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Chromosome 12q harbors multiple genetic loci related to asthma and asthma-related phenotypes.

Raby BA, Silverman EK, Lazarus R, Lange C, Kwiatkowski DJ, Weiss ST.

Hum Mol Genet. 2003 Aug 15;12(16):1973-9.


The genetics of autism.

Muhle R, Trentacoste SV, Rapin I.

Pediatrics. 2004 May;113(5):e472-86. Review.


A genome-wide search for linkage to asthma phenotypes in the genetics of asthma international network families: evidence for a major susceptibility locus on chromosome 2p.

Pillai SG, Chiano MN, White NJ, Speer M, Barnes KC, Carlsen K, Gerritsen J, Helms P, Lenney W, Silverman M, Sly P, Sundy J, Tsanakas J, von Berg A, Whyte M, Varsani S, Skelding P, Hauser M, Vance J, Pericak-Vance M, Burns DK, Middleton LT, Brewster SR, Anderson WH, Riley JH.

Eur J Hum Genet. 2006 Mar;14(3):307-16. Erratum in: Eur J Hum Genet. 2007 Jun;15(6):714.


Genome-wide linkage analysis of lipids in nondiabetic Chinese and Japanese from the SAPPHIRe family study.

Hsiao CF, Chiu YF, Chiang FT, Ho LT, Lee WJ, Hung YJ, Chen YD, Donlon TA, Jorgenson E, Curb D, Risch N, Hsiung CA; SAPPHIRe Study Group.

Am J Hypertens. 2006 Dec;19(12):1270-7.


Genetic regulation of Dermatophagoides pteronyssinus-specific IgE responsiveness: a genome-wide multipoint linkage analysis in families recruited through 2 asthmatic sibs. Collaborative Study on the Genetics of Asthma (CSGA).

Hizawa N, Freidhoff LR, Chiu YF, Ehrlich E, Luehr CA, Anderson JL, Duffy DL, Dunston GM, Weber JL, Huang SK, Barnes KC, Marsh DG, Beaty TH.

J Allergy Clin Immunol. 1998 Sep;102(3):436-42.


Major quantitative trait locus for eosinophil count is located on chromosome 2q.

Evans DM, Zhu G, Duffy DL, Montgomery GW, Frazer IH, Martin NG.

J Allergy Clin Immunol. 2004 Oct;114(4):826-30.


Genetic mapping of a 17q chromosomal region linked to obesity phenotypes in the IRAS family study.

Sutton BS, Langefeld CD, Campbell JK, Haffner SM, Norris JM, Scherzinger AL, Wagenknecht LE, Bowden DW.

Int J Obes (Lond). 2006 Sep;30(9):1433-41. Epub 2006 Mar 7.


Familial thoracic aortic aneurysms and dissections: genetic heterogeneity with a major locus mapping to 5q13-14.

Guo D, Hasham S, Kuang SQ, Vaughan CJ, Boerwinkle E, Chen H, Abuelo D, Dietz HC, Basson CT, Shete SS, Milewicz DM.

Circulation. 2001 May 22;103(20):2461-8.


Evidence for a major quantitative trait locus on chromosome 17q21 affecting low-density lipoprotein peak particle diameter.

Bossé Y, Pérusse L, Després JP, Lamarche B, Chagnon YC, Rice T, Rao DC, Bouchard C, Vohl MC.

Circulation. 2003 May 13;107(18):2361-8. Epub 2003 May 5.


A genome-wide linkage scan for dietary energy and nutrient intakes: the Health, Risk Factors, Exercise Training, and Genetics (HERITAGE) Family Study.

Collaku A, Rankinen T, Rice T, Leon AS, Rao DC, Skinner JS, Wilmore JH, Bouchard C.

Am J Clin Nutr. 2004 May;79(5):881-6.


Evidence for a gene influencing heart rate on chromosome 5p13-14 in a meta-analysis of genome-wide scans from the NHLBI Family Blood Pressure Program.

Laramie JM, Wilk JB, Hunt SC, Ellison RC, Chakravarti A, Boerwinkle E, Myers RH.

BMC Med Genet. 2006 Mar 1;7:17.


Genome-wide linkage meta-analysis identifies susceptibility loci at 2q34 and 13q31.3 for genetic generalized epilepsies.

EPICURE Consortium, Leu C, de Kovel CG, Zara F, Striano P, Pezzella M, Robbiano A, Bianchi A, Bisulli F, Coppola A, Giallonardo AT, Beccaria F, Trenité DK, Lindhout D, Gaus V, Schmitz B, Janz D, Weber YG, Becker F, Lerche H, Kleefuss-Lie AA, Hallman K, Kunz WS, Elger CE, Muhle H, Stephani U, Møller RS, Hjalgrim H, Mullen S, Scheffer IE, Berkovic SF, Everett KV, Gardiner MR, Marini C, Guerrini R, Lehesjoki AE, Siren A, Nabbout R, Baulac S, Leguern E, Serratosa JM, Rosenow F, Feucht M, Unterberger I, Covanis A, Suls A, Weckhuysen S, Kaneva R, Caglayan H, Turkdogan D, Baykan B, Bebek N, Ozbek U, Hempelmann A, Schulz H, Rüschendorf F, Trucks H, Nürnberg P, Avanzini G, Koeleman BP, Sander T.

Epilepsia. 2012 Feb;53(2):308-18. doi: 10.1111/j.1528-1167.2011.03379.x. Epub 2012 Jan 13.


Genome-wide linkage analyses of total serum IgE using variance components analysis in asthmatic families.

Mathias RA, Freidhoff LR, Blumenthal MN, Meyers DA, Lester L, King R, Xu JF, Solway J, Barnes KC, Pierce J, Stine OC, Togias A, Oetting W, Marshik PL, Hetmanski JB, Huang SK, Ehrlich E, Dunston GM, Malveaux F, Banks-Schlegel S, Cox NJ, Bleecker E, Ober C, Beaty TH, Rich SS; CSGA (Collaborative Study of the Genetics of Asthma).

Genet Epidemiol. 2001 Apr;20(3):340-55.


Two-trait-locus linkage analyses of asthma susceptibility.

Nath SK, Chen CH, Schork NJ.

Genet Epidemiol. 2001;21 Suppl 1:S278-83.


Approaches to genetic linkage analysis.

Teare MD.

Methods Mol Biol. 2011;713:55-67. doi: 10.1007/978-1-60327-416-6_5.


Sex- and age-of-onset-based locus heterogeneity in asthma.

Srivastava A, Cotton C, Paterson AD.

Genet Epidemiol. 2001;21 Suppl 1:S154-9.


A genomewide search for quantitative-trait loci underlying asthma.

Xu X, Fang Z, Wang B, Chen C, Guang W, Jin Y, Yang J, Lewitzky S, Aelony A, Parker A, Meyer J, Weiss ST, Xu X.

Am J Hum Genet. 2001 Dec;69(6):1271-7. Epub 2001 Oct 22. Erratum in: Am J Hum Genet 2002 Jul;71(1):215.

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