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Items: 1 to 20 of 91

1.

Shox2 is required for chondrocyte proliferation and maturation in proximal limb skeleton.

Yu L, Liu H, Yan M, Yang J, Long F, Muneoka K, Chen Y.

Dev Biol. 2007 Jun 15;306(2):549-59. Epub 2007 Apr 1.

2.

Shox2 regulates progression through chondrogenesis in the mouse proximal limb.

Bobick BE, Cobb J.

J Cell Sci. 2012 Dec 15;125(Pt 24):6071-83. doi: 10.1242/jcs.111997. Epub 2012 Oct 4.

3.

A mouse model for human short-stature syndromes identifies Shox2 as an upstream regulator of Runx2 during long-bone development.

Cobb J, Dierich A, Huss-Garcia Y, Duboule D.

Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4511-5. Epub 2006 Mar 13.

4.

Genetic interactions between Shox2 and Hox genes during the regional growth and development of the mouse limb.

Neufeld SJ, Wang F, Cobb J.

Genetics. 2014 Nov;198(3):1117-26. doi: 10.1534/genetics.114.167460. Epub 2014 Sep 11.

5.

Runx3/AML2/Cbfa3 regulates early and late chondrocyte differentiation.

Soung do Y, Dong Y, Wang Y, Zuscik MJ, Schwarz EM, O'Keefe RJ, Drissi H.

J Bone Miner Res. 2007 Aug;22(8):1260-70.

6.

Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog.

Yoshida CA, Yamamoto H, Fujita T, Furuichi T, Ito K, Inoue K, Yamana K, Zanma A, Takada K, Ito Y, Komori T.

Genes Dev. 2004 Apr 15;18(8):952-63.

7.

Replacing Shox2 with human SHOX leads to congenital disc degeneration of the temporomandibular joint in mice.

Li X, Liu H, Gu S, Liu C, Sun C, Zheng Y, Chen Y.

Cell Tissue Res. 2014 Feb;355(2):345-54. doi: 10.1007/s00441-013-1743-2. Epub 2013 Nov 19.

8.

NPPB and ACAN, two novel SHOX2 transcription targets implicated in skeletal development.

Aza-Carmona M, Barca-Tierno V, Hisado-Oliva A, Belinchón A, Gorbenko-del Blanco D, Rodriguez JI, Benito-Sanz S, Campos-Barros A, Heath KE.

PLoS One. 2014 Jan 8;9(1):e83104. doi: 10.1371/journal.pone.0083104. eCollection 2014.

9.

PTHrP prevents chondrocyte premature hypertrophy by inducing cyclin-D1-dependent Runx2 and Runx3 phosphorylation, ubiquitylation and proteasomal degradation.

Zhang M, Xie R, Hou W, Wang B, Shen R, Wang X, Wang Q, Zhu T, Jonason JH, Chen D.

J Cell Sci. 2009 May 1;122(Pt 9):1382-9. doi: 10.1242/jcs.040709. Epub 2009 Apr 7.

10.

FGFR3 is a target of the homeobox transcription factor SHOX in limb development.

Decker E, Durand C, Bender S, Rödelsperger C, Glaser A, Hecht J, Schneider KU, Rappold G.

Hum Mol Genet. 2011 Apr 15;20(8):1524-35. doi: 10.1093/hmg/ddr030. Epub 2011 Jan 27.

PMID:
21273290
11.

Hoxa11 and Hoxd11 regulate chondrocyte differentiation upstream of Runx2 and Shox2 in mice.

Gross S, Krause Y, Wuelling M, Vortkamp A.

PLoS One. 2012;7(8):e43553. doi: 10.1371/journal.pone.0043553. Epub 2012 Aug 20.

12.

Ihh and Runx2/Runx3 signaling interact to coordinate early chondrogenesis: a mouse model.

Kim EJ, Cho SW, Shin JO, Lee MJ, Kim KS, Jung HS.

PLoS One. 2013;8(2):e55296. doi: 10.1371/journal.pone.0055296. Epub 2013 Feb 1.

13.

The short stature homeobox 2 (Shox2)-bone morphogenetic protein (BMP) pathway regulates dorsal mesenchymal protrusion development and its temporary function as a pacemaker during cardiogenesis.

Sun C, Yu D, Ye W, Liu C, Gu S, Sinsheimer NR, Song Z, Li X, Chen C, Song Y, Wang S, Schrader L, Chen Y.

J Biol Chem. 2015 Jan 23;290(4):2007-23. doi: 10.1074/jbc.M114.619007. Epub 2014 Dec 8.

14.

Studies on the role of Dlx5 in regulation of chondrocyte differentiation during endochondral ossification in the developing mouse limb.

Chin HJ, Fisher MC, Li Y, Ferrari D, Wang CK, Lichtler AC, Dealy CN, Kosher RA.

Dev Growth Differ. 2007 Aug;49(6):515-21. Epub 2007 Jun 7.

PMID:
17555518
15.

Shox2 function couples neural, muscular and skeletal development in the proximal forelimb.

Vickerman L, Neufeld S, Cobb J.

Dev Biol. 2011 Feb 15;350(2):323-36. doi: 10.1016/j.ydbio.2010.11.031. Epub 2010 Dec 13.

16.

Functional role of Runx3 in the regulation of aggrecan expression during cartilage development.

Wigner NA, Soung do Y, Einhorn TA, Drissi H, Gerstenfeld LC.

J Cell Physiol. 2013 Nov;228(11):2232-42. doi: 10.1002/jcp.24396.

17.

Shox2-deficient mice exhibit a rare type of incomplete clefting of the secondary palate.

Yu L, Gu S, Alappat S, Song Y, Yan M, Zhang X, Zhang G, Jiang Y, Zhang Z, Zhang Y, Chen Y.

Development. 2005 Oct;132(19):4397-406. Epub 2005 Sep 1.

18.

Targeting Runx2 expression in hypertrophic chondrocytes impairs endochondral ossification during early skeletal development.

Ding M, Lu Y, Abbassi S, Li F, Li X, Song Y, Geoffroy V, Im HJ, Zheng Q.

J Cell Physiol. 2012 Oct;227(10):3446-56. doi: 10.1002/jcp.24045.

19.

Runx1/AML1/Cbfa2 mediates onset of mesenchymal cell differentiation toward chondrogenesis.

Wang Y, Belflower RM, Dong YF, Schwarz EM, O'Keefe RJ, Drissi H.

J Bone Miner Res. 2005 Sep;20(9):1624-36. Epub 2005 May 23.

20.

Cbfb regulates bone development by stabilizing Runx family proteins.

Qin X, Jiang Q, Matsuo Y, Kawane T, Komori H, Moriishi T, Taniuchi I, Ito K, Kawai Y, Rokutanda S, Izumi S, Komori T.

J Bone Miner Res. 2015 Apr;30(4):706-14. doi: 10.1002/jbmr.2379.

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