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Items: 1 to 20 of 298

1.

Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitination.

Tang X, Orlicky S, Lin Z, Willems A, Neculai D, Ceccarelli D, Mercurio F, Shilton BH, Sicheri F, Tyers M.

Cell. 2007 Jun 15;129(6):1165-76.

2.

A refined two-hybrid system reveals that SCF(Cdc4)-dependent degradation of Swi5 contributes to the regulatory mechanism of S-phase entry.

Kishi T, Ikeda A, Koyama N, Fukada J, Nagao R.

Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14497-502. doi: 10.1073/pnas.0806253105. Epub 2008 Sep 11.

3.

Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase.

Orlicky S, Tang X, Willems A, Tyers M, Sicheri F.

Cell. 2003 Jan 24;112(2):243-56.

4.

Transferable domain in the G(1) cyclin Cln2 sufficient to switch degradation of Sic1 from the E3 ubiquitin ligase SCF(Cdc4) to SCF(Grr1).

Berset C, Griac P, Tempel R, La Rue J, Wittenberg C, Lanker S.

Mol Cell Biol. 2002 Jul;22(13):4463-76.

6.

Release of ubiquitin-charged Cdc34-S - Ub from the RING domain is essential for ubiquitination of the SCF(Cdc4)-bound substrate Sic1.

Deffenbaugh AE, Scaglione KM, Zhang L, Moore JM, Buranda T, Sklar LA, Skowyra D.

Cell. 2003 Sep 5;114(5):611-22.

7.

SCF ubiquitin protein ligases and phosphorylation-dependent proteolysis.

Willems AR, Goh T, Taylor L, Chernushevich I, Shevchenko A, Tyers M.

Philos Trans R Soc Lond B Biol Sci. 1999 Sep 29;354(1389):1533-50.

8.

Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases.

Hao B, Oehlmann S, Sowa ME, Harper JW, Pavletich NP.

Mol Cell. 2007 Apr 13;26(1):131-43.

9.

Genome-wide surveys for phosphorylation-dependent substrates of SCF ubiquitin ligases.

Tang X, Orlicky S, Liu Q, Willems A, Sicheri F, Tyers M.

Methods Enzymol. 2005;399:433-58.

PMID:
16338374
10.

Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication.

Nash P, Tang X, Orlicky S, Chen Q, Gertler FB, Mendenhall MD, Sicheri F, Pawson T, Tyers M.

Nature. 2001 Nov 29;414(6863):514-21.

PMID:
11734846
11.
12.

In vitro reconstitution of SCF substrate ubiquitination with purified proteins.

Petroski MD, Deshaies RJ.

Methods Enzymol. 2005;398:143-58.

PMID:
16275326
13.

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex.

Skowyra D, Craig KL, Tyers M, Elledge SJ, Harper JW.

Cell. 1997 Oct 17;91(2):209-19.

14.

Functional interaction of 13 yeast SCF complexes with a set of yeast E2 enzymes in vitro.

Kus BM, Caldon CE, Andorn-Broza R, Edwards AM.

Proteins. 2004 Feb 15;54(3):455-67.

PMID:
14747994
15.

Structural basis for the selection of glycosylated substrates by SCF(Fbs1) ubiquitin ligase.

Mizushima T, Yoshida Y, Kumanomidou T, Hasegawa Y, Suzuki A, Yamane T, Tanaka K.

Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):5777-81. Epub 2007 Mar 26.

16.

Unique role for the UbL-UbA protein Ddi1 in turnover of SCFUfo1 complexes.

Ivantsiv Y, Kaplun L, Tzirkin-Goldin R, Shabek N, Raveh D.

Mol Cell Biol. 2006 Mar;26(5):1579-88.

17.

The ubiquitin ligase SCF(Grr1) is required for Gal2p degradation in the yeast Saccharomyces cerevisiae.

Horak J, Wolf DH.

Biochem Biophys Res Commun. 2005 Oct 7;335(4):1185-90.

PMID:
16112084
18.

M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP.

Watanabe N, Arai H, Nishihara Y, Taniguchi M, Watanabe N, Hunter T, Osada H.

Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4419-24. Epub 2004 Mar 22.

19.

Identification of residues in the WD-40 repeat motif of the F-box protein Met30p required for interaction with its substrate Met4p.

Brunson LE, Dixon C, LeFebvre A, Sun L, Mathias N.

Mol Genet Genomics. 2005 Jun;273(5):361-70. Epub 2005 May 10.

PMID:
15883825
20.

Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34.

Seol JH, Feldman RM, Zachariae W, Shevchenko A, Correll CC, Lyapina S, Chi Y, Galova M, Claypool J, Sandmeyer S, Nasmyth K, Deshaies RJ, Shevchenko A, Deshaies RJ.

Genes Dev. 1999 Jun 15;13(12):1614-26.

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