport of the natural sweetener stevioside and its aglycone steviol by human organic anion transporter (hOAT1; SLC22A6) and hOAT3 (SLC22A8).

Srimaroeng C, Chatsudthipong V, Aslamkhan AG, Pritchard JB.

J Pharmacol Exp Ther. 2005 May;313(2):621-8. Epub 2005 Jan 11.


Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na+ gradient.

Sweet DH, Chan LM, Walden R, Yang XP, Miller DS, Pritchard JB.

Am J Physiol Renal Physiol. 2003 Apr;284(4):F763-9. Epub 2002 Dec 17.


Inhibitory effect of JBP485 on renal excretion of acyclovir by the inhibition of OAT1 and OAT3.

Ye J, Liu Q, Wang C, Meng Q, Peng J, Sun H, Kaku T, Liu K.

Eur J Pharm Sci. 2012 Sep 29;47(2):341-6. doi: 10.1016/j.ejps.2012.06.004. Epub 2012 Jun 21.


Renal uptake of substrates for organic anion transporters Oat1 and Oat3 and organic cation transporters Oct1 and Oct2 is altered in rats with adenine-induced chronic renal failure.

Komazawa H, Yamaguchi H, Hidaka K, Ogura J, Kobayashi M, Iseki K.

J Pharm Sci. 2013 Mar;102(3):1086-94. doi: 10.1002/jps.23433. Epub 2012 Dec 29.


Relative contribution of OAT and OCT transporters to organic electrolyte transport in rabbit proximal tubule.

Zhang X, Groves CE, Bahn A, Barendt WM, Prado MD, Rödiger M, Chatsudthipong V, Burckhardt G, Wright SH.

Am J Physiol Renal Physiol. 2004 Nov;287(5):F999-1010. Epub 2004 Jul 13.


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