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Items: 1 to 20 of 212

1.

PGE(2) inhibition of TGF-beta1-induced myofibroblast differentiation is Smad-independent but involves cell shape and adhesion-dependent signaling.

Thomas PE, Peters-Golden M, White ES, Thannickal VJ, Moore BB.

Am J Physiol Lung Cell Mol Physiol. 2007 Aug;293(2):L417-28. Epub 2007 Jun 8.

2.

Myofibroblast differentiation by transforming growth factor-beta1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase.

Thannickal VJ, Lee DY, White ES, Cui Z, Larios JM, Chacon R, Horowitz JC, Day RM, Thomas PE.

J Biol Chem. 2003 Apr 4;278(14):12384-9. Epub 2003 Jan 16.

3.

Combinatorial activation of FAK and AKT by transforming growth factor-beta1 confers an anoikis-resistant phenotype to myofibroblasts.

Horowitz JC, Rogers DS, Sharma V, Vittal R, White ES, Cui Z, Thannickal VJ.

Cell Signal. 2007 Apr;19(4):761-71. Epub 2006 Nov 17.

4.

Integrin-linked kinase is required for TGF-β1 induction of dermal myofibroblast differentiation.

Vi L, de Lasa C, DiGuglielmo GM, Dagnino L.

J Invest Dermatol. 2011 Mar;131(3):586-93. doi: 10.1038/jid.2010.362. Epub 2010 Dec 9.

5.

TGF-beta1-mediated fibroblast-myofibroblast terminal differentiation-the role of Smad proteins.

Evans RA, Tian YC, Steadman R, Phillips AO.

Exp Cell Res. 2003 Jan 15;282(2):90-100.

PMID:
12531695
6.

Sphingosine 1-phosphate (S1P) receptor agonists mediate pro-fibrotic responses in normal human lung fibroblasts via S1P2 and S1P3 receptors and Smad-independent signaling.

Sobel K, Menyhart K, Killer N, Renault B, Bauer Y, Studer R, Steiner B, Bolli MH, Nayler O, Gatfield J.

J Biol Chem. 2013 May 24;288(21):14839-51. doi: 10.1074/jbc.M112.426726. Epub 2013 Apr 15.

8.

Transforming growth factor-beta1 effects on endothelial monolayer permeability involve focal adhesion kinase/Src.

Lee YH, Kayyali US, Sousa AM, Rajan T, Lechleider RJ, Day RM.

Am J Respir Cell Mol Biol. 2007 Oct;37(4):485-93. Epub 2007 Jun 21.

9.

NAD(P)H oxidase mediates TGF-beta1-induced activation of kidney myofibroblasts.

Bondi CD, Manickam N, Lee DY, Block K, Gorin Y, Abboud HE, Barnes JL.

J Am Soc Nephrol. 2010 Jan;21(1):93-102. doi: 10.1681/ASN.2009020146. Epub 2009 Nov 19.

10.
11.

Epigenetic regulation of myofibroblast differentiation and extracellular matrix production in nasal polyp-derived fibroblasts.

Cho JS, Moon YM, Park IH, Um JY, Moon JH, Park SJ, Lee SH, Kang HJ, Lee HM.

Clin Exp Allergy. 2012 Jun;42(6):872-82. doi: 10.1111/j.1365-2222.2011.03931.x.

PMID:
22239687
12.

Aspidin PB, a novel natural anti-fibrotic compound, inhibited fibrogenesis in TGF-β1-stimulated keloid fibroblasts via PI-3K/Akt and Smad signaling pathways.

Song R, Li G, Li S.

Chem Biol Interact. 2015 Aug 5;238:66-73. doi: 10.1016/j.cbi.2015.06.005. Epub 2015 Jun 6.

PMID:
26054450
13.
15.

Sodium tanshinone IIA sulfonate attenuates the transforming growth factor-β1-induced differentiation of atrial fibroblasts into myofibroblasts in vitro.

Yang L, Hu J, Hao HZ, Yin Z, Liu G, Zou XJ.

Int J Mol Med. 2015 Apr;35(4):1026-32. doi: 10.3892/ijmm.2015.2087. Epub 2015 Feb 2.

PMID:
25647570
16.

Silencing NLRC5 inhibits extracellular matrix expression in keloid fibroblasts via inhibition of transforming growth factor-β1/Smad signaling pathway.

Ma HL, Zhao XF, Chen GZ, Fang RH, Zhang FR.

Biomed Pharmacother. 2016 Oct;83:1016-1021. doi: 10.1016/j.biopha.2016.08.012. Epub 2016 Aug 12.

PMID:
27525969
17.

Identifying Mechanisms of Homeostatic Signaling in Fibroblast Differentiation.

Warsinske HC, Ashley SL, Linderman JJ, Moore BB, Kirschner DE.

Bull Math Biol. 2015 Aug;77(8):1556-82. doi: 10.1007/s11538-015-0096-2. Epub 2015 Sep 18.

18.

Hydroxysafflor yellow A inhibits TGF-β1-induced activation of human fetal lung fibroblasts in vitro.

Pan R, Zhang Y, Zang B, Tan L, Jin M.

J Pharm Pharmacol. 2016 Oct;68(10):1320-30. doi: 10.1111/jphp.12596. Epub 2016 Jul 26.

PMID:
27457091
19.

The antifibrotic effects of relaxin in human renal fibroblasts are mediated in part by inhibition of the Smad2 pathway.

Heeg MH, Koziolek MJ, Vasko R, Schaefer L, Sharma K, Müller GA, Strutz F.

Kidney Int. 2005 Jul;68(1):96-109.

20.

Transforming growth factor-β(1) represses bone morphogenetic protein-mediated Smad signaling in pulmonary artery smooth muscle cells via Smad3.

Upton PD, Davies RJ, Tajsic T, Morrell NW.

Am J Respir Cell Mol Biol. 2013 Dec;49(6):1135-45. doi: 10.1165/rcmb.2012-0470OC.

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