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Items: 1 to 20 of 95

1.

Eps8 facilitates cellular growth and motility of colon cancer cells by increasing the expression and activity of focal adhesion kinase.

Maa MC, Lee JC, Chen YJ, Chen YJ, Lee YC, Wang ST, Huang CC, Chow NH, Leu TH.

J Biol Chem. 2007 Jul 6;282(27):19399-409. Epub 2007 May 12.

2.

The interplay between Eps8 and IRSp53 contributes to Src-mediated transformation.

Liu PS, Jong TH, Maa MC, Leu TH.

Oncogene. 2010 Jul 8;29(27):3977-89. doi: 10.1038/onc.2010.144. Epub 2010 Apr 26.

PMID:
20418908
3.

Butyrate regulates the expression of c-Src and focal adhesion kinase and inhibits cell invasion of human colon cancer cells.

Lee JC, Maa MC, Yu HS, Wang JH, Yen CK, Wang ST, Chen YJ, Liu Y, Jin YT, Leu TH.

Mol Carcinog. 2005 Aug;43(4):207-14.

PMID:
16001424
4.

Eps8 decreases chemosensitivity and affects survival of cervical cancer patients.

Chen YJ, Shen MR, Chen YJ, Maa MC, Leu TH.

Mol Cancer Ther. 2008 Jun;7(6):1376-85. doi: 10.1158/1535-7163.MCT-07-2388.

5.

Tumor necrosis factor-alpha stimulates focal adhesion kinase activity required for mitogen-activated kinase-associated interleukin 6 expression.

Schlaepfer DD, Hou S, Lim ST, Tomar A, Yu H, Lim Y, Hanson DA, Uryu SA, Molina J, Mitra SK.

J Biol Chem. 2007 Jun 15;282(24):17450-9. Epub 2007 Apr 16.

6.

Deoxycholic acid differentially regulates focal adhesion kinase phosphorylation: role of tyrosine phosphatase ShP2.

Khare S, Holgren C, Samarel AM.

Am J Physiol Gastrointest Liver Physiol. 2006 Dec;291(6):G1100-12. Epub 2006 Aug 17.

7.
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Secreted LOXL2 is a novel therapeutic target that promotes gastric cancer metastasis via the Src/FAK pathway.

Peng L, Ran YL, Hu H, Yu L, Liu Q, Zhou Z, Sun YM, Sun LC, Pan J, Sun LX, Zhao P, Yang ZH.

Carcinogenesis. 2009 Oct;30(10):1660-9. doi: 10.1093/carcin/bgp178. Epub 2009 Jul 22.

PMID:
19625348
10.

Tumor growth inhibition by synthetic and expressed siRNA targeting focal adhesion kinase.

Tsutsumi K, Kasaoka T, Park HM, Nishiyama H, Nakajima M, Honda T.

Int J Oncol. 2008 Jul;33(1):215-24.

PMID:
18575768
11.

Overexpression of focal adhesion kinase in head and neck squamous cell carcinoma is independent of fak gene copy number.

Canel M, Secades P, Rodrigo JP, Cabanillas R, Herrero A, Suarez C, Chiara MD.

Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3272-9.

12.

Upregulation of Eps8 in oral squamous cell carcinoma promotes cell migration and invasion through integrin-dependent Rac1 activation.

Yap LF, Jenei V, Robinson CM, Moutasim K, Benn TM, Threadgold SP, Lopes V, Wei W, Thomas GJ, Paterson IC.

Oncogene. 2009 Jul 9;28(27):2524-34. doi: 10.1038/onc.2009.105. Epub 2009 May 18.

PMID:
19448673
13.

Leptin stimulates the migration of colon carcinoma cells by multiple signaling pathways.

Ratke J, Entschladen F, Niggemann B, Zänker KS, Lang K.

Endocr Relat Cancer. 2010 Feb 18;17(1):179-89. doi: 10.1677/ERC-09-0225. Print 2010 Mar.

14.

Focal adhesion kinase controls aggressive phenotype of androgen-independent prostate cancer.

Johnson TR, Khandrika L, Kumar B, Venezia S, Koul S, Chandhoke R, Maroni P, Donohue R, Meacham RB, Koul HK.

Mol Cancer Res. 2008 Oct;6(10):1639-48. doi: 10.1158/1541-7786.MCR-08-0052.

15.

FAK phosphorylation at Ser-843 inhibits Tyr-397 phosphorylation, cell spreading and migration.

Jacamo R, Jiang X, Lunn JA, Rozengurt E.

J Cell Physiol. 2007 Feb;210(2):436-44.

PMID:
17096371
16.

Insulin-like growth factor 1 receptor activates c-SRC and modifies transformation and motility of colon cancer in vitro.

Sekharam M, Nasir A, Kaiser HE, Coppola D.

Anticancer Res. 2003 Mar-Apr;23(2B):1517-24.

PMID:
12820418
17.

C-FLIP promotes the motility of cancer cells by activating FAK and ERK, and increasing MMP-9 expression.

Park D, Shim E, Kim Y, Kim YM, Lee H, Choe J, Kang D, Lee YS, Jeoung D.

Mol Cells. 2008 Apr 30;25(2):184-95. Epub 2008 Mar 28.

18.

FAK expression regulation and therapeutic potential.

Li S, Hua ZC.

Adv Cancer Res. 2008;101:45-61. doi: 10.1016/S0065-230X(08)00403-X. Review.

PMID:
19055942
19.

Silencing of focal adhesion kinase by tumor direct injection of small interfering RNA decreases in vivo tumor growth.

Tsutsumi K, Yamaura T, Nakajima M, Honda T, Kasaoka T.

Cancer Biol Ther. 2009 Jul;8(13):1292-9.

PMID:
19458494
20.

Src and FAK mediate cell-matrix adhesion-dependent activation of Met during transformation of breast epithelial cells.

Hui AY, Meens JA, Schick C, Organ SL, Qiao H, Tremblay EA, Schaeffer E, Uniyal S, Chan BM, Elliott BE.

J Cell Biochem. 2009 Aug 15;107(6):1168-81. doi: 10.1002/jcb.22219.

PMID:
19533669

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