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Items: 1 to 20 of 182


Efficient Tor signaling requires a functional class C Vps protein complex in Saccharomyces cerevisiae.

Zurita-Martinez SA, Puria R, Pan X, Boeke JD, Cardenas ME.

Genetics. 2007 Aug;176(4):2139-50.


Endolysosomal membrane trafficking complexes drive nutrient-dependent TORC1 signaling to control cell growth in Saccharomyces cerevisiae.

Kingsbury JM, Sen ND, Maeda T, Heitman J, Cardenas ME.

Genetics. 2014 Apr;196(4):1077-89. doi: 10.1534/genetics.114.161646.


TOR1 and TOR2 have distinct locations in live cells.

Sturgill TW, Cohen A, Diefenbacher M, Trautwein M, Martin DE, Hall MN.

Eukaryot Cell. 2008 Oct;7(10):1819-30. doi: 10.1128/EC.00088-08.


TORC2 signaling is antagonized by protein phosphatase 2A and the Far complex in Saccharomyces cerevisiae.

Pracheil T, Thornton J, Liu Z.

Genetics. 2012 Apr;190(4):1325-39. doi: 10.1534/genetics.111.138305.


Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method.

Xie MW, Jin F, Hwang H, Hwang S, Anand V, Duncan MC, Huang J.

Proc Natl Acad Sci U S A. 2005 May 17;102(20):7215-20. Erratum in: Proc Natl Acad Sci U S A. 2006 Sep 5;103(36):13560. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9374.


Rapamycin inhibits yeast nucleotide excision repair independently of tor kinases.

Limson MV, Sweder KS.

Toxicol Sci. 2010 Jan;113(1):77-84. doi: 10.1093/toxsci/kfp238.


TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast.

Helliwell SB, Wagner P, Kunz J, Deuter-Reinhard M, Henriquez R, Hall MN.

Mol Biol Cell. 1994 Jan;5(1):105-18.


Tor pathway control of the nitrogen-responsive DAL5 gene bifurcates at the level of Gln3 and Gat1 regulation in Saccharomyces cerevisiae.

Georis I, Tate JJ, Cooper TG, Dubois E.

J Biol Chem. 2008 Apr 4;283(14):8919-29. doi: 10.1074/jbc.M708811200.


TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin.

Zheng XF, Florentino D, Chen J, Crabtree GR, Schreiber SL.

Cell. 1995 Jul 14;82(1):121-30.


Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.

Loewith R, Jacinto E, Wullschleger S, Lorberg A, Crespo JL, Bonenfant D, Oppliger W, Jenoe P, Hall MN.

Mol Cell. 2002 Sep;10(3):457-68.


The TOR nutrient signalling pathway phosphorylates NPR1 and inhibits turnover of the tryptophan permease.

Schmidt A, Beck T, Koller A, Kunz J, Hall MN.

EMBO J. 1998 Dec 1;17(23):6924-31.


Mammalian RAFT1 kinase domain provides rapamycin-sensitive TOR function in yeast.

Alarcon CM, Cardenas ME, Heitman J.

Genes Dev. 1996 Feb 1;10(3):279-88.


TOR2 is part of two related signaling pathways coordinating cell growth in Saccharomyces cerevisiae.

Helliwell SB, Howald I, Barbet N, Hall MN.

Genetics. 1998 Jan;148(1):99-112.


Missense mutations at the FKBP12-rapamycin-binding site of TOR1.

Freeman K, Livi GP.

Gene. 1996 Jun 12;172(1):143-7.

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