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Items: 1 to 20 of 73

1.

Lats2 is an essential mitotic regulator required for the coordination of cell division.

Yabuta N, Okada N, Ito A, Hosomi T, Nishihara S, Sasayama Y, Fujimori A, Okuzaki D, Zhao H, Ikawa M, Okabe M, Nojima H.

J Biol Chem. 2007 Jun 29;282(26):19259-71. Epub 2007 May 3.

2.

Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity.

McPherson JP, Tamblyn L, Elia A, Migon E, Shehabeldin A, Matysiak-Zablocki E, Lemmers B, Salmena L, Hakem A, Fish J, Kassam F, Squire J, Bruneau BG, Hande MP, Hakem R.

EMBO J. 2004 Sep 15;23(18):3677-88. Epub 2004 Sep 2.

3.

LATS2-Ajuba complex regulates gamma-tubulin recruitment to centrosomes and spindle organization during mitosis.

Abe Y, Ohsugi M, Haraguchi K, Fujimoto J, Yamamoto T.

FEBS Lett. 2006 Feb 6;580(3):782-8. Epub 2006 Jan 9.

4.

The tumor suppressor Lats2 is pivotal in Aurora A and Aurora B signaling during mitosis.

Yabuta N, Mukai S, Okada N, Aylon Y, Nojima H.

Cell Cycle. 2011 Aug 15;10(16):2724-36. Epub 2011 Aug 15.

PMID:
21822051
5.

The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase.

Toji S, Yabuta N, Hosomi T, Nishihara S, Kobayashi T, Suzuki S, Tamai K, Nojima H.

Genes Cells. 2004 May;9(5):383-97.

6.

Spatial regulation of cytokinesis by the Kin1 and Pom1 kinases in fission yeast.

La Carbona S, Le Goff X.

Curr Genet. 2006 Dec;50(6):377-91. Epub 2006 Sep 20.

PMID:
16988828
7.

Lats2, a putative tumor suppressor, inhibits G1/S transition.

Li Y, Pei J, Xia H, Ke H, Wang H, Tao W.

Oncogene. 2003 Jul 10;22(28):4398-405.

PMID:
12853976
8.

Citron kinase is a regulator of mitosis and neurogenic cytokinesis in the neocortical ventricular zone.

LoTurco JJ, Sarkisian MR, Cosker L, Bai J.

Cereb Cortex. 2003 Jun;13(6):588-91.

PMID:
12764032
9.

KIBRA regulates aurora kinase activity and is required for precise chromosome alignment during mitosis.

Zhang L, Iyer J, Chowdhury A, Ji M, Xiao L, Yang S, Chen Y, Tsai MY, Dong J.

J Biol Chem. 2012 Oct 5;287(41):34069-77. doi: 10.1074/jbc.M112.385518. Epub 2012 Aug 17.

10.

Lats1 suppresses centrosome overduplication by modulating the stability of Cdc25B.

Mukai S, Yabuta N, Yoshida K, Okamoto A, Miura D, Furuta Y, Abe T, Nojima H.

Sci Rep. 2015 Nov 4;5:16173. doi: 10.1038/srep16173.

11.

A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization.

Aylon Y, Michael D, Shmueli A, Yabuta N, Nojima H, Oren M.

Genes Dev. 2006 Oct 1;20(19):2687-700.

12.

The budding yeast Dbf2 protein kinase localises to the centrosome and moves to the bud neck in late mitosis.

Frenz LM, Lee SE, Fesquet D, Johnston LH.

J Cell Sci. 2000 Oct;113 Pt 19:3399-408.

13.

Fission yeast Clp1p phosphatase regulates G2/M transition and coordination of cytokinesis with cell cycle progression.

Trautmann S, Wolfe BA, Jorgensen P, Tyers M, Gould KL, McCollum D.

Curr Biol. 2001 Jun 26;11(12):931-40.

14.

Putative tumor suppressor Lats2 induces apoptosis through downregulation of Bcl-2 and Bcl-x(L).

Ke H, Pei J, Ni Z, Xia H, Qi H, Woods T, Kelekar A, Tao W.

Exp Cell Res. 2004 Aug 15;298(2):329-38.

PMID:
15265683
15.

ATM is activated by mitotic stress and suppresses centrosome amplification in primary but not in tumor cells.

Shen K, Wang Y, Brooks SC, Raz A, Wang YA.

J Cell Biochem. 2006 Dec 1;99(5):1267-74.

PMID:
16775842
16.

Choice of Plk1 docking partners during mitosis and cytokinesis is controlled by the activation state of Cdk1.

Neef R, Gruneberg U, Kopajtich R, Li X, Nigg EA, Sillje H, Barr FA.

Nat Cell Biol. 2007 Apr;9(4):436-44. Epub 2007 Mar 11.

PMID:
17351640
17.

Human LATS1 is a mitotic exit network kinase.

Bothos J, Tuttle RL, Ottey M, Luca FC, Halazonetis TD.

Cancer Res. 2005 Aug 1;65(15):6568-75.

18.
19.

Aurora B -TACC1 protein complex in cytokinesis.

Delaval B, Ferrand A, Conte N, Larroque C, Hernandez-Verdun D, Prigent C, Birnbaum D.

Oncogene. 2004 Jun 3;23(26):4516-22.

PMID:
15064709
20.

MicroRNA-373 (miR-373) post-transcriptionally regulates large tumor suppressor, homolog 2 (LATS2) and stimulates proliferation in human esophageal cancer.

Lee KH, Goan YG, Hsiao M, Lee CH, Jian SH, Lin JT, Chen YL, Lu PJ.

Exp Cell Res. 2009 Sep 10;315(15):2529-38. doi: 10.1016/j.yexcr.2009.06.001. Epub 2009 Jun 6.

PMID:
19501585

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