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Items: 1 to 20 of 79

1.

Spontaneous mutations in the mouse Sharpin gene result in multiorgan inflammation, immune system dysregulation and dermatitis.

Seymour RE, Hasham MG, Cox GA, Shultz LD, Hogenesch H, Roopenian DC, Sundberg JP.

Genes Immun. 2007 Jul;8(5):416-21. Epub 2007 May 31.

PMID:
17538631
2.

Absence of Peyer's patches and abnormal lymphoid architecture in chronic proliferative dermatitis (cpdm/cpdm) mice.

HogenEsch H, Janke S, Boggess D, Sundberg JP.

J Immunol. 1999 Apr 1;162(7):3890-6.

3.

Sharpin, a novel postsynaptic density protein that directly interacts with the shank family of proteins.

Lim S, Sala C, Yoon J, Park S, Kuroda S, Sheng M, Kim E.

Mol Cell Neurosci. 2001 Feb;17(2):385-97.

PMID:
11178875
4.

Loss-of-function of SHARPIN causes an osteopenic phenotype in mice.

Xia T, Liang Y, Ma J, Li M, Gong M, Yu X.

Endocrine. 2011 Apr;39(2):104-12. doi: 10.1007/s12020-010-9418-1. Epub 2010 Nov 11.

PMID:
21069580
5.

Chronic proliferative dermatitis in Sharpin null mice: development of an autoinflammatory disease in the absence of B and T lymphocytes and IL4/IL13 signaling.

Potter CS, Wang Z, Silva KA, Kennedy VE, Stearns TM, Burzenski L, Shultz LD, Hogenesch H, Sundberg JP.

PLoS One. 2014 Jan 21;9(1):e85666. doi: 10.1371/journal.pone.0085666. eCollection 2014.

6.

SHARPIN is a key regulator of immune and inflammatory responses.

Wang Z, Potter CS, Sundberg JP, Hogenesch H.

J Cell Mol Med. 2012 Oct;16(10):2271-9. doi: 10.1111/j.1582-4934.2012.01574.x. Review.

7.

Inhibition of NF-κB signaling retards eosinophilic dermatitis in SHARPIN-deficient mice.

Liang Y, Seymour RE, Sundberg JP.

J Invest Dermatol. 2011 Jan;131(1):141-9. doi: 10.1038/jid.2010.259. Epub 2010 Sep 2.

8.

Anti-IL5 decreases the number of eosinophils but not the severity of dermatitis in Sharpin-deficient mice.

Renninger ML, Seymour RE, Whiteley LO, Sundberg JP, Hogenesch H.

Exp Dermatol. 2010 Mar;19(3):252-8. doi: 10.1111/j.1600-0625.2009.00944.x. Epub 2009 Jul 23.

9.

Newly identified tumor-associated role of human Sharpin.

Jung J, Kim JM, Park B, Cheon Y, Lee B, Choo SH, Koh SS, Lee S.

Mol Cell Biochem. 2010 Jul;340(1-2):161-7. doi: 10.1007/s11010-010-0413-x. Epub 2010 Feb 24.

PMID:
20179993
10.

Therapeutic interventions in mice with chronic proliferative dermatitis (cpdm/cpdm).

Gijbels MJ, Elliott GR, HogenEsch H, Zurcher C, van den Hoven A, Bruijnzeel PL.

Exp Dermatol. 2000 Oct;9(5):351-8.

PMID:
11016856
11.

TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice.

Rickard JA, Anderton H, Etemadi N, Nachbur U, Darding M, Peltzer N, Lalaoui N, Lawlor KE, Vanyai H, Hall C, Bankovacki A, Gangoda L, Wong WW, Corbin J, Huang C, Mocarski ES, Murphy JM, Alexander WS, Voss AK, Vaux DL, Kaiser WJ, Walczak H, Silke J.

Elife. 2014 Dec 2;3. doi: 10.7554/eLife.03464.

12.

Pathogenesis of skin lesions in mice with chronic proliferative dermatitis (cpdm/cpdm).

Gijbels MJ, Zurcher C, Kraal G, Elliott GR, HogenEsch H, Schijff G, Savelkoul HF, Bruijnzeel PL.

Am J Pathol. 1996 Mar;148(3):941-50.

13.

Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses.

Zak DE, Schmitz F, Gold ES, Diercks AH, Peschon JJ, Valvo JS, Niemistö A, Podolsky I, Fallen SG, Suen R, Stolyar T, Johnson CD, Kennedy KA, Hamilton MK, Siggs OM, Beutler B, Aderem A.

Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11536-41. doi: 10.1073/pnas.1107577108. Epub 2011 Jun 27.

14.

SHARPIN regulates mitochondria-dependent apoptosis in keratinocytes.

Liang Y, Sundberg JP.

J Dermatol Sci. 2011 Sep;63(3):148-53. doi: 10.1016/j.jdermsci.2011.04.012. Epub 2011 May 7.

15.

Loss of function of the mouse Sharpin gene results in Peyer's patch regression.

Seymour R, Shirley BJ, Hogenesch H, Shultz LD, Sundberg JP.

PLoS One. 2013;8(2):e55224. doi: 10.1371/journal.pone.0055224. Epub 2013 Feb 12.

16.

Sharpin Controls Osteogenic Differentiation of Mesenchymal Bone Marrow Cells.

Jeschke A, Catala-Lehnen P, Sieber S, Bickert T, Schweizer M, Koehne T, Wintges K, Marshall RP, Mautner A, Duchstein L, Otto B, Horst AK, Amling M, Kreienkamp HJ, Schinke T.

J Immunol. 2015 Oct 15;195(8):3675-84. doi: 10.4049/jimmunol.1402392. Epub 2015 Sep 11.

17.

Expression of chitinase-like proteins in the skin of chronic proliferative dermatitis (cpdm/cpdm) mice.

HogenEsch H, Dunham A, Seymour R, Renninger M, Sundberg JP.

Exp Dermatol. 2006 Oct;15(10):808-14.

PMID:
16984263
18.

Distinct role of IL-1β in instigating disease in Sharpincpdm mice.

Gurung P, Sharma BR, Kanneganti TD.

Sci Rep. 2016 Nov 28;6:36634. doi: 10.1038/srep36634.

19.
20.

Loss of FAS/FASL signaling does not reduce apoptosis in Sharpin null mice.

Potter CS, Silva KA, Kennedy VE, Stearns TM, HogenEsch H, Sundberg JP.

Exp Dermatol. 2017 Jan 17. doi: 10.1111/exd.13289. [Epub ahead of print]

PMID:
28094869

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