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Amelioration of pain and histopathologic joint abnormalities in the Col1-IL-1beta(XAT) mouse model of arthritis by intraarticular induction of mu-opioid receptor into the temporomandibular joint.

Kyrkanides S, Fiorentino PM, Miller JN, Gan Y, Lai YC, Shaftel SS, Puzas JE, Piancino MG, O'Banion MK, Tallents RH.

Arthritis Rheum. 2007 Jun;56(6):2038-48.


Spinal interleukin-1beta in a mouse model of arthritis and joint pain.

Fiorentino PM, Tallents RH, Miller JN, Brouxhon SM, O'Banion MK, Puzas JE, Kyrkanides S.

Arthritis Rheum. 2008 Oct;58(10):3100-9. doi: 10.1002/art.23866.


Intraarticular induction of interleukin-1beta expression in the adult mouse, with resultant temporomandibular joint pathologic changes, dysfunction, and pain.

Lai YC, Shaftel SS, Miller JN, Tallents RH, Chang Y, Pinkert CA, Olschowka JA, Dickerson IM, Puzas JE, O'Banion MK, Kyrkanides S.

Arthritis Rheum. 2006 Apr;54(4):1184-97.


Shift from toll-like receptor 2 (TLR-2) toward TLR-4 dependency in the erosive stage of chronic streptococcal cell wall arthritis coincident with TLR-4-mediated interleukin-17 production.

Abdollahi-Roodsaz S, Joosten LA, Helsen MM, Walgreen B, van Lent PL, van den Bersselaar LA, Koenders MI, van den Berg WB.

Arthritis Rheum. 2008 Dec;58(12):3753-64. doi: 10.1002/art.24127.


Effects of capsaicin in temporomandibular joint arthritis in rats.

Carleson J, Kogner P, Bileviciute I, Theodorsson E, Appelgren A, Appelgren B, Kopp S, Yousef N, Lundeberg T.

Arch Oral Biol. 1997 Dec;42(12):869-76.


Role of Wnt-5A in interleukin-1beta-induced matrix metalloproteinase expression in rabbit temporomandibular joint condylar chondrocytes.

Ge X, Ma X, Meng J, Zhang C, Ma K, Zhou C.

Arthritis Rheum. 2009 Sep;60(9):2714-22. doi: 10.1002/art.24779.


Ex vivo gene delivery of IL-1Ra and soluble TNF receptor confers a distal synergistic therapeutic effect in antigen-induced arthritis.

Kim SH, Lechman ER, Kim S, Nash J, Oligino TJ, Robbins PD.

Mol Ther. 2002 Nov;6(5):591-600.


Interleukin-1beta in antigen-induced arthritis of the rabbit temporomandibular joint.

Tominaga K, Alstergren P, Kurita H, Matsukawa A, Fukuda J, Kopp S.

Arch Oral Biol. 2001 Jun;46(6):539-44.


Scavenger receptor class A type I/II determines matrix metalloproteinase-mediated cartilage destruction and chondrocyte death in antigen-induced arthritis.

van Lent PL, Hofkens W, Blom AB, Grevers L, Sloetjes A, Takahashi N, van Tits LJ, Vogl T, Roth J, de Winther MP, van den Berg WB.

Arthritis Rheum. 2009 Oct;60(10):2954-65. doi: 10.1002/art.24908.


IL-1beta inhibits TGFbeta in the temporomandibular joint.

Lim WH, Toothman J, Miller JH, Tallents RH, Brouxhon SM, Olschowka ME, Kyrkanides S.

J Dent Res. 2009 Jun;88(6):557-62. doi: 10.1177/0022034509336823.


Nerve growth factor induced after temporomandibular joint inflammation decelerates chondrocyte differentiation.

Huang H, Shank G, Ma L, Tallents RH, Kyrkanides S.

Oral Dis. 2013 Sep;19(6):604-10. doi: 10.1111/odi.12045. Epub 2012 Dec 12.


Interleukin-17 sensitizes joint nociceptors to mechanical stimuli and contributes to arthritic pain through neuronal interleukin-17 receptors in rodents.

Richter F, Natura G, Ebbinghaus M, von Banchet GS, Hensellek S, König C, Bräuer R, Schaible HG.

Arthritis Rheum. 2012 Dec;64(12):4125-34. doi: 10.1002/art.37695.


Gonadal hormones decrease temporomandibular joint kappa-mediated antinociception through a down-regulation in the expression of kappa opioid receptors in the trigeminal ganglia.

Clemente-Napimoga JT, Pellegrini-da-Silva A, Ferreira VH, Napimoga MH, Parada CA, Tambeli CH.

Eur J Pharmacol. 2009 Sep 1;617(1-3):41-7. doi: 10.1016/j.ejphar.2009.06.036. Epub 2009 Jun 28.


The role of interleukin-1β in arthritic pain: main involvement in thermal, but not mechanical, hyperalgesia in rat antigen-induced arthritis.

Ebbinghaus M, Uhlig B, Richter F, von Banchet GS, Gajda M, Bräuer R, Schaible HG.

Arthritis Rheum. 2012 Dec;64(12):3897-907. doi: 10.1002/art.34675.


T cell dependence of chronic destructive murine arthritis induced by repeated local activation of Toll-like receptor-driven pathways: crucial role of both interleukin-1beta and interleukin-17.

Joosten LA, Abdollahi-Roodsaz S, Heuvelmans-Jacobs M, Helsen MM, van den Bersselaar LA, Oppers-Walgreen B, Koenders MI, van den Berg WB.

Arthritis Rheum. 2008 Jan;58(1):98-108. doi: 10.1002/art.23152.


CB(2) cannabinoid receptor antagonist SR144528 decreases mu-opioid receptor expression and activation in mouse brainstem: role of CB(2) receptor in pain.

Páldy E, Bereczki E, Sántha M, Wenger T, Borsodi A, Zimmer A, Benyhe S.

Neurochem Int. 2008 Dec;53(6-8):309-16. doi: 10.1016/j.neuint.2008.08.005. Epub 2008 Aug 29.


Interleukin-1beta in synovial fluid from the arthritic temporomandibular joint and its relation to pain, mobility, and anterior open bite.

Alstergren P, Ernberg M, Kvarnström M, Kopp S.

J Oral Maxillofac Surg. 1998 Sep;56(9):1059-65; discussion 1066.


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