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Items: 1 to 20 of 63

1.

The interferon inducing pathways and the hepatitis C virus.

Meurs EF, Breiman A.

World J Gastroenterol. 2007 May 7;13(17):2446-54. Review.

2.

Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKepsilon.

Breiman A, Grandvaux N, Lin R, Ottone C, Akira S, Yoneyama M, Fujita T, Hiscott J, Meurs EF.

J Virol. 2005 Apr;79(7):3969-78.

3.

Induction of IRF-3 and IRF-7 phosphorylation following activation of the RIG-I pathway.

Paz S, Sun Q, Nakhaei P, Romieu-Mourez R, Goubau D, Julkunen I, Lin R, Hiscott J.

Cell Mol Biol (Noisy-le-grand). 2006 May 15;52(1):17-28.

PMID:
16914100
4.

Hepatitis C virus reveals a novel early control in acute immune response.

Arnaud N, Dabo S, Akazawa D, Fukasawa M, Shinkai-Ouchi F, Hugon J, Wakita T, Meurs EF.

PLoS Pathog. 2011 Oct;7(10):e1002289. doi: 10.1371/journal.ppat.1002289. Epub 2011 Oct 13.

5.

Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression.

Kaukinen P, Sillanpää M, Kotenko S, Lin R, Hiscott J, Melén K, Julkunen I.

Virol J. 2006 Sep 1;3:66.

6.

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus.

Meylan E, Curran J, Hofmann K, Moradpour D, Binder M, Bartenschlager R, Tschopp J.

Nature. 2005 Oct 20;437(7062):1167-72. Epub 2005 Sep 21.

PMID:
16177806
7.

Recruitment of an interferon molecular signaling complex to the mitochondrial membrane: disruption by hepatitis C virus NS3-4A protease.

Hiscott J, Lacoste J, Lin R.

Biochem Pharmacol. 2006 Nov 30;72(11):1477-84. Epub 2006 Jul 31.

PMID:
16876765
8.

Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKepsilon molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavage.

Lin R, Lacoste J, Nakhaei P, Sun Q, Yang L, Paz S, Wilkinson P, Julkunen I, Vitour D, Meurs E, Hiscott J.

J Virol. 2006 Jun;80(12):6072-83.

9.

Hepatitis A and hepatitis C viruses: divergent infection outcomes marked by similarities in induction and evasion of interferon responses.

Qu L, Lemon SM.

Semin Liver Dis. 2010 Nov;30(4):319-32. doi: 10.1055/s-0030-1267534. Epub 2010 Oct 19. Review.

PMID:
20960373
10.

The protein kinase IKKepsilon can inhibit HCV expression independently of IFN and its own expression is downregulated in HCV-infected livers.

Vilasco M, Larrea E, Vitour D, Dabo S, Breiman A, Regnault B, Riezu JI, Eid P, Prieto J, Meurs EF.

Hepatology. 2006 Dec;44(6):1635-47.

PMID:
17133498
11.

Hepatitis C virus variants resistant to macrocyclic NS3-4A inhibitors subvert IFN-β induction by efficient MAVS cleavage.

Welsch C, Haselow K, Gouttenoire J, Schneider M, Morikawa K, Martinez Y, Susser S, Sarrazin C, Zeuzem S, Antes I, Moradpour D, Lange CM.

J Hepatol. 2015 Apr;62(4):779-84. doi: 10.1016/j.jhep.2014.11.009. Epub 2014 Nov 21.

PMID:
25463536
12.

Innate immunity and HCV.

Heim MH.

J Hepatol. 2013 Mar;58(3):564-74. doi: 10.1016/j.jhep.2012.10.005. Epub 2012 Oct 11. Review.

13.

NAK-associated protein 1 participates in both the TLR3 and the cytoplasmic pathways in type I IFN induction.

Sasai M, Shingai M, Funami K, Yoneyama M, Fujita T, Matsumoto M, Seya T.

J Immunol. 2006 Dec 15;177(12):8676-83.

14.

GB virus B disrupts RIG-I signaling by NS3/4A-mediated cleavage of the adaptor protein MAVS.

Chen Z, Benureau Y, Rijnbrand R, Yi J, Wang T, Warter L, Lanford RE, Weinman SA, Lemon SM, Martin A, Li K.

J Virol. 2007 Jan;81(2):964-76. Epub 2006 Nov 8.

15.

Activation of Type I and III Interferon Response by Mitochondrial and Peroxisomal MAVS and Inhibition by Hepatitis C Virus.

Bender S, Reuter A, Eberle F, Einhorn E, Binder M, Bartenschlager R.

PLoS Pathog. 2015 Nov 20;11(11):e1005264. doi: 10.1371/journal.ppat.1005264. eCollection 2015 Nov.

16.

Hepatitis C virus NS2 protease inhibits host cell antiviral response by inhibiting IKKε and TBK1 functions.

Kaukinen P, Sillanpää M, Nousiainen L, Melén K, Julkunen I.

J Med Virol. 2013 Jan;85(1):71-82. doi: 10.1002/jmv.23442. Epub 2012 Oct 23.

PMID:
23096996
17.

Hepatitis C virus controls interferon production through PKR activation.

Arnaud N, Dabo S, Maillard P, Budkowska A, Kalliampakou KI, Mavromara P, Garcin D, Hugon J, Gatignol A, Akazawa D, Wakita T, Meurs EF.

PLoS One. 2010 May 11;5(5):e10575. doi: 10.1371/journal.pone.0010575.

18.

Hepatitis C virus core protein abrogates the DDX3 function that enhances IPS-1-mediated IFN-beta induction.

Oshiumi H, Ikeda M, Matsumoto M, Watanabe A, Takeuchi O, Akira S, Kato N, Shimotohno K, Seya T.

PLoS One. 2010 Dec 8;5(12):e14258. doi: 10.1371/journal.pone.0014258.

19.

Interaction between the HCV NS3 protein and the host TBK1 protein leads to inhibition of cellular antiviral responses.

Otsuka M, Kato N, Moriyama M, Taniguchi H, Wang Y, Dharel N, Kawabe T, Omata M.

Hepatology. 2005 May;41(5):1004-12.

PMID:
15841462
20.

[Role of IPS-1 in type I IFN induction].

Kawai T, Akira S.

Nihon Rinsho. 2006 Jul;64(7):1231-5. Review. Japanese.

PMID:
16841392

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