Similar articles for PMID: 17545584

Year	Number of Results
1991	1
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2002	4
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2024	0

1

Mel-18 acts as a tumor suppressor by repressing Bmi-1 expression and down-regulating Akt activity in breast cancer cells.

Guo WJ, Zeng MS, Yadav A, Song LB, Guo BH, Band V, Dimri GP. Guo WJ, et al. Cancer Res. 2007 Jun 1;67(11):5083-9. doi: 10.1158/0008-5472.CAN-06-4368. Cancer Res. 2007. PMID: 17545584 Free PMC article.

2

Implication of polycomb members Bmi-1, Mel-18, and Hpc-2 in the regulation of p16INK4a, p14ARF, h-TERT, and c-Myc expression in primary breast carcinomas.

Silva J, García JM, Peña C, García V, Domínguez G, Suárez D, Camacho FI, Espinosa R, Provencio M, España P, Bonilla F. Silva J, et al. Clin Cancer Res. 2006 Dec 1;12(23):6929-36. doi: 10.1158/1078-0432.CCR-06-0788. Clin Cancer Res. 2006. PMID: 17145810

3

BMI1 and Mel-18 oppositely regulate carcinogenesis and progression of gastric cancer.

Zhang XW, Sheng YP, Li Q, Qin W, Lu YW, Cheng YF, Liu BY, Zhang FC, Li J, Dimri GP, Guo WJ. Zhang XW, et al. Mol Cancer. 2010 Feb 21;9:40. doi: 10.1186/1476-4598-9-40. Mol Cancer. 2010. PMID: 20170541 Free PMC article.

4

Mel-18 negatively regulates INK4a/ARF-independent cell cycle progression via Akt inactivation in breast cancer.

Lee JY, Jang KS, Shin DH, Oh MY, Kim HJ, Kim Y, Kong G. Lee JY, et al. Cancer Res. 2008 Jun 1;68(11):4201-9. doi: 10.1158/0008-5472.CAN-07-2570. Cancer Res. 2008. PMID: 18519679 Free article.

5

Contribution of polycomb homologues Bmi-1 and Mel-18 to medulloblastoma pathogenesis.

Wiederschain D, Chen L, Johnson B, Bettano K, Jackson D, Taraszka J, Wang YK, Jones MD, Morrissey M, Deeds J, Mosher R, Fordjour P, Lengauer C, Benson JD. Wiederschain D, et al. Mol Cell Biol. 2007 Jul;27(13):4968-79. doi: 10.1128/MCB.02244-06. Epub 2007 Apr 23. Mol Cell Biol. 2007. PMID: 17452456 Free PMC article.

6

Loss of Mel-18 induces tumor angiogenesis through enhancing the activity and expression of HIF-1α mediated by the PTEN/PI3K/Akt pathway.

Park JH, Lee JY, Shin DH, Jang KS, Kim HJ, Kong G. Park JH, et al. Oncogene. 2011 Nov 10;30(45):4578-89. doi: 10.1038/onc.2011.174. Epub 2011 May 23. Oncogene. 2011. PMID: 21602890

7

The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells.

Dimri GP, Martinez JL, Jacobs JJ, Keblusek P, Itahana K, Van Lohuizen M, Campisi J, Wazer DE, Band V. Dimri GP, et al. Cancer Res. 2002 Aug 15;62(16):4736-45. Cancer Res. 2002. PMID: 12183433

8

Mel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteins.

Guo WJ, Datta S, Band V, Dimri GP. Guo WJ, et al. Mol Biol Cell. 2007 Feb;18(2):536-46. doi: 10.1091/mbc.e06-05-0447. Epub 2006 Dec 6. Mol Biol Cell. 2007. PMID: 17151361 Free PMC article.

9

Id1 enhances RING1b E3 ubiquitin ligase activity through the Mel-18/Bmi-1 polycomb group complex.

Qian T, Lee JY, Park JH, Kim HJ, Kong G. Qian T, et al. Oncogene. 2010 Oct 28;29(43):5818-27. doi: 10.1038/onc.2010.317. Epub 2010 Aug 9. Oncogene. 2010. PMID: 20697353

10

Knockdown of the Bmi-1 oncogene inhibits cell proliferation and induces cell apoptosis and is involved in the decrease of Akt phosphorylation in the human breast carcinoma cell line MCF-7.

Xu Z, Liu H, Lv X, Liu Y, Li S, Li H. Xu Z, et al. Oncol Rep. 2011 Feb;25(2):409-18. doi: 10.3892/or.2010.1078. Epub 2010 Dec 7. Oncol Rep. 2011. PMID: 21152871

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