Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 79


ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER 3rd, Hurov KE, Luo J, Bakalarski CE, Zhao Z, Solimini N, Lerenthal Y, Shiloh Y, Gygi SP, Elledge SJ.

Science. 2007 May 25;316(5828):1160-6.


A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints.

Mu JJ, Wang Y, Luo H, Leng M, Zhang J, Yang T, Besusso D, Jung SY, Qin J.

J Biol Chem. 2007 Jun 15;282(24):17330-4. Epub 2007 May 3.


DNA replication stress-induced phosphorylation of cyclic AMP response element-binding protein mediated by ATM.

Dodson GE, Tibbetts RS.

J Biol Chem. 2006 Jan 20;281(3):1692-7. Epub 2005 Nov 17.


ATM is required for the cellular response to thymidine induced replication fork stress.

Bolderson E, Scorah J, Helleday T, Smythe C, Meuth M.

Hum Mol Genet. 2004 Dec 1;13(23):2937-45. Epub 2004 Sep 30.


Transgenic expression of E2F3a causes DNA damage leading to ATM-dependent apoptosis.

Paulson QX, Pusapati RV, Hong S, Weaks RL, Conti CJ, Johnson DG.

Oncogene. 2008 Aug 21;27(36):4954-61. doi: 10.1038/onc.2008.138. Epub 2008 May 12.


Identification of domains of ataxia-telangiectasia mutated required for nuclear localization and chromatin association.

Young DB, Jonnalagadda J, Gatei M, Jans DA, Meyn S, Khanna KK.

J Biol Chem. 2005 Jul 29;280(30):27587-94. Epub 2005 Jun 1.


Ataxia-telangiectasia-mutated (ATM) is a T-antigen kinase that controls SV40 viral replication in vivo.

Shi Y, Dodson GE, Shaikh S, Rundell K, Tibbetts RS.

J Biol Chem. 2005 Dec 2;280(48):40195-200. Epub 2005 Oct 11.


Activation of ataxia telangiectasia-mutated DNA damage checkpoint signal transduction elicited by herpes simplex virus infection.

Shirata N, Kudoh A, Daikoku T, Tatsumi Y, Fujita M, Kiyono T, Sugaya Y, Isomura H, Ishizaki K, Tsurumi T.

J Biol Chem. 2005 Aug 26;280(34):30336-41. Epub 2005 Jun 17.


Epstein-Barr virus lytic replication elicits ATM checkpoint signal transduction while providing an S-phase-like cellular environment.

Kudoh A, Fujita M, Zhang L, Shirata N, Daikoku T, Sugaya Y, Isomura H, Nishiyama Y, Tsurumi T.

J Biol Chem. 2005 Mar 4;280(9):8156-63. Epub 2004 Dec 15.


Roles of nibrin and AtM/ATR kinases on the G2 checkpoint under endogenous or radio-induced DNA damage.

Marcelain K, De La Torre C, González P, Pincheira J.

Biol Res. 2005;38(2-3):179-85.


Identification of a PP2A-interacting protein that functions as a negative regulator of phosphatase activity in the ATM/ATR signaling pathway.

McConnell JL, Gomez RJ, McCorvey LR, Law BK, Wadzinski BE.

Oncogene. 2007 Sep 6;26(41):6021-30. Epub 2007 Mar 26.


Profiling of UV-induced ATM/ATR signaling pathways.

Stokes MP, Rush J, Macneill J, Ren JM, Sprott K, Nardone J, Yang V, Beausoleil SA, Gygi SP, Livingstone M, Zhang H, Polakiewicz RD, Comb MJ.

Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19855-60. Epub 2007 Dec 6.


ATM- and ATR-mediated response to DNA damage induced by a novel camptothecin, ST1968.

Zuco V, Benedetti V, Zunino F.

Cancer Lett. 2010 Jun 28;292(2):186-96. doi: 10.1016/j.canlet.2009.12.001. Epub 2009 Dec 29.


Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites.

So S, Davis AJ, Chen DJ.

J Cell Biol. 2009 Dec 28;187(7):977-90. doi: 10.1083/jcb.200906064. Epub 2009 Dec 21. Erratum in: J Cell Biol. 2010 Feb 8;188(3):443.


Identification of an ataxia telangiectasia-mutated protein mediated surveillance system to regulate Bcl-2 overexpression.

Zhang J, Lahti JM, Bruce A, He L, Parihar K, Fan C, Grenet J, Liu L, Kidd VJ, Cormier S, Tang D.

Oncogene. 2006 Sep 14;25(41):5601-11. Epub 2006 Apr 24.


Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G(1)/S checkpoint activation in response to DNA damage.

Post S, Weng YC, Cimprich K, Chen LB, Xu Y, Lee EY.

Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13102-7. Epub 2001 Oct 30.


Ataxia-telangiectasia mutated (ATM)-dependent activation of ATR occurs through phosphorylation of TopBP1 by ATM.

Yoo HY, Kumagai A, Shevchenko A, Shevchenko A, Dunphy WG.

J Biol Chem. 2007 Jun 15;282(24):17501-6. Epub 2007 Apr 19.

Supplemental Content

Support Center